Comparative Effects of High-Intensity Interval Training and Continuous Endurance Training Among Prediabetic Patients
2026年7月17日 更新者：Riphah International University
Comparative Effects of High-Intensity Interval Training and Continuous Endurance Training on Glycemic Control, BMI, Vo₂ Max, Pulmonary Function, and Physical Activity Among Prediabetic Patients
Prediabetics is a condition where blood sugar levels are normal but not yet high enough to be diagnosed as type 2 diabetes.
This phase offers a crucial point for timely intervention to delay or prevent type 2 diabetes.
The objective of the study will be to find the effects of high intensity interval and continuous endurance training on glycemic control, BMI, Vo2 Max, pulmonary function and physical activity among prediabetic patients.
Study design will be randomized control trial.
Total 80 participants will be enrolled in study.
The data will be collected from faculty of Riphah International University, Lahore.
The study will be completed within 8 months after approval of synopsis.
A simple random sampling will be used to assign the groups; group A and group B. Group A will be assigned high intensity interval training and group B will be assigned to continuous training.
調査の概要
状態
募集
詳細な説明
Prediabetics is a condition where blood sugar levels are normal but not yet high enough to be diagnosed as type 2 diabetes.
This phase offers a crucial point for timely intervention to delay or prevent type 2 diabetes.
The objective of the study will be to find the effects of high intensity interval and continuous endurance training on glycemic control, BMI, Vo2 Max, pulmonary function and physical activity among prediabetic patients.
Study design will be randomized control trial.
Total 80 participants will be enrolled in study.
The data will be collected from faculty of Riphah International University, Lahore.
The study will be completed within 8 months after approval of synopsis.
A simple random sampling will be used to assign the groups: group A and group B. Group A will be assigned high intensity interval training, and group B will be assigned to continuous training.
Both interventions will be conducted over a 12-week period, with pre- and post-intervention assessments.
Each exercise session constitutes a 5-minute warm up and finished with a 5-minute cool-down.
Participants aged between 35 to 54 years with sedentary lifestyle, Stable medical condition, and stable body weight with changes less 3kg in the past 6 months will be included in this study.
The study will exclude individuals with uncontrolled hypertension, history of heart disease, myocardial infarction and stroke and diagnosed type 2 diabetes, use of specific medications, severe obesity, high fasting blood glucose, previous history of respiratory problems, and smoking.
Primary outcomes include changes in fasting blood glucose, HbA1c levels, and insulin sensitivity.
Pre and post values of glucose level and FEV1, FVC and FEV1/FVC will be calculated.
Secondary outcomes will assess BMI, VO₂ max through graded exercise testing, pulmonary function using spirometry, and physical activity levels measured by validated questionnaire of short form of IPAQ-SF.
Data will be analysed using SPSS 24 and Shapiro wilks test will be applied to assess the normality of data.
After assesing the normality of data paired sample/independent t test/ANOVA test will be applied to find which technique will be more beneficial for prediabetic patients.
研究の種類
介入
入学 (推定)
80
段階
- 適用できない
連絡先と場所
このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。
研究連絡先
- 名前：Muhammad Iqbal Tariq, pHD
- 電話番号：333826752
- メール：iqbal.tariq@riphah.edu.pk
研究連絡先のバックアップ
- 名前：Misdaq Batool, MS PT
- 電話番号：03466584498
- メール：misdaaqbatool@yahoo.com.ph
研究場所
-
-
Punjab Province
-
Lahore、Punjab Province、パキスタン、40100
- 募集
- Rihpah international university Lahore campus
-
コンタクト：
- Misdaq Batool, MS PT
- 電話番号：03466584498
- メール：misdaaqbatool@yahoo.com.ph
-
コンタクト：
- Areeza Mansha, MS PT
- 電話番号：03363405060
- メール：Areeza154@gmail.com
-
-
参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
- 大人
健康ボランティアの受け入れ
はい
説明
Inclusion Criteria:
Sedentary lifestyle (Individuals reporting minimal structured physical activity e.g., <30 minutes of exercise per week) .
- Stable Medical Condition (No history of significant cardiovascular events, uncontrolled hypertension, or other major comorbidities).
- Stable Body Weight (Stable body weight with changes less than 3 kg in the past 6 months).
Exclusion Criteria:
uncontrolled hypertension
- history of heart disease
- myocardial infarction
- stroke
- Use of Specific Medications (Current use of insulin or other medications affecting glucose metabolism or exercise response)
- Severe Obesity (Individuals with a BMI ≥ 40 kg/m)
- High fasting blood glucose (Fasting blood glucose of >100mg.dl-1)
- Previous history of respiratory problems
- Smoking
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：処理
- 割り当て：ランダム化
- 介入モデル：並列代入
- マスキング：ダブル
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
|
アクティブコンパレータ：High-Intensity Interval Training
High intensity interval training is a training method that involves repeated bouts of short duration, highintensity exercise typicallyb performed at ≥ 85 -95% of maximal heart rate or vo2 max interspersed with period of low intensity recovery or complete rest.
|
5 minutes warm up including walk
|
|
アクティブコンパレータ：Continuous Endurance Training
Continuous endurance training also called moderate intensity continuous training involves sustained exercise at a moderate and steady intensity typically 60to 75% of vo2 max or maximal heart rate performed for a continuous duration without rest intervals
|
5 to 10 minute walking (warm up )
|
この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
fasting blood glucose
時間枠：12 weeks
|
Participants were instructed to fast overnight for 8 to 12 hours.
FBG was measured using an automated glucose analyzer
|
12 weeks
|
|
Forced Vital Capacity
時間枠：12 weeks
|
Spirometry using devices like a digital spirometry will be used.
Forced Vital Capacity (FVC) will be measured in liters (L) using spirometry.
FVC represents the maximum volume of air that can be forcefully exhaled after a maximal inspiration.
|
12 weeks
|
|
Forced Expiratory Volume in One Second
時間枠：12 weeks
|
Forced Expiratory Volume in One Second (FEV₁) will be measured in liters (L) using spirometry.
FEV₁ represents the volume of air exhaled during the first second of a forced expiratory maneuver.
|
12 weeks
|
|
FEV₁/FVC ratio
時間枠：12 weeks
|
The FEV₁/FVC ratio will be expressed as a percentage (%) and calculated from spirometric measurements to assess the degree of airflow limitation.
|
12 weeks
|
|
HbA1c
時間枠：12 weeks
|
HbA1c was assesed through high performance liquid chromatography
|
12 weeks
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Body mass index (BMI)
時間枠：12 weeks
|
Participants weight was measured using a calibrated digital scale with minimal clothing and no shoes height was measured using a wall mounted stadiometer with participants standing upright
|
12 weeks
|
|
IPAQ (short form) questionnaire
時間枠：12 weeks
|
International physical activity questionnaire is applicable for survey among 18 to 65 years to Assess the level of physical activity along different countries. It is developed in 2 Versions; first is long version (27 items), and the second is the short version (7 items). We will use IPAQ short version which consists of job, transport, domestic, and leisure time physical activity domains. Moderate and high-intensity walking and sitting time activities are addressed in this questionnaire |
12 weeks
|
|
Maximal Oxygen Uptake (VO₂max)
時間枠：12 weeks
|
In this research VO2 Max will be measured through a submaximal 6 mint walk test
|
12 weeks
|
協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
捜査官
- 主任研究者：Arjumand Bano, MS、Riphah International University
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (実際)
2026年5月1日
一次修了 (推定)
2026年8月1日
研究の完了 (推定)
2026年8月1日
試験登録日
最初に提出
2026年6月8日
QC基準を満たした最初の提出物
2026年7月17日
最初の投稿 (実際)
2026年7月20日
学習記録の更新
投稿された最後の更新 (実際)
2026年7月20日
QC基準を満たした最後の更新が送信されました
2026年7月17日
最終確認日
2026年7月1日
詳しくは
本研究に関する用語
キーワード
追加の関連 MeSH 用語
その他の研究ID番号
- REC/RCR & AHS/25/0302
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
いいえ
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
いいえ
米国FDA規制機器製品の研究
いいえ
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