Brain Perfusion and Hemodynamic Stability in Patients Undergoing Radiofrequency Ablation of Ventricular Tachycardia
Assessment of Intracardiac and Surgace Electrogram Characteristics Correlated to Brain Perfusion and Hemodynamic Stability in Patients Undergoing Radiofrequency Ablation of Ventricular Tachycardia
Ventricular tachycardia (VT) is a life-threatening, fast heart rhythm that starts in the lower chambers of the heart (the ventricles). This fast heartbeat is caused by abnormal electrical pathways located in the heart tissue. A standard procedure called a catheter ablation has been used for several years to help correct these abnormal pathways and, in some cases, improve or even eliminate the ventricular tachycardia.
During a VT ablation it is routine to monitor your vital signs (blood pressure, heart rate, and oxygen saturation in your blood). If you choose to participate in this study we will also monitor your cerebral oximetry, the amount of blood flow and oxygen saturation to your brain during the ablation.
By doing this study, we hope to have a better understanding of patients' blood and oxygen flow to their brain during an episode of Ventricular Tachycardia (VT).
연구 개요
연구 유형
등록 (실제)
연락처 및 위치
연구 장소
-
-
Kansas
-
Kansas City, Kansas, 미국, 66160
- University of Kansas Medical Center
-
-
참여기준
자격 기준
공부할 수 있는 나이
건강한 자원 봉사자를 받아들입니다
연구 대상 성별
샘플링 방법
연구 인구
설명
Inclusion Criteria:
- Able to give informed consent
- Have implantable defibrillator in-situ and are undergoing ablation procedure for ventricular tachycardia
Exclusion Criteria:
- Patients who have been hypotensive with systolic blood pressure of < 80mm Hg prior to procedure
- Cerebral event as defined by Cerebrovascular Accident or Transient Ischemia Attack within six months prior to procedure
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
코호트 및 개입
그룹/코호트 |
개입 / 치료 |
|---|---|
|
Ventricular Tachycardia
Participants in cohort will have implantable defibrillators in-situ and are undergoing ablation procedure for ventricular tachycardia.
|
Participants will be asked questions relating to pre-procedure items and be asked to complete an MMSE.
Subjects receive standard of care surgery.
Data collected from procedures before, during and after surgery.
|
연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
Identify clinical, EKG and EGM characteristics of hemodynamically unstable VT
기간: Change from Baseline to 24-48 hours after surgery
|
The investigator will be evaluating the relationship of the oxygenation level of the brain during a Ventricular Tachycardia ablation.
|
Change from Baseline to 24-48 hours after surgery
|
2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
MMSE to determine cerebral function before and after VT ablation
기간: 24 hours after surgery
|
The use of the Mini-Mental Status Exam prior to the ablation will serve as a reference point and will be repeated 24 hours post exam.
|
24 hours after surgery
|
공동 작업자 및 조사자
수사관
- 수석 연구원: Dhanunjaya Lakkireddy, MD, FACC, University of Kansas Medical Center
연구 기록 날짜
연구 주요 날짜
연구 시작
기본 완료 (실제)
연구 완료 (실제)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (추정)
연구 기록 업데이트
마지막 업데이트 게시됨 (추정)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .