Intensity Training and Cardiovascular Health in Colombian Adults (HIIT-Heart)
2016년 10월 24일 업데이트: Robinson Ramírez-Vélez, Universidad Santo Tomas
High Intensity Interval- vs Moderate Training on Biomarkers of Endothelial and Cardiovascular Health in Adults: Effect of Postprandial Period
Several studies have shown relationship between exercise intensity and improvement cardiometabolic health.
It has been suggested that high intensity interval training and also moderate training generate positive effects on metabolic risk factors.
For these reasons, it is necessary to clarify which type of training, is more effective to improve cardiometabolic health in latinamerican population.
연구 개요
상태
완전한
정황
연구 유형
중재적
등록 (실제)
30
단계
- 해당 없음
연락처 및 위치
이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.
연구 장소
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Bogotá, 콜롬비아
- Robinson Ramírez Vélez Ph.D
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참여기준
연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.
자격 기준
공부할 수 있는 나이
20년 (성인)
건강한 자원 봉사자를 받아들입니다
예
연구 대상 성별
모두
설명
Inclusion Criteria:
- Written informed consent.
- Interested in improving health and fitness.
Exclusion Criteria:
- Systemic infections.
- Weight loss or gain of >10% of body weight in the past 6 months for any reason.
- Currently taking medication that suppresses or stimulates appetite.
- Uncontrolled hypertension: systolic blood pressure 160 mm Hg or diastolic blood pressure 95 mm Hg on treatment.
- Gastrointestinal disease, including self-reported chronic hepatitis or cirrhosis, any episode of alcoholic hepatitis or alcoholic pancreatitis within past year inflammatory bowel disease requiring treatment in the past year, recent or significant abdominal surgery (e.g., gastrectomy).
- Asthma.
- Diagnosed diabetes (type 1 or 2), fasting impaired glucose tolerance (blood glucose 118 mg/dL), or use of any anti-diabetic medications.
- Currently taking antidepressant, steroid, or thyroid medication, unless dosage is stable (no change for 6 months).
- Any active use of illegal or illicit drugs.
- Current exerciser (>30 min organized exercise per week).
- Indication of unsuitability of current health for exercise protocol (PARQ).
- Any other conditions which, in opinion of the investigators, would adversely affect the conduct of the trial.
공부 계획
이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 방지
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 하나의
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
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실험적: High Intensity Interval Training
Walking on a treadmill 4min at 80-90% peak heart rate and recovery 4 min at 65% peak heart rate until expenditure of 300 kcal until the end of training.
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Exercise will be performed at three sessions per week.
All sessions will be supervised by a trained health or exercise professional.
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활성 비교기: Moderate Intensity Interval Training
Walking on a treadmill at 60-80% peak heart rate until expenditure of 300 kcal until the end of training.
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Exercise will be performed at three sessions per week.
All sessions will be supervised by a trained health or exercise professional.
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Change from Baseline in endothelial function as measured by flow-mediated vasodilation (FMD)
기간: Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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FMD will be measured using the guidelines reported by Corretti et al.
The diameter of the brachial artery will be assessed using a high-resolution ultrasound device (Siemens SG-60, USA), equipped with a 7.5 MHz linear array transducer
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Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Change from Baseline in LDL Cholesterol
기간: Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Change from Baseline in HDL Cholesterol
기간: Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Change from Baseline in Triglycerides
기간: Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Change from Baseline in Glucose
기간: Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Change from Baseline in Heart rate variability
기간: Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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HRV will be performed according to current recommendations by European Society of Cardiology using an evaluated share-ware
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Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Aortic pulse wave velocity (PWVao)
기간: Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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PWVao (m s-1) will be performed within 3 to 4 minutes with the oscillometric, occlusive device, the Arteriograph.
The measurement will be taken in a supine position and were accepted if the quality indicator of the recordings was within the acceptable range (i.e., if the standard deviation [SD] of the beat-to-beat measured PWVao values was less than 1.1 m/sec).
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Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Change from Baseline in muscular fitness
기간: Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Muscular fitness (MF) will be assessed using handgrip test (maximum handgrip strength assessment) using a standard adjustable handle analogue handgrip dynamometer T-18 TKK SMEDLY III®
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Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Change from Baseline in Flexibility using the sit and reach test
기간: Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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It will be determined using a maximum treadmill exercise test (Precor TRM 885, Italy) following the modified Balke protocol
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Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Change from Baseline in peak uptake of volume of oxygen
기간: Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Change from Baseline in Blood Pressure
기간: Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Change from Baseline in Body Mass Index
기간: Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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BMI will be calculated as the body weight in kilograms divided by the square of the height in meters.
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Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Change from Baseline in Body Mass
기간: Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Change from Baseline in Quality & satisfaction with life by SF Community - short-form survey (SF-12™) Colombian version
기간: Baseline and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Baseline and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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Augmentation index (AIx)
기간: Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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AIx (%) will be performed within 3 to 4 minutes with the oscillometric, occlusive device, the Arteriograph.
The measurement will be taken in a supine position and were accepted if the quality indicator of the recordings was within the acceptable range (i.e., if the standard deviation [SD] of the beat-to-beat measured AIx values was less than 1.1 m/sec).
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Baseline, 2 and 12 weeks immediately after the interventions ends, preceding an 'unhealthy' meal.
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공동 작업자 및 조사자
여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.
수사관
- 연구 책임자: Robinson Ramírez Vélez, Ph.D, Universidad del Rosario
간행물 및 유용한 링크
연구에 대한 정보 입력을 담당하는 사람이 자발적으로 이러한 간행물을 제공합니다. 이것은 연구와 관련된 모든 것에 관한 것일 수 있습니다.
일반 간행물
- Ramirez-Velez R, Tordecilla-Sanders A, Tellez-T LA, Camelo-Prieto D, Hernandez-Quinonez PA, Correa-Bautista JE, Garcia-Hermoso A, Ramirez-Campillo R, Izquierdo M. Effect of Moderate- Versus High-Intensity Interval Exercise Training on Heart Rate Variability Parameters in Inactive Latin-American Adults: A Randomized Clinical Trial. J Strength Cond Res. 2020 Dec;34(12):3403-3415. doi: 10.1519/JSC.0000000000001833.
- Ramirez-Velez R, Hernandez-Quinones PA, Tordecilla-Sanders A, Alvarez C, Ramirez-Campillo R, Izquierdo M, Correa-Bautista JE, Garcia-Hermoso A, Garcia RG. Effectiveness of HIIT compared to moderate continuous training in improving vascular parameters in inactive adults. Lipids Health Dis. 2019 Feb 4;18(1):42. doi: 10.1186/s12944-019-0981-z.
- Ramirez-Velez R, Correa-Rodriguez M, Tordecilla-Sanders A, Aya-Aldana V, Izquierdo M, Correa-Bautista JE, Alvarez C, Garcia-Hermoso A. Exercise and postprandial lipemia: effects on vascular health in inactive adults. Lipids Health Dis. 2018 Apr 3;17(1):69. doi: 10.1186/s12944-018-0719-3.
- Ramirez-Velez R, Tordecilla-Sanders A, Tellez-T LA, Camelo-Prieto D, Hernandez-Quinonez PA, Correa-Bautista JE, Garcia-Hermoso A, Ramirez-Campillo R, Izquierdo M. Similar cardiometabolic effects of high- and moderate-intensity training among apparently healthy inactive adults: a randomized clinical trial. J Transl Med. 2017 May 30;15(1):118. doi: 10.1186/s12967-017-1216-6. Erratum In: J Transl Med. 2017 Jun 13;15(1):136.
연구 기록 날짜
이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.
연구 주요 날짜
연구 시작
2015년 6월 1일
기본 완료 (실제)
2016년 10월 1일
연구 완료 (실제)
2016년 10월 1일
연구 등록 날짜
최초 제출
2016년 3월 23일
QC 기준을 충족하는 최초 제출
2016년 4월 8일
처음 게시됨 (추정)
2016년 4월 14일
연구 기록 업데이트
마지막 업데이트 게시됨 (추정)
2016년 10월 25일
QC 기준을 충족하는 마지막 업데이트 제출
2016년 10월 24일
마지막으로 확인됨
2016년 10월 1일
추가 정보
이 연구와 관련된 용어
추가 관련 MeSH 약관
기타 연구 ID 번호
- 01-1802-2013
개별 참가자 데이터(IPD) 계획
개별 참가자 데이터(IPD)를 공유할 계획입니까?
아니요
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .
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