Effect of Menstrual Cycle Phase on Pain Perception and Anxiety During Non-Surgical Periodontal Treatment (MAPP)
2026年7月20日 更新者：Seda Nur Kabasakal、Karadeniz Technical University
Comparison of Pain Perception and Anxiety Levels During Non-Surgical Periodontal Treatment in Female Patients With Stage II and III Periodontitis at Different Phases of the Menstrual Cycle
This study evaluates the effect of menstrual cycle phases on pain perception and dental anxiety during non-surgical periodontal therapy in premenopausal women with Stage II and III periodontitis.
Pain and anxiety levels were assessed using VAS and DAS scales in perimenstrual and postmenstrual phases.
Periodontal treatment outcomes were also recorded before and after therapy.
調査の概要
詳細な説明
This study investigated the influence of menstrual cycle phases on pain perception and anxiety levels during non-surgical periodontal therapy (NSPT) in systemically healthy premenopausal women diagnosed with Stage II and III periodontitis.
A total of 36 participants were included.
Clinical periodontal parameters, including probing pocket depth (PPD), clinical attachment level (CAL), gingival index (GI), plaque index (PI), and bleeding on probing (BoP), were recorded before and after NSPT.
Pain perception was assessed using the Visual Analog Scale (VAS), and dental anxiety was evaluated using the Corah Dental Anxiety Scale (DAS).
NSPT was performed without local anesthesia using a split-mouth design.
Outcomes were compared between perimenstrual and postmenstrual phases.
研究の種類
観察的
入学 (実際)
36
連絡先と場所
このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。
研究場所
-
-
Trabzon
-
Trabzon、Trabzon、トルコ（Türkiye）、61080
- Karadeniz Technical University Faculty of Dentistry, Department of Periodontology
-
-
参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
- 子
- 大人
- 高齢者
健康ボランティアの受け入れ
いいえ
サンプリング方法
非確率サンプル
調査対象母集団
Systemically healthy premenopausal female patients diagnosed with Stage II and III periodontitis attending the Department of Periodontology were included in the study.
説明
Inclusion Criteria:
- Female patients aged 18 years and older diagnosed with Stage II and III periodontitis, systemically healthy, and not using medications affecting pain perception or hormonal status. Participants with regular menstrual cycles were included.
Exclusion Criteria:
- Patients with systemic diseases, pregnancy or lactation, use of analgesic, anti-inflammatory or hormonal medications, smokers (if excluded), and those with irregular menstrual cycles were excluded.
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか？
デザインの詳細
コホートと介入
グループ/コホート |
介入・治療 |
|---|---|
|
Perimenstrual Phase Group
Female patients with Stage II and III periodontitis who underwent non-surgical periodontal therapy during the perimenstrual phase.
|
Standard non-surgical periodontal therapy including scaling and root planing performed without local anesthesia.
|
|
Postmenstrual Phase Group
Female patients with Stage II and III periodontitis who underwent non-surgical periodontal therapy during the postmenstrual phase.
|
Standard non-surgical periodontal therapy including scaling and root planing performed without local anesthesia.
|
この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Pain perception
時間枠：Immediately after completion of each treatment session (session duration was not fixed and varied according to the extent of treatment required)
|
Pain perception during non-surgical periodontal therapy assessed using the Visual Analog Scale (VAS; score range: 0-10), where higher scores indicate greater pain intensity, across menstrual cycle phases.
|
Immediately after completion of each treatment session (session duration was not fixed and varied according to the extent of treatment required)
|
|
Dental Anxiety
時間枠：Immediately after completion of each treatment session (session duration was not fixed and varied according to the extent of treatment required)
|
Dental anxiety during non-surgical periodontal therapy was assessed using the Corah Dental Anxiety Scale (DAS; score range: 4-20).
The scale consists of four questions related to different dental treatment situations, each with five response options of increasing intensity.
Participants were asked to select the response that best reflected their level of anxiety.
Higher scores indicate greater anxiety levels, across menstrual cycle phases.
|
Immediately after completion of each treatment session (session duration was not fixed and varied according to the extent of treatment required)
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Probing Pocket Depth (PPD)
時間枠：Baseline (pre-treatment) and 6 weeks after completion of non-surgical periodontal therapy
|
PPD was measured in millimeters at six sites per tooth using a periodontal probe, and mean values were calculated per participant.
|
Baseline (pre-treatment) and 6 weeks after completion of non-surgical periodontal therapy
|
|
Clinical Attachment Level (CAL)
時間枠：Baseline (pre-treatment) and 6 weeks after completion of non-surgical periodontal therapy
|
CAL was measured in millimeters at six sites per tooth using a periodontal probe, and mean values were calculated per participant.
|
Baseline (pre-treatment) and 6 weeks after completion of non-surgical periodontal therapy
|
|
Gingival Index (GI)
時間枠：Baseline (pre-treatment) and 6 weeks after completion of non-surgical periodontal therapy
|
GI was assessed at four sites per tooth to evaluate gingival inflammation, and mean scores were calculated per participant.
|
Baseline (pre-treatment) and 6 weeks after completion of non-surgical periodontal therapy
|
|
Plaque Index (PI)
時間枠：Baseline (pre-treatment) and 6 weeks after completion of non-surgical periodontal therapy
|
PI was assessed at four sites per tooth to evaluate plaque accumulation, and mean scores were calculated per participant.
|
Baseline (pre-treatment) and 6 weeks after completion of non-surgical periodontal therapy
|
|
Bleeding on Probing (BoP)
時間枠：Baseline (pre-treatment) and 6 weeks after completion of non-surgical periodontal therapy
|
BoP was recorded as the percentage of sites showing bleeding within 10 seconds after probing.
|
Baseline (pre-treatment) and 6 weeks after completion of non-surgical periodontal therapy
|
協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (実際)
2024年6月1日
一次修了 (実際)
2025年5月1日
研究の完了 (実際)
2025年5月1日
試験登録日
最初に提出
2026年7月2日
QC基準を満たした最初の提出物
2026年7月20日
最初の投稿 (実際)
2026年7月22日
学習記録の更新
投稿された最後の更新 (実際)
2026年7月22日
QC基準を満たした最後の更新が送信されました
2026年7月20日
最終確認日
2026年7月1日
詳しくは
本研究に関する用語
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
いいえ
IPD プランの説明
Individual participant data will not be shared due to patient confidentiality and privacy considerations.
Data may contain sensitive clinical and personal health information.
Therefore, access to the dataset will be restricted to the study investigators only.
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米国FDA規制医薬品の研究
いいえ
米国FDA規制機器製品の研究
いいえ
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