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Comparative Effects of High-Intensity Interval Training and Continuous Endurance Training Among Prediabetic Patients

2026年7月17日 更新者:Riphah International University

Comparative Effects of High-Intensity Interval Training and Continuous Endurance Training on Glycemic Control, BMI, Vo₂ Max, Pulmonary Function, and Physical Activity Among Prediabetic Patients

Prediabetics is a condition where blood sugar levels are normal but not yet high enough to be diagnosed as type 2 diabetes. This phase offers a crucial point for timely intervention to delay or prevent type 2 diabetes. The objective of the study will be to find the effects of high intensity interval and continuous endurance training on glycemic control, BMI, Vo2 Max, pulmonary function and physical activity among prediabetic patients. Study design will be randomized control trial. Total 80 participants will be enrolled in study. The data will be collected from faculty of Riphah International University, Lahore. The study will be completed within 8 months after approval of synopsis. A simple random sampling will be used to assign the groups; group A and group B. Group A will be assigned high intensity interval training and group B will be assigned to continuous training.

研究概览

详细说明

Prediabetics is a condition where blood sugar levels are normal but not yet high enough to be diagnosed as type 2 diabetes. This phase offers a crucial point for timely intervention to delay or prevent type 2 diabetes. The objective of the study will be to find the effects of high intensity interval and continuous endurance training on glycemic control, BMI, Vo2 Max, pulmonary function and physical activity among prediabetic patients. Study design will be randomized control trial. Total 80 participants will be enrolled in study. The data will be collected from faculty of Riphah International University, Lahore. The study will be completed within 8 months after approval of synopsis. A simple random sampling will be used to assign the groups: group A and group B. Group A will be assigned high intensity interval training, and group B will be assigned to continuous training. Both interventions will be conducted over a 12-week period, with pre- and post-intervention assessments. Each exercise session constitutes a 5-minute warm up and finished with a 5-minute cool-down. Participants aged between 35 to 54 years with sedentary lifestyle, Stable medical condition, and stable body weight with changes less 3kg in the past 6 months will be included in this study. The study will exclude individuals with uncontrolled hypertension, history of heart disease, myocardial infarction and stroke and diagnosed type 2 diabetes, use of specific medications, severe obesity, high fasting blood glucose, previous history of respiratory problems, and smoking. Primary outcomes include changes in fasting blood glucose, HbA1c levels, and insulin sensitivity. Pre and post values of glucose level and FEV1, FVC and FEV1/FVC will be calculated. Secondary outcomes will assess BMI, VO₂ max through graded exercise testing, pulmonary function using spirometry, and physical activity levels measured by validated questionnaire of short form of IPAQ-SF. Data will be analysed using SPSS 24 and Shapiro wilks test will be applied to assess the normality of data. After assesing the normality of data paired sample/independent t test/ANOVA test will be applied to find which technique will be more beneficial for prediabetic patients.

研究类型

介入性

注册 (估计的)

80

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习联系方式

研究联系人备份

学习地点

    • Punjab Province
      • Lahore、Punjab Province、巴基斯坦、40100
        • 招聘中
        • Rihpah international university Lahore campus
        • 接触:
        • 接触:

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

  • 成人

接受健康志愿者

是的

描述

Inclusion Criteria:

  • Sedentary lifestyle (Individuals reporting minimal structured physical activity e.g., <30 minutes of exercise per week) .

    • Stable Medical Condition (No history of significant cardiovascular events, uncontrolled hypertension, or other major comorbidities).
    • Stable Body Weight (Stable body weight with changes less than 3 kg in the past 6 months).

Exclusion Criteria:

  • uncontrolled hypertension

    • history of heart disease
    • myocardial infarction
    • stroke
    • Use of Specific Medications (Current use of insulin or other medications affecting glucose metabolism or exercise response)
    • Severe Obesity (Individuals with a BMI ≥ 40 kg/m)
    • High fasting blood glucose (Fasting blood glucose of >100mg.dl-1)
    • Previous history of respiratory problems
    • Smoking

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:治疗
  • 分配:随机化
  • 介入模型:并行分配
  • 屏蔽:双倍的

武器和干预

参与者组/臂
干预/治疗
有源比较器:High-Intensity Interval Training
High intensity interval training is a training method that involves repeated bouts of short duration, highintensity exercise typicallyb performed at ≥ 85 -95% of maximal heart rate or vo2 max interspersed with period of low intensity recovery or complete rest.

5 minutes warm up including walk

  • 30s fast stairs climbing
  • 60s slow walk down
  • Repeat 5 to 6 rounds
  • 5 minute stretching or slow walk (cool down)
有源比较器:Continuous Endurance Training
Continuous endurance training also called moderate intensity continuous training involves sustained exercise at a moderate and steady intensity typically 60to 75% of vo2 max or maximal heart rate performed for a continuous duration without rest intervals

5 to 10 minute walking (warm up )

  • 25 to 30minutes at 60 to 70 %continuous training
  • Continuous walk for 15 to 20 minutes.
  • 5 to 10 minutes stretching (cool down)

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
fasting blood glucose
大体时间:12 weeks
Participants were instructed to fast overnight for 8 to 12 hours. FBG was measured using an automated glucose analyzer
12 weeks
Forced Vital Capacity
大体时间:12 weeks
Spirometry using devices like a digital spirometry will be used. Forced Vital Capacity (FVC) will be measured in liters (L) using spirometry. FVC represents the maximum volume of air that can be forcefully exhaled after a maximal inspiration.
12 weeks
Forced Expiratory Volume in One Second
大体时间:12 weeks
Forced Expiratory Volume in One Second (FEV₁) will be measured in liters (L) using spirometry. FEV₁ represents the volume of air exhaled during the first second of a forced expiratory maneuver.
12 weeks
FEV₁/FVC ratio
大体时间:12 weeks
The FEV₁/FVC ratio will be expressed as a percentage (%) and calculated from spirometric measurements to assess the degree of airflow limitation.
12 weeks
HbA1c
大体时间:12 weeks
HbA1c was assesed through high performance liquid chromatography
12 weeks

次要结果测量

结果测量
措施说明
大体时间
Body mass index (BMI)
大体时间:12 weeks
Participants weight was measured using a calibrated digital scale with minimal clothing and no shoes height was measured using a wall mounted stadiometer with participants standing upright
12 weeks
IPAQ (short form) questionnaire
大体时间:12 weeks

International physical activity questionnaire is applicable for survey among 18 to 65 years to Assess the level of physical activity along different countries. It is developed in 2 Versions; first is long version (27 items), and the second is the short version (7 items). We will use IPAQ short version which consists of job, transport, domestic, and leisure time physical activity domains.

Moderate and high-intensity walking and sitting time activities are addressed in this questionnaire

12 weeks
Maximal Oxygen Uptake (VO₂max)
大体时间:12 weeks
In this research VO2 Max will be measured through a submaximal 6 mint walk test
12 weeks

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 首席研究员:Arjumand Bano, MS、Riphah International University

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2026年5月1日

初级完成 (估计的)

2026年8月1日

研究完成 (估计的)

2026年8月1日

研究注册日期

首次提交

2026年6月8日

首先提交符合 QC 标准的

2026年7月17日

首次发布 (实际的)

2026年7月20日

研究记录更新

最后更新发布 (实际的)

2026年7月20日

上次提交的符合 QC 标准的更新

2026年7月17日

最后验证

2026年7月1日

更多信息

与本研究相关的术语

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)?

不

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

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