이 페이지는 자동 번역되었으며 번역의 정확성을 보장하지 않습니다. 참조하십시오 영문판 원본 텍스트의 경우.

코호트의 만성 질환 헌법의 이동성 장애 평가 (EVALMOB)

2026년 11월 2일 업데이트: University Hospital, Clermont-Ferrand

Chronic illness is a public health issue and mobility loss is frequent in this population. Among its' multiple physical and psychological consequences, increased mortality and cardiovascular morbidity seem the main concern. Therefore, the exploration of locomotor deficiencies, physical capacities and metabolism of patients with chronic illnesses constitutes a major challenge both for the treatment of causal pathologies, as well as for evaluating the impact of therapeutic interventions, the benefit of which will be an improvement in physical capacities and ultimately mobility. In view of the hypothesis of an increase in the prevalence of mobility disorders in this population, this approach is part of a logic of screening and improving the effectiveness of the care of these patients with a multidisciplinary evaluation of individual risks. The EVALMOB protocol was designed in order to try to determine a standard profile of "dysmobility" in patients with chronic illness

연구 개요

상세 설명

We propose to constitute a prospective cohort of subjects carrying chronic disease. The objective is to explore all the different components of mobility (balance, muscle force, body composition, walking ability, metabolism, etc.), to assess their impact on the functional capacity of individuals and to identify their potential interactions. Processing this data could ultimately allow the development of a model to determine a composite standard profile of "dysmobility" in patients with chronic disease.

In the present protocol, parameters will be measured on five occasions (at inclusion, at 6 months from the inclusion day, at 1,2 and 5 year(s) from the inclusion day). All tests will be performed on the same day. New assessments will be done on the same principle as the initial evaluation.

Statistical analyses will be carried out using Stata software (version 13, StataCorp, College Station, USA). Data will be described by frequencies and percentages for categorical variables and by means and standard deviation (or median and interquartile range if data are not normally distributed) for continuous variables. The normality of continuous data will be assessed graphically and using the Shapiro-Wilk test. The main analysis will consist in determining patient profiles regarding their mobility. Clustering-type approaches (supervised or not) will be proposed: k-means, vector machine support, machine learning, factor analysis. For example, factor analyses on mixed data will allow the main components of mobility to be characterized. They can be followed by an ascending hierarchical classification in order to determine homogeneous groups of patients.

These groups will be described and compared on the main criteria evaluated using standard statistical tests: chi2 test (or Fisher's exact test if applicable) for the categorical criteria and using an analysis of variance (or Kruskal-Wallis if data are not normally distributed) for continuous criteria. The main analysis will be broken down more specifically for each of the pathologies considered. In addition, the sensitivity to change will be assessed in each pathology and for each assessment criterion. The search for factors related to the evolution of the different criteria will be carried out using usual tests and mixed multivariate models (logistics for categorical / linear criteria for continuous criteria) considering the subject as a random effect, and adjusting on the time criteria (inclusion / follow-up) and the criteria highlighted in the univariate analyses and in light of the elements reported in the literature. A sensitivity analysis will be proposed in order to study the statistical nature of the missing data and to propose, if necessary, the most suitable method of imputing the data: multiple imputation, maximum bias or LOCF in the case of longitudinal data.

연구 유형

중재적

등록 (추정된)

5000

단계

  • 해당 없음

연락처 및 위치

이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.

연구 연락처

연구 장소

참여기준

연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.

자격 기준

공부할 수 있는 나이

18년 (성인, 고령자)

건강한 자원 봉사자를 받아들입니다

아니

연구 대상 성별

모두

설명

Inclusion Criteria:

  • Man or woman aged 18 to 90.
  • Patients with chronic pathology contributing to impaired mobility.
  • Volunteers who have given their written consent.
  • Affiliated to French health care system (for France)

Exclusion Criteria:

  • Patients suffering from progressive psychiatric pathologies (active psychosis, hallucinations, etc.) or the presence of another serious unstabilized pathology (decompensated heart failure, progressive terminal cancer, etc.).
  • People with poorly controlled or unstable cardiovascular disease.
  • Major osteoarticular or neurological problems completely preventing the proper performance of the various tests.
  • Non-autonomous patient
  • Persons under guardianship, curatorship, deprived of liberty or safeguarding justice.
  • People excluded from another study.
  • Pregnant or lactating women.

공부 계획

이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.

연구는 어떻게 설계됩니까?

디자인 세부사항

  • 주 목적: 특수 증상
  • 할당: 해당 없음
  • 중재 모델: 단일 그룹 할당
  • 마스킹: 없음(오픈 라벨)

무기와 개입

참가자 그룹 / 팔
개입 / 치료
실험적: Cohort 1

Participants will be involved in a long-term evaluation program combining, body composition measures, physical tests as well as self-administered questionnaires. Participants will be followed for 5 years with evaluations taking place at inclusion, 6 months, at 1, 2 and 5 years

Firstly, volunteers will be invited to complete online questionnaires on a secure platform. The mobility assessment will be carried out initially (t1) and up to a maximum of 4 times (t1 to t4) as part of a day hospitalization. Questionnaires will be diverse (SF36, KOOS, HOOS, BROCKER, MNA, TAMPA, etc.) in order to assess several aspects that compose mobility.

Physical evaluations will include various validated tests (isokinetic strength measure, TUG, 6MWT, Berg Balance Scale, etc.)

연구는 무엇을 측정합니까?

주요 결과 측정

결과 측정
측정값 설명
기간
dismobility score calculated from the results reported in secondary outcomes
기간: Day 0

The main objective being to determine patient profiles with regard to "dysmobility", all the criteria detailed as secondary outcomes will be considered for the definition of the profiles

Day 0
dismobility score calculated from the results reported in secondary outcomes
기간: Month 6

The main objective being to determine patient profiles with regard to "dysmobility", all the criteria detailed as secondary outcomes will be considered for the definition of the profiles

Month 6
dismobility score calculated from the results reported in secondary outcomes
기간: Year 1

The main objective being to determine patient profiles with regard to "dysmobility", all the criteria detailed as secondary outcomes will be considered for the definition of the profiles

Year 1
dismobility score calculated from the results reported in secondary outcomes
기간: Year 2

The main objective being to determine patient profiles with regard to "dysmobility", all the criteria detailed as secondary outcomes will be considered for the definition of the profiles

Year 2
dismobility score calculated from the results reported in secondary outcomes
기간: Year 5

The main objective being to determine patient profiles with regard to "dysmobility", all the criteria detailed as secondary outcomes will be considered for the definition of the profiles

Year 5

2차 결과 측정

결과 측정
측정값 설명
기간
The main objective being to determine patient profiles with regard to "dysmobility", all the criteria detailed as secondary outcomes will be considered for the definition of the profiles
기간: Day 0

Demographics information will be obtained using a single questionnaire including questions on age, gender, qualification, personal work status, ethnicity, life and occupational events.

Day 0
Weight (Kg).
기간: Day 0

Weight will be measured with the medical body weight scale SECA® and according to the ISAK recommendations.

Day 0
Weight (Kg).
기간: Month 6

Weight will be measured with the medical body weight scale SECA® and according to the ISAK recommendations.

Month 6
Weight (Kg).
기간: Year 1

Weight will be measured with the medical body weight scale SECA® and according to the ISAK recommendations.

Year 1
Weight (Kg).
기간: Year 2

Weight will be measured with the medical body weight scale SECA® and according to the ISAK recommendations.

Year 2
Weight (Kg).
기간: Year 5

Weight will be measured with the medical body weight scale SECA® and according to the ISAK recommendations.

Year 5
Height (cm).
기간: Day 0

Height will be measured with a wall mounted tape measure and according to the ISAK recommendations

Day 0
Height (cm).
기간: Month 6

Height will be measured with a wall mounted tape measure and according to the ISAK recommendations

Month 6
Height (cm).
기간: Year 1

Height will be measured with a wall mounted tape measure and according to the ISAK recommendations

Year 1
Height (cm).
기간: Year 2

Height will be measured with a wall mounted tape measure and according to the ISAK recommendations

Year 2
Height (cm).
기간: Year 5

Height will be measured with a wall mounted tape measure and according to the ISAK recommendations

Year 5
Body fat percentage (%).
기간: Day 0

Body fat percentage will be measured with the Harpenden skinfold caliper by measuring skinfold thickness in four different sites (triceps; biceps, suprailiac, subscapular).

Day 0
Body fat percentage (%).
기간: Month 6

Body fat percentage will be measured with the Harpenden skinfold caliper by measuring skinfold thickness in four different sites (triceps; biceps, suprailiac, subscapular).

Month 6
Body fat percentage (%).
기간: Year 1

Body fat percentage will be measured with the Harpenden skinfold caliper by measuring skinfold thickness in four different sites (triceps; biceps, suprailiac, subscapular).

Year 1
Body fat percentage (%).
기간: Year 2

Body fat percentage will be measured with the Harpenden skinfold caliper by measuring skinfold thickness in four different sites (triceps; biceps, suprailiac, subscapular).

Year 2
Body fat percentage (%).
기간: Year 5

Body fat percentage will be measured with the Harpenden skinfold caliper by measuring skinfold thickness in four different sites (triceps; biceps, suprailiac, subscapular).

Year 5
Waist circumference (cm).
기간: Day 0

Waist circumference will be measured with a medical body tape measure and according to the ISAK recommendations

Day 0
Waist circumference (cm).
기간: Month 5

Waist circumference will be measured with a medical body tape measure and according to the ISAK recommendations

Month 5
Waist circumference (cm).
기간: Year 1

Waist circumference will be measured with a medical body tape measure and according to the ISAK recommendations

Year 1
Waist circumference (cm).
기간: Year 2

Waist circumference will be measured with a medical body tape measure and according to the ISAK recommendations

Year 2
Waist circumference (cm).
기간: Year 5

Waist circumference will be measured with a medical body tape measure and according to the ISAK recommendations

Year 5
Hip circumference (cm).
기간: Day 0

Hip circumference will be measured with a medical body tape measure and according to the ISAK recommendations.

Day 0
Hip circumference (cm).
기간: Month 6

Hip circumference will be measured with a medical body tape measure and according to the ISAK recommendations.

Month 6
Hip circumference (cm).
기간: Year 1

Hip circumference will be measured with a medical body tape measure and according to the ISAK recommendations.

Year 1
Hip circumference (cm).
기간: Year 2

Hip circumference will be measured with a medical body tape measure and according to the ISAK recommendations.

Year 2
Hip circumference (cm).
기간: Year 5

Hip circumference will be measured with a medical body tape measure and according to the ISAK recommendations.

Year 5
Brachial circumference (cm).
기간: Day 0

Brachial circumference will be measured with a medical body tape measure and according to the ISAK recommendations.

Day 0
Brachial circumference (cm).
기간: Month 6

Brachial circumference will be measured with a medical body tape measure and according to the ISAK recommendations.

Month 6
Brachial circumference (cm).
기간: Year 1

Brachial circumference will be measured with a medical body tape measure and according to the ISAK recommendations.

Year 1
Brachial circumference (cm).
기간: Year 2

Brachial circumference will be measured with a medical body tape measure and according to the ISAK recommendations.

Year 2
Brachial circumference (cm).
기간: Year 5

Brachial circumference will be measured with a medical body tape measure and according to the ISAK recommendations.

Year 5
Calf circumference (cm).
기간: Day 0

Calf circumference will be measured with a medical body tape measure and according to the ISAK recommendations

Day 0
Calf circumference (cm).
기간: Month 6

Calf circumference will be measured with a medical body tape measure and according to the ISAK recommendations

Month 6
Calf circumference (cm).
기간: Year 1

Calf circumference will be measured with a medical body tape measure and according to the ISAK recommendations

Year 1
Calf circumference (cm).
기간: Year 2

Calf circumference will be measured with a medical body tape measure and according to the ISAK recommendations

Year 2
Calf circumference (cm).
기간: Year 5

Calf circumference will be measured with a medical body tape measure and according to the ISAK recommendations

Year 5
Body Mass Index (Kg/m²).
기간: Day 0

BMI will be calculated (weight in kilograms divided by height in meters squared).

Day 0
Body Mass Index (Kg/m²).
기간: Month 6

BMI will be calculated (weight in kilograms divided by height in meters squared).

Month 6
Body Mass Index (Kg/m²).
기간: Year 1

BMI will be calculated (weight in kilograms divided by height in meters squared).

Year 1
Body Mass Index (Kg/m²).
기간: Year 2

BMI will be calculated (weight in kilograms divided by height in meters squared).

Year 2
Body Mass Index (Kg/m²).
기간: Year 5

BMI will be calculated (weight in kilograms divided by height in meters squared).

Year 5
Body composition
기간: Day 0

Body composition (muscle and fat) will be measured using he Bodystat® Impedance-meter.

Day 0
Body composition
기간: Month 6

Body composition (muscle and fat) will be measured using he Bodystat® Impedance-meter.

Month 6
Body composition
기간: Year 1

Body composition (muscle and fat) will be measured using he Bodystat® Impedance-meter.

Year 1
Body composition
기간: Year 2

Body composition (muscle and fat) will be measured using he Bodystat® Impedance-meter.

Year 2
Body composition
기간: Year 5

Body composition (muscle and fat) will be measured using he Bodystat® Impedance-meter.

Year 5
T-score (DS).
기간: DAy 0

- Description: T-score will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

DAy 0
T-score (DS).
기간: Month 6

- Description: T-score will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Month 6
T-score (DS).
기간: Year 1

- Description: T-score will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 1
T-score (DS).
기간: Year 2

- Description: T-score will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 2
T-score (DS).
기간: Year 5

- Description: T-score will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 5
Z-score (DS).
기간: Day 0

Z-score will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer

Day 0
Z-score (DS).
기간: Month 6

Z-score will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer

Month 6
Z-score (DS).
기간: Year 1

Z-score will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer

Year 1
Z-score (DS).
기간: Year 2

Z-score will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer

Year 2
Z-score (DS).
기간: Year 5

Z-score will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer

Year 5
Fat mass
기간: Day 0

Fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Day 0
Fat mass
기간: Month 6

Fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Month 6
Fat mass
기간: Year 1

Fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 1
Fat mass
기간: Year 2

Fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 2
Fat mass
기간: Year 5

Fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 5
Fat-free mass (%).
기간: Day 0

: Fat free mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Day 0
Fat-free mass (%).
기간: Month 6

: Fat free mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Month 6
Fat-free mass (%).
기간: Year 1

: Fat free mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 1
Fat-free mass (%).
기간: Year 2

: Fat free mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 2
Fat-free mass (%).
기간: Year 5

: Fat free mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 5
Fat mas index (Kg/m²).
기간: Day 0

Fat mas index will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Day 0
Fat mas index (Kg/m²).
기간: Month 6

Fat mas index will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Month 6
Fat mas index (Kg/m²).
기간: Year 1

Fat mas index will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 1
Fat mas index (Kg/m²).
기간: Year 2

Fat mas index will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 2
Fat mas index (Kg/m²).
기간: Year 5

Fat mas index will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 5
Ratio of android to gynoid fat mass.
기간: Day 0

Ratio of android to gynoid fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer

Day 0
Ratio of android to gynoid fat mass.
기간: Month 6

Ratio of android to gynoid fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer

Month 6
Ratio of android to gynoid fat mass.
기간: Year 1

Ratio of android to gynoid fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer

Year 1
Ratio of android to gynoid fat mass.
기간: Year 2

Ratio of android to gynoid fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer

Year 2
Ratio of android to gynoid fat mass.
기간: Year 5

Ratio of android to gynoid fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer

Year 5
Visceral adipose tissue (Kg).
기간: Day 0

Visceral fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Day 0
Visceral adipose tissue (Kg).
기간: Month 6

Visceral fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Month 6
Visceral adipose tissue (Kg).
기간: Year 1

Visceral fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 1
Visceral adipose tissue (Kg).
기간: Year 2

Visceral fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 2
Visceral adipose tissue (Kg).
기간: Year 5

Visceral fat mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 5
Fat-free mass index (kg/m²).
기간: Day 0

: Fat-free mass index will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Day 0
Fat-free mass index (kg/m²).
기간: Month 6

: Fat-free mass index will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Month 6
Fat-free mass index (kg/m²).
기간: Year 1

: Fat-free mass index will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 1
Fat-free mass index (kg/m²).
기간: Year 2

: Fat-free mass index will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 2
Fat-free mass index (kg/m²).
기간: Year 5

: Fat-free mass index will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 5
Appendicular fat-free mass index (Kg/m²).
기간: Day 0

Appendicular fat-free mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Day 0
Appendicular fat-free mass index (Kg/m²).
기간: Month 6

Appendicular fat-free mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Month 6
Appendicular fat-free mass index (Kg/m²).
기간: Year 1

Appendicular fat-free mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 1
Appendicular fat-free mass index (Kg/m²).
기간: Year 2

Appendicular fat-free mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 2
Appendicular fat-free mass index (Kg/m²).
기간: Year 5

Appendicular fat-free mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 5
Bone mass (Kg)
기간: Day 0

- Description: Bone mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Day 0
Bone mass (Kg)
기간: Month 6

- Description: Bone mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Month 6
Bone mass (Kg)
기간: Year 1

- Description: Bone mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 1
Bone mass (Kg)
기간: Year 2

- Description: Bone mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 2
Bone mass (Kg)
기간: Year 5

- Description: Bone mass will be measured with the Hologic QDR 4500A dual-energy X-ray absorptiometer.

Year 5
Daily caloric intake (Kcal/24h).
기간: Day 0

Daily caloric intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Day 0
Daily caloric intake (Kcal/24h).
기간: Month 6

Daily caloric intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Month 6
Daily caloric intake (Kcal/24h).
기간: Year 1

Daily caloric intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Year 1
Daily caloric intake (Kcal/24h).
기간: Year 2

Daily caloric intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Year 2
Daily caloric intake (Kcal/24h).
기간: Year 5

Daily caloric intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Year 5
Daily protein intake (in g and as a percentage of total caloric intake).
기간: Day 0

Daily protein intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Day 0
Daily protein intake (in g and as a percentage of total caloric intake).
기간: Month 6

Daily protein intake (in g and as a percentage of total caloric intake).

Month 6
Daily protein intake (in g and as a percentage of total caloric intake).
기간: Year 1

Daily protein intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Year 1
Daily protein intake (in g and as a percentage of total caloric intake).
기간: Year 2

Daily protein intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Year 2
Daily protein intake (in g and as a percentage of total caloric intake).
기간: Year 5

Daily protein intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Year 5
Daily carbohydrate intake (in g and as a percentage of total caloric intake).
기간: Day 0

Daily carbohydrate intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Day 0
Daily carbohydrate intake (in g and as a percentage of total caloric intake).
기간: Month 6

Daily carbohydrate intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Month 6
Daily carbohydrate intake (in g and as a percentage of total caloric intake).
기간: Year 1

Daily carbohydrate intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Year 1
Daily carbohydrate intake (in g and as a percentage of total caloric intake).
기간: Year 2

Daily carbohydrate intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Year 2
Daily carbohydrate intake (in g and as a percentage of total caloric intake).
기간: Year 5

Daily carbohydrate intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Year 5
Daily fat intake (in g and as a percentage of total caloric intake).
기간: Day 0

Daily fat intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Day 0
Daily fat intake (in g and as a percentage of total caloric intake).
기간: Month 6

Daily fat intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Month 6
Daily fat intake (in g and as a percentage of total caloric intake).
기간: Year 1

Daily fat intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Year 1
Daily fat intake (in g and as a percentage of total caloric intake).
기간: Year 2

Daily fat intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Year 2
Daily fat intake (in g and as a percentage of total caloric intake).
기간: Year 5

Daily fat intake will be estimated with a 24-hour (all foods and beverages consumed by the respondent in the past 24 hours).

Year 5
Nutritional status assessment
기간: Day 0

Nutritional status assessment will be assessed with the Mini Nutritional Assessment Questionnaire.

Day 0
Nutritional status assessment
기간: Month 6

Nutritional status assessment will be assessed with the Mini Nutritional Assessment Questionnaire.

Month 6
Nutritional status assessment
기간: Year 1

Nutritional status assessment will be assessed with the Mini Nutritional Assessment Questionnaire.

Year 1
Nutritional status assessment
기간: Year 2

Nutritional status assessment will be assessed with the Mini Nutritional Assessment Questionnaire.

Year 2
Nutritional status assessment
기간: Year 5

Nutritional status assessment will be assessed with the Mini Nutritional Assessment Questionnaire.

Year 5
Risk of undernutrition.
기간: Day 0

Risk of undernutrition will be assessed with the Brocker Questionnaire

Day 0
Risk of undernutrition.
기간: Month 6

Risk of undernutrition will be assessed with the Brocker Questionnaire

Month 6
Risk of undernutrition.
기간: Year 1

Risk of undernutrition will be assessed with the Brocker Questionnaire

Year 1
Risk of undernutrition.
기간: Year 2

Risk of undernutrition will be assessed with the Brocker Questionnaire

Year 2
Risk of undernutrition.
기간: Year 5

Risk of undernutrition will be assessed with the Brocker Questionnaire

Year 5
Basic biology.
기간: Day 0

: Basic biology will be measured using endocrine assays (fasting blood glucose, HbA1c, HDL-c and LDL-c, TG, CPK)

Day 0
Basic biology.
기간: Month 6

: Basic biology will be measured using endocrine assays (fasting blood glucose, HbA1c, HDL-c and LDL-c, TG, CPK)

Month 6
Basic biology.
기간: Year 1

: Basic biology will be measured using endocrine assays (fasting blood glucose, HbA1c, HDL-c and LDL-c, TG, CPK)

Year 1
Basic biology.
기간: Year 2

: Basic biology will be measured using endocrine assays (fasting blood glucose, HbA1c, HDL-c and LDL-c, TG, CPK)

Year 2
Basic biology.
기간: Year 5

: Basic biology will be measured using endocrine assays (fasting blood glucose, HbA1c, HDL-c and LDL-c, TG, CPK)

Year 5
Maximum voluntary isometric strength of the quadriceps muscles at 45° (Nm).
기간: Day 0

: Maximum voluntary isometric strength of the quadriceps muscles will be measured with the HUMA® /NORM™ device.

Day 0
Maximum voluntary isometric strength of the quadriceps muscles at 45° (Nm).
기간: Month 6

: Maximum voluntary isometric strength of the quadriceps muscles will be measured with the HUMA® /NORM™ device.

Month 6
Maximum voluntary isometric strength of the quadriceps muscles at 45° (Nm).
기간: Year 1

: Maximum voluntary isometric strength of the quadriceps muscles will be measured with the HUMA® /NORM™ device.

Year 1
Maximum voluntary isometric strength of the quadriceps muscles at 45° (Nm).
기간: Year 2

: Maximum voluntary isometric strength of the quadriceps muscles will be measured with the HUMA® /NORM™ device.

Year 2
Maximum voluntary isometric strength of the quadriceps muscles at 45° (Nm).
기간: Year 5

: Maximum voluntary isometric strength of the quadriceps muscles will be measured with the HUMA® /NORM™ device.

Year 5
Maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s (Nm).
기간: Day 0

- Description: Maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s will be measured with the HUMA® /NORM™ device.

Day 0
Maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s (Nm).
기간: Month 6

- Description: Maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s will be measured with the HUMA® /NORM™ device.

Month 6
Maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s (Nm).
기간: Year 1

- Description: Maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s will be measured with the HUMA® /NORM™ device.

Year 1
Maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s (Nm).
기간: Year 2

- Description: Maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s will be measured with the HUMA® /NORM™ device.

Year 2
Maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s (Nm).
기간: Year 5

- Description: Maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s will be measured with the HUMA® /NORM™ device.

Year 5
Maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s (Nm).
기간: Day 0

Maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s will be measured with the HUMA® /NORM™ device.

Day 0
Maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s (Nm).
기간: Month 6

Maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s will be measured with the HUMA® /NORM™ device.

Month 6
Maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s (Nm).
기간: Year 1

Maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s will be measured with the HUMA® /NORM™ device.

Year 1
Maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s (Nm).
기간: Year 2

Maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s will be measured with the HUMA® /NORM™ device.

Year 2
Maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s (Nm).
기간: Year 5

Maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s will be measured with the HUMA® /NORM™ device.

Year 5
Maximum voluntary isokinetic strength of the quadriceps muscles at 30°/s (eccentric contraction) (Nm).
기간: Day 0

Maximum voluntary isokinetic strength of the quadriceps muscles at 30°/s will be measured with the HUMA® /NORM™ device.

Day 0
Maximum voluntary isokinetic strength of the quadriceps muscles at 30°/s (eccentric contraction) (Nm).
기간: Month 6

Maximum voluntary isokinetic strength of the quadriceps muscles at 30°/s will be measured with the HUMA® /NORM™ device.

Month 6
Maximum voluntary isokinetic strength of the quadriceps muscles at 30°/s (eccentric contraction) (Nm).
기간: Year 1

Maximum voluntary isokinetic strength of the quadriceps muscles at 30°/s will be measured with the HUMA® /NORM™ device.

Year 1
Maximum voluntary isokinetic strength of the quadriceps muscles at 30°/s (eccentric contraction) (Nm).
기간: Year 2

Maximum voluntary isokinetic strength of the quadriceps muscles at 30°/s will be measured with the HUMA® /NORM™ device.

Year 2
Maximum voluntary isokinetic strength of the quadriceps muscles at 30°/s (eccentric contraction) (Nm).
기간: Year 5

Maximum voluntary isokinetic strength of the quadriceps muscles at 30°/s will be measured with the HUMA® /NORM™ device.

Year 5
Maximum voluntary isokinetic strength of the hamstring muscles at 60°/s (Nm).
기간: Day 0

Maximum voluntary isokinetic strength of the hamstring muscles at 60°/s will be measured with the HUMA® /NORM™ device.

Day 0
Maximum voluntary isokinetic strength of the hamstring muscles at 60°/s (Nm).
기간: Month 6

Maximum voluntary isokinetic strength of the hamstring muscles at 60°/s will be measured with the HUMA® /NORM™ device.

Month 6
Maximum voluntary isokinetic strength of the hamstring muscles at 60°/s (Nm).
기간: Year 1

Maximum voluntary isokinetic strength of the hamstring muscles at 60°/s will be measured with the HUMA® /NORM™ device.

Year 1
Maximum voluntary isokinetic strength of the hamstring muscles at 60°/s (Nm).
기간: Year 2

Maximum voluntary isokinetic strength of the hamstring muscles at 60°/s will be measured with the HUMA® /NORM™ device.

Year 2
Maximum voluntary isokinetic strength of the hamstring muscles at 60°/s (Nm).
기간: Year 5

Maximum voluntary isokinetic strength of the hamstring muscles at 60°/s will be measured with the HUMA® /NORM™ device.

Year 5
Maximum voluntary isokinetic strength of the hamstring muscles at 240°/s (Nm).
기간: Day 0

- Description: Maximum voluntary isokinetic strength of the hamstring muscles at 240°/s will be measured with the HUMA® /NORM™ device.

Day 0
Maximum voluntary isokinetic strength of the hamstring muscles at 240°/s (Nm).
기간: Month 6

- Description: Maximum voluntary isokinetic strength of the hamstring muscles at 240°/s will be measured with the HUMA® /NORM™ device.

Month 6
Maximum voluntary isokinetic strength of the hamstring muscles at 240°/s (Nm).
기간: Year 1

- Description: Maximum voluntary isokinetic strength of the hamstring muscles at 240°/s will be measured with the HUMA® /NORM™ device.

Year 1
Maximum voluntary isokinetic strength of the hamstring muscles at 240°/s (Nm).
기간: Year 2

- Description: Maximum voluntary isokinetic strength of the hamstring muscles at 240°/s will be measured with the HUMA® /NORM™ device.

Year 2
Maximum voluntary isokinetic strength of the hamstring muscles at 240°/s (Nm).
기간: Year 5

- Description: Maximum voluntary isokinetic strength of the hamstring muscles at 240°/s will be measured with the HUMA® /NORM™ device.

Year 5
Maximum voluntary isokinetic strength of the hamstring muscles at 30°/s (eccentric contraction) (Nm).
기간: Day 0

Maximum voluntary isokinetic strength of the hamstring muscles at 30°/s will be measured with the HUMA® /NORM™ device.

Day 0
Maximum voluntary isokinetic strength of the hamstring muscles at 30°/s (eccentric contraction) (Nm).
기간: Month 6

Maximum voluntary isokinetic strength of the hamstring muscles at 30°/s will be measured with the HUMA® /NORM™ device.

Month 6
Maximum voluntary isokinetic strength of the hamstring muscles at 30°/s (eccentric contraction) (Nm).
기간: Year 1

Maximum voluntary isokinetic strength of the hamstring muscles at 30°/s will be measured with the HUMA® /NORM™ device.

Year 1
Maximum voluntary isokinetic strength of the hamstring muscles at 30°/s (eccentric contraction) (Nm).
기간: Year 2

Maximum voluntary isokinetic strength of the hamstring muscles at 30°/s will be measured with the HUMA® /NORM™ device.

Year 2
Maximum voluntary isokinetic strength of the hamstring muscles at 30°/s (eccentric contraction) (Nm).
기간: Year 5

Maximum voluntary isokinetic strength of the hamstring muscles at 30°/s will be measured with the HUMA® /NORM™ device.

Year 5
Endurance coefficient of the quadriceps muscles at 180°/s.
기간: Day 0

Endurance coefficient will be estimated as a Σ Peak torque ratio of the last 3 contractions on the first 3 at 180°/s with the HUMA® /NORM™ device.

Day 0
Endurance coefficient of the quadriceps muscles at 180°/s.
기간: Month 6

Endurance coefficient will be estimated as a Σ Peak torque ratio of the last 3 contractions on the first 3 at 180°/s with the HUMA® /NORM™ device.

Month 6
Endurance coefficient of the quadriceps muscles at 180°/s.
기간: Year 1

Endurance coefficient will be estimated as a Σ Peak torque ratio of the last 3 contractions on the first 3 at 180°/s with the HUMA® /NORM™ device.

Year 1
Endurance coefficient of the quadriceps muscles at 180°/s.
기간: Year 2

Endurance coefficient will be estimated as a Σ Peak torque ratio of the last 3 contractions on the first 3 at 180°/s with the HUMA® /NORM™ device.

Year 2
Endurance coefficient of the quadriceps muscles at 180°/s.
기간: Year 5

Endurance coefficient will be estimated as a Σ Peak torque ratio of the last 3 contractions on the first 3 at 180°/s with the HUMA® /NORM™ device.

Year 5
Endurance coefficient of the hamstring muscles at 180°/s.
기간: Day 0

Endurance coefficient will be estimated as a Σ Peak torque ratio of the last 3 contractions on the first 3 at 180°/s with the HUMA® /NORM™ device..

Day 0
Endurance coefficient of the hamstring muscles at 180°/s.
기간: Month 6

Endurance coefficient will be estimated as a Σ Peak torque ratio of the last 3 contractions on the first 3 at 180°/s with the HUMA® /NORM™ device..

Month 6
Endurance coefficient of the hamstring muscles at 180°/s.
기간: Year 1

Endurance coefficient will be estimated as a Σ Peak torque ratio of the last 3 contractions on the first 3 at 180°/s with the HUMA® /NORM™ device..

Year 1
Endurance coefficient of the hamstring muscles at 180°/s.
기간: Year 2

Endurance coefficient will be estimated as a Σ Peak torque ratio of the last 3 contractions on the first 3 at 180°/s with the HUMA® /NORM™ device..

Year 2
Endurance coefficient of the hamstring muscles at 180°/s.
기간: Year 5

Endurance coefficient will be estimated as a Σ Peak torque ratio of the last 3 contractions on the first 3 at 180°/s with the HUMA® /NORM™ device..

Year 5
Functional ratio
기간: Day 0

Functional ratio will be estimated by dividing the maximum voluntary isokinetic strength of the hamstring muscles at 60°/s with the maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s.

Day 0
Functional ratio
기간: Month 6

Functional ratio will be estimated by dividing the maximum voluntary isokinetic strength of the hamstring muscles at 60°/s with the maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s.

Month 6
Functional ratio
기간: Year 1

Functional ratio will be estimated by dividing the maximum voluntary isokinetic strength of the hamstring muscles at 60°/s with the maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s.

Year 1
Functional ratio
기간: Year 2

Functional ratio will be estimated by dividing the maximum voluntary isokinetic strength of the hamstring muscles at 60°/s with the maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s.

Year 2
Functional ratio
기간: Year 5

Functional ratio will be estimated by dividing the maximum voluntary isokinetic strength of the hamstring muscles at 60°/s with the maximum voluntary isokinetic strength of the quadriceps muscles at 60°/s.

Year 5
Mixed ratio
기간: Day 0

- Mixed ratio will be estimated by dividing the maximum voluntary isokinetic strength of the hamstring muscles at 30°/s (eccentric contraction) with the maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s Title: Maximum voluntary strength of the quadriceps muscles at 60°/s.

Day 0
Mixed ratio
기간: Month 6

- Mixed ratio will be estimated by dividing the maximum voluntary isokinetic strength of the hamstring muscles at 30°/s (eccentric contraction) with the maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s Title: Maximum voluntary strength of the quadriceps muscles at 60°/s.

Month 6
Mixed ratio
기간: Year 1

- Mixed ratio will be estimated by dividing the maximum voluntary isokinetic strength of the hamstring muscles at 30°/s (eccentric contraction) with the maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s Title: Maximum voluntary strength of the quadriceps muscles at 60°/s.

Year 1
Mixed ratio
기간: Year 2

- Mixed ratio will be estimated by dividing the maximum voluntary isokinetic strength of the hamstring muscles at 30°/s (eccentric contraction) with the maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s Title: Maximum voluntary strength of the quadriceps muscles at 60°/s.

Year 2
Mixed ratio
기간: Year 5

- Mixed ratio will be estimated by dividing the maximum voluntary isokinetic strength of the hamstring muscles at 30°/s (eccentric contraction) with the maximum voluntary isokinetic strength of the quadriceps muscles at 240°/s Title: Maximum voluntary strength of the quadriceps muscles at 60°/s.

Year 5
Maximum voluntary hand grip strength (Kg).
기간: Day 0

Maximum voluntary hand grip strength will be measured with the Jamar® hydraulic dynamometer and with the Baseline® pneumatic dynamometer.

Day 0
Maximum voluntary hand grip strength (Kg).
기간: Month 6

Maximum voluntary hand grip strength will be measured with the Jamar® hydraulic dynamometer and with the Baseline® pneumatic dynamometer.

Month 6
Maximum voluntary hand grip strength (Kg).
기간: Year 1

Maximum voluntary hand grip strength will be measured with the Jamar® hydraulic dynamometer and with the Baseline® pneumatic dynamometer.

Year 1
Maximum voluntary hand grip strength (Kg).
기간: Year 2

Maximum voluntary hand grip strength will be measured with the Jamar® hydraulic dynamometer and with the Baseline® pneumatic dynamometer.

Year 2
Maximum voluntary hand grip strength (Kg).
기간: Year 5

Maximum voluntary hand grip strength will be measured with the Jamar® hydraulic dynamometer and with the Baseline® pneumatic dynamometer.

Year 5
Maximum voluntary pinch strength (Kg).
기간: Day 0

Maximum voluntary pinch strength will be measured with the Baseline® pinch gauche test mechanical dynamometer.

Day 0
Maximum voluntary pinch strength (Kg).
기간: Month 6

Maximum voluntary pinch strength will be measured with the Baseline® pinch gauche test mechanical dynamometer.

Month 6
Maximum voluntary pinch strength (Kg).
기간: Year 1

Maximum voluntary pinch strength will be measured with the Baseline® pinch gauche test mechanical dynamometer.

Year 1
Maximum voluntary pinch strength (Kg).
기간: Year 2

Maximum voluntary pinch strength will be measured with the Baseline® pinch gauche test mechanical dynamometer.

Year 2
Maximum voluntary pinch strength (Kg).
기간: Year 5

Maximum voluntary pinch strength will be measured with the Baseline® pinch gauche test mechanical dynamometer.

Year 5
Hip passive joint range
기간: Day 0

Hip joint range will be measured with a medical goniometer.

Day 0
Hip passive joint range
기간: Month 6

Hip joint range will be measured with a medical goniometer.

Month 6
Hip passive joint range
기간: Year 1

Hip joint range will be measured with a medical goniometer.

Year 1
Hip passive joint range
기간: Year 2

Hip joint range will be measured with a medical goniometer.

Year 2
Hip passive joint range
기간: Year 5

Hip joint range will be measured with a medical goniometer.

Year 5
Knee passive joint range.
기간: Day 0

Knee joint range will be measured with a medical goniometer.

Day 0
Knee passive joint range.
기간: Month 6

Knee joint range will be measured with a medical goniometer.

Month 6
Knee passive joint range.
기간: Year 1

Knee joint range will be measured with a medical goniometer.

Year 1
Knee passive joint range.
기간: Year 2

Knee joint range will be measured with a medical goniometer.

Year 2
Knee passive joint range.
기간: Year 5

Knee joint range will be measured with a medical goniometer.

Year 5
Ankle passive joint range
기간: Day 0

Ankle joint range will be measured with a medical goniometer.

Day 0
Ankle passive joint range
기간: Month 6

Ankle joint range will be measured with a medical goniometer.

Month 6
Ankle passive joint range
기간: Year 1

Ankle joint range will be measured with a medical goniometer.

Year 1
Ankle passive joint range
기간: Year 2

Ankle joint range will be measured with a medical goniometer.

Year 2
Ankle passive joint range
기간: Year 5

Ankle joint range will be measured with a medical goniometer.

Year 5
Lower and upper limb muscle power assessment (MRC)
기간: Day 0

Lower and upper limb muscle power assessment will be performed by an experienced physician.

Day 0
Lower and upper limb muscle power assessment (MRC)
기간: Month 6

Lower and upper limb muscle power assessment will be performed by an experienced physician.

Month 6
Lower and upper limb muscle power assessment (MRC)
기간: Year 1

Lower and upper limb muscle power assessment will be performed by an experienced physician.

Year 1
Lower and upper limb muscle power assessment (MRC)
기간: Year 2

Lower and upper limb muscle power assessment will be performed by an experienced physician.

Year 2
Lower and upper limb muscle power assessment (MRC)
기간: Year 5

Lower and upper limb muscle power assessment will be performed by an experienced physician.

Year 5
Statokinesigram surface area (mm²)
기간: Day 0

Statokinesigram surface area will be measured with the STATIPRO® static posturography platform.

Day 0
Statokinesigram surface area (mm²)
기간: Month 6

Statokinesigram surface area will be measured with the STATIPRO® static posturography platform.

Month 6
Statokinesigram surface area (mm²)
기간: Year 1

Statokinesigram surface area will be measured with the STATIPRO® static posturography platform.

Year 1
Statokinesigram surface area (mm²)
기간: Year 2

Statokinesigram surface area will be measured with the STATIPRO® static posturography platform.

Year 2
Statokinesigram surface area (mm²)
기간: Year 5

Statokinesigram surface area will be measured with the STATIPRO® static posturography platform.

Year 5
Stabilogram length (mm).
기간: Day 0

Stabilogram length will be measured with the STATIPRO® static posturography platform

Day 0
Stabilogram length (mm).
기간: Month 6

Stabilogram length will be measured with the STATIPRO® static posturography platform

Month 6
Stabilogram length (mm).
기간: Year 1

Stabilogram length will be measured with the STATIPRO® static posturography platform

Year 1
Stabilogram length (mm).
기간: Year 2

Stabilogram length will be measured with the STATIPRO® static posturography platform

Year 2
Stabilogram length (mm).
기간: Year 5

Stabilogram length will be measured with the STATIPRO® static posturography platform

Year 5
Maximal deflection (forward, backward left and right).
기간: Day 0

Maximal deflection will be measured with the STATIPRO® static posturography platform.

Day 0
Maximal deflection (forward, backward left and right).
기간: Month 6

Maximal deflection will be measured with the STATIPRO® static posturography platform.

Month 6
Maximal deflection (forward, backward left and right).
기간: Year 1

Maximal deflection will be measured with the STATIPRO® static posturography platform.

Year 1
Maximal deflection (forward, backward left and right).
기간: Year 2

Maximal deflection will be measured with the STATIPRO® static posturography platform.

Year 2
Maximal deflection (forward, backward left and right).
기간: Year 5

Maximal deflection will be measured with the STATIPRO® static posturography platform.

Year 5
Velocity variations (mm/s).
기간: Day 0

: Velocity variations will be measured with the STATIPRO® static posturography platform.

Day 0
Velocity variations (mm/s).
기간: Month 6

: Velocity variations will be measured with the STATIPRO® static posturography platform.

Month 6
Velocity variations (mm/s).
기간: Year 1

: Velocity variations will be measured with the STATIPRO® static posturography platform.

Year 1
Velocity variations (mm/s).
기간: Year 2

: Velocity variations will be measured with the STATIPRO® static posturography platform.

Year 2
Velocity variations (mm/s).
기간: Year 5

: Velocity variations will be measured with the STATIPRO® static posturography platform.

Year 5
: Romberg ratio according to sway area
기간: Day 0

Romberg ratio will be measured with the STATIPRO® static posturography platform.

Day 0
: Romberg ratio according to sway area
기간: Month 6

Romberg ratio will be measured with the STATIPRO® static posturography platform.

Month 6
: Romberg ratio according to sway area
기간: Year 1

Romberg ratio will be measured with the STATIPRO® static posturography platform.

Year 1
: Romberg ratio according to sway area
기간: Year 2

Romberg ratio will be measured with the STATIPRO® static posturography platform.

Year 2
: Romberg ratio according to sway area
기간: Year 5

Romberg ratio will be measured with the STATIPRO® static posturography platform.

Year 5
Romberg ratio according to center of pressure path length
기간: Day 0

Romberg ratio will be measured with the STATIPRO® static posturography platform.

Day 0
Romberg ratio according to center of pressure path length
기간: Month 6

Romberg ratio will be measured with the STATIPRO® static posturography platform.

Month 6
Romberg ratio according to center of pressure path length
기간: Year 1

Romberg ratio will be measured with the STATIPRO® static posturography platform.

Year 1
Romberg ratio according to center of pressure path length
기간: Year 2

Romberg ratio will be measured with the STATIPRO® static posturography platform.

Year 2
Romberg ratio according to center of pressure path length
기간: Year 5

Romberg ratio will be measured with the STATIPRO® static posturography platform.

Year 5
: Plantar pressure ratio sway area.
기간: Day 0

Plantar pressure ratio sway area will be measured with the STATIPRO® static posturography platform.

Day 0
: Plantar pressure ratio sway area.
기간: Month 6

Plantar pressure ratio sway area will be measured with the STATIPRO® static posturography platform.

Month 6
: Plantar pressure ratio sway area.
기간: Year 1

Plantar pressure ratio sway area will be measured with the STATIPRO® static posturography platform.

Year 1
: Plantar pressure ratio sway area.
기간: Year 2

Plantar pressure ratio sway area will be measured with the STATIPRO® static posturography platform.

Year 2
: Plantar pressure ratio sway area.
기간: Year 5

Plantar pressure ratio sway area will be measured with the STATIPRO® static posturography platform.

Year 5
Plantar pressure ratio length.
기간: Day 0

Plantar pressure ratio length will be measured with the STATIPRO® static posturography platform.

Day 0
Plantar pressure ratio length.
기간: Month 6

Plantar pressure ratio length will be measured with the STATIPRO® static posturography platform.

Month 6
Plantar pressure ratio length.
기간: Year 1

Plantar pressure ratio length will be measured with the STATIPRO® static posturography platform.

Year 1
Plantar pressure ratio length.
기간: Year 2

Plantar pressure ratio length will be measured with the STATIPRO® static posturography platform.

Year 2
Plantar pressure ratio length.
기간: Year 5

Plantar pressure ratio length will be measured with the STATIPRO® static posturography platform.

Year 5
Walking velocity (cm/s).
기간: Day 0

Walking velocity will be measured with the GAITRite® Electronic Walkway.

Day 0
Walking velocity (cm/s).
기간: Month 6

Walking velocity will be measured with the GAITRite® Electronic Walkway.

Month 6
Walking velocity (cm/s).
기간: Year 1

Walking velocity will be measured with the GAITRite® Electronic Walkway.

Year 1
Walking velocity (cm/s).
기간: Year 2

Walking velocity will be measured with the GAITRite® Electronic Walkway.

Year 2
Walking velocity (cm/s).
기간: Year 5

Walking velocity will be measured with the GAITRite® Electronic Walkway.

Year 5
Cadence (steps/min).
기간: Day 0

: Cadence will be measured with the GAITRite® Electronic Walkway.

Day 0
Cadence (steps/min).
기간: Month 6

: Cadence will be measured with the GAITRite® Electronic Walkway.

Month 6
Cadence (steps/min).
기간: Year 1

: Cadence will be measured with the GAITRite® Electronic Walkway.

Year 1
Cadence (steps/min).
기간: Year 2

: Cadence will be measured with the GAITRite® Electronic Walkway.

Year 2
Cadence (steps/min).
기간: Year 5

: Cadence will be measured with the GAITRite® Electronic Walkway.

Year 5
Step length (left and right foot) (cm)
기간: DAy 0

Step length will be measured with the GAITRite® Electronic Walkway.

DAy 0
Step length (left and right foot) (cm)
기간: Month 6

Step length will be measured with the GAITRite® Electronic Walkway.

Month 6
Step length (left and right foot) (cm)
기간: Year 1

Step length will be measured with the GAITRite® Electronic Walkway.

Year 1
Step length (left and right foot) (cm)
기간: Year 2

Step length will be measured with the GAITRite® Electronic Walkway.

Year 2
Step length (left and right foot) (cm)
기간: Year 5

Step length will be measured with the GAITRite® Electronic Walkway.

Year 5
Stride length (cm).
기간: Day 0

Stride length will be measured with the GAITRite® Electronic Walkway.

Day 0
Stride length (cm).
기간: month 6

Stride length will be measured with the GAITRite® Electronic Walkway.

month 6
Stride length (cm).
기간: year 1

Stride length will be measured with the GAITRite® Electronic Walkway.

year 1
Stride length (cm).
기간: year 2

Stride length will be measured with the GAITRite® Electronic Walkway.

year 2
Stride length (cm).
기간: year 5

Stride length will be measured with the GAITRite® Electronic Walkway.

year 5
Single support time left and right foot (s).
기간: Day 0

Single support time will be measured with the GAITRite® Electronic Walkway.

Day 0
Single support time left and right foot (s).
기간: Month 6

Single support time will be measured with the GAITRite® Electronic Walkway.

Month 6
Single support time left and right foot (s).
기간: Year 1

Single support time will be measured with the GAITRite® Electronic Walkway.

Year 1
Single support time left and right foot (s).
기간: Year 2

Single support time will be measured with the GAITRite® Electronic Walkway.

Year 2
Single support time left and right foot (s).
기간: Year 5

Single support time will be measured with the GAITRite® Electronic Walkway.

Year 5
Double support time (s).
기간: Day 0

: Double support time will be measured with the GAITRite® Electronic Walkway.

Day 0
Double support time (s).
기간: Month 6

: Double support time will be measured with the GAITRite® Electronic Walkway.

Month 6
Double support time (s).
기간: YEar 1

: Double support time will be measured with the GAITRite® Electronic Walkway.

YEar 1
Double support time (s).
기간: Year 2

: Double support time will be measured with the GAITRite® Electronic Walkway.

Year 2
Double support time (s).
기간: Year 5

: Double support time will be measured with the GAITRite® Electronic Walkway.

Year 5
Swing time (s).
기간: Day 0

: Swing time will be measured with the GAITRite® Electronic Walkway.

Day 0
Swing time (s).
기간: Month 6

: Swing time will be measured with the GAITRite® Electronic Walkway.

Month 6
Swing time (s).
기간: Year 1

: Swing time will be measured with the GAITRite® Electronic Walkway.

Year 1
Swing time (s).
기간: Year 2

: Swing time will be measured with the GAITRite® Electronic Walkway.

Year 2
Swing time (s).
기간: Year 5

: Swing time will be measured with the GAITRite® Electronic Walkway.

Year 5
Swing phase (as a % of walking cycle).
기간: DAy 0

: Swing phase will be measured with the GAITRite® Electronic Walkway.

DAy 0
Swing phase (as a % of walking cycle).
기간: Month 6

: Swing phase will be measured with the GAITRite® Electronic Walkway.

Month 6
Swing phase (as a % of walking cycle).
기간: Year 1

: Swing phase will be measured with the GAITRite® Electronic Walkway.

Year 1
Swing phase (as a % of walking cycle).
기간: Year 2

: Swing phase will be measured with the GAITRite® Electronic Walkway.

Year 2
Swing phase (as a % of walking cycle).
기간: Year 5

: Swing phase will be measured with the GAITRite® Electronic Walkway.

Year 5
Stance phase (as a % of walking cycle).
기간: Day 0

Stance phase will be measured with the GAITRite® Electronic Walkway.

Day 0
Stance phase (as a % of walking cycle).
기간: Month 6

Stance phase will be measured with the GAITRite® Electronic Walkway.

Month 6
Stance phase (as a % of walking cycle).
기간: Year 1

Stance phase will be measured with the GAITRite® Electronic Walkway.

Year 1
Stance phase (as a % of walking cycle).
기간: Year 2

Stance phase will be measured with the GAITRite® Electronic Walkway.

Year 2
Stance phase (as a % of walking cycle).
기간: Year 5

Stance phase will be measured with the GAITRite® Electronic Walkway.

Year 5
Vo2max (maximal oxygen consumption) (mL/Kg/min).
기간: Day 0

: Vo2max will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Day 0
Vo2max (maximal oxygen consumption) (mL/Kg/min).
기간: Month 6

: Vo2max will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Month 6
Vo2max (maximal oxygen consumption) (mL/Kg/min).
기간: Year 1

: Vo2max will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 1
Vo2max (maximal oxygen consumption) (mL/Kg/min).
기간: Year 2

: Vo2max will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 2
Vo2max (maximal oxygen consumption) (mL/Kg/min).
기간: Year 5

: Vo2max will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 5
Maximum heart rate (bpm).
기간: Day 0

Maximum heart rate will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Day 0
Maximum heart rate (bpm).
기간: Month 6

Maximum heart rate will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Month 6
Maximum heart rate (bpm).
기간: Year 1

Maximum heart rate will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 1
Maximum heart rate (bpm).
기간: Year 2

Maximum heart rate will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 2
Maximum heart rate (bpm).
기간: Year 5

Maximum heart rate will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 5
Maximum power (Watts).
기간: Day 0

Maximum power will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Day 0
Maximum power (Watts).
기간: Month 6

Maximum power will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Month 6
Maximum power (Watts).
기간: Year 1

Maximum power will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 1
Maximum power (Watts).
기간: Year 2

Maximum power will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 2
Maximum power (Watts).
기간: Year 5

Maximum power will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 5
Threshold power (Watts).
기간: Day 0

Threshold power will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Day 0
Threshold power (Watts).
기간: Month 6

Threshold power will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Month 6
Threshold power (Watts).
기간: Year 1

Threshold power will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 1
Threshold power (Watts).
기간: Year 2

Threshold power will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 2
Threshold power (Watts).
기간: Year 5

Threshold power will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 5
Threshold heart rate (bpm).
기간: DAy 0

Threshold heart will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

DAy 0
Threshold heart rate (bpm).
기간: Month 6

Threshold heart will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Month 6
Threshold heart rate (bpm).
기간: Year 1

Threshold heart will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 1
Threshold heart rate (bpm).
기간: Year 2

Threshold heart will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 2
Threshold heart rate (bpm).
기간: Year 5

Threshold heart will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 5
Forced vital Capacity (L).
기간: Day 0

: Forced vital Capacity will be measured with a spirometry test.

Day 0
Forced vital Capacity (L).
기간: Month 6

: Forced vital Capacity will be measured with a spirometry test.

Month 6
Forced vital Capacity (L).
기간: Year 1

: Forced vital Capacity will be measured with a spirometry test.

Year 1
Forced vital Capacity (L).
기간: Year 2

: Forced vital Capacity will be measured with a spirometry test.

Year 2
Forced vital Capacity (L).
기간: Year 5

: Forced vital Capacity will be measured with a spirometry test.

Year 5
Forced Expiratory volume (L)
기간: Day 0

Forced Expiratory volume will be measured with a spirometry test.

Day 0
Forced Expiratory volume (L)
기간: Month 6

Forced Expiratory volume will be measured with a spirometry test.

Month 6
Forced Expiratory volume (L)
기간: Year 1

Forced Expiratory volume will be measured with a spirometry test.

Year 1
Forced Expiratory volume (L)
기간: Year 2

Forced Expiratory volume will be measured with a spirometry test.

Year 2
Forced Expiratory volume (L)
기간: Year 5

Forced Expiratory volume will be measured with a spirometry test.

Year 5
Tiffeneau ratio (%).
기간: Day 0

Tiffeneau ratio will be calculated by dividing the Forced Expiratory volume to the Forced vital Capacity.

Day 0
Tiffeneau ratio (%).
기간: Month 6

Tiffeneau ratio will be calculated by dividing the Forced Expiratory volume to the Forced vital Capacity.

Month 6
Tiffeneau ratio (%).
기간: Year 1

Tiffeneau ratio will be calculated by dividing the Forced Expiratory volume to the Forced vital Capacity.

Year 1
Tiffeneau ratio (%).
기간: Year 2

Tiffeneau ratio will be calculated by dividing the Forced Expiratory volume to the Forced vital Capacity.

Year 2
Tiffeneau ratio (%).
기간: Year 5

Tiffeneau ratio will be calculated by dividing the Forced Expiratory volume to the Forced vital Capacity.

Year 5
Ventilatory reserve (%).
기간: Day 0

Ventilatory reserve will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Day 0
Ventilatory reserve (%).
기간: Month 6

Ventilatory reserve will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Month 6
Ventilatory reserve (%).
기간: Year 1

Ventilatory reserve will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 1
Ventilatory reserve (%).
기간: Year 2

Ventilatory reserve will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 2
Ventilatory reserve (%).
기간: Year 5

Ventilatory reserve will be obtained by performing a cardiopulmonary exercise testing at maximal effort during incremental exercise on a cycle ergometer.

Year 5
Physical activity
기간: Day 0

Physical activity will be measured using the Global Physical Activity Questionnaire (GPAQ)

Day 0
Physical activity
기간: Month 6

Physical activity will be measured using the Global Physical Activity Questionnaire (GPAQ)

Month 6
Physical activity
기간: Year 1

Physical activity will be measured using the Global Physical Activity Questionnaire (GPAQ)

Year 1
Physical activity
기간: Year 2

Physical activity will be measured using the Global Physical Activity Questionnaire (GPAQ)

Year 2
Physical activity
기간: Year 5

Physical activity will be measured using the Global Physical Activity Questionnaire (GPAQ)

Year 5
Functional capacity timed-up and go
기간: Day 0

Functional capacity will be evaluated using the Timed-Up and Go test.

Day 0
Functional capacity timed-up and go
기간: Month 6

Functional capacity will be evaluated using the Timed-Up and Go test.

Month 6
Functional capacity timed-up and go
기간: Year 1

Functional capacity will be evaluated using the Timed-Up and Go test.

Year 1
Functional capacity timed-up and go
기간: Year 2

Functional capacity will be evaluated using the Timed-Up and Go test.

Year 2
Functional capacity timed-up and go
기간: Year 5

Functional capacity will be evaluated using the Timed-Up and Go test.

Year 5
Functional capacity TDM6
기간: Day 0

Functional capacity will be evaluated using the 6-minute walk test.

Day 0
Functional capacity TDM6
기간: Month 6

Functional capacity will be evaluated using the 6-minute walk test.

Month 6
Functional capacity TDM6
기간: Year 1

Functional capacity will be evaluated using the 6-minute walk test.

Year 1
Functional capacity TDM6
기간: Year 2

Functional capacity will be evaluated using the 6-minute walk test.

Year 2
Functional capacity TDM6
기간: Year 5

Functional capacity will be evaluated using the 6-minute walk test.

Year 5
Functional capacity Five Times Sit to Stand test.
기간: Day 0

Functional capacity will be evaluated using the Five Times Sit to Stand test.

Day 0
Functional capacity Five Times Sit to Stand test.
기간: Month 6

Functional capacity will be evaluated using the Five Times Sit to Stand test.

Month 6
Functional capacity Five Times Sit to Stand test.
기간: Year 1

Functional capacity will be evaluated using the Five Times Sit to Stand test.

Year 1
Functional capacity Five Times Sit to Stand test.
기간: Year 2

Functional capacity will be evaluated using the Five Times Sit to Stand test.

Year 2
Functional capacity Five Times Sit to Stand test.
기간: Year 5

Functional capacity will be evaluated using the Five Times Sit to Stand test.

Year 5
Functional capacity SPPB
기간: Day 0

Functional capacity will be evaluated using the Five Times Sit to Stand test.Functional capacity will be evaluated using the Short Physical Performance Battery test.

Day 0
Functional capacity SPPB
기간: Month 6

Functional capacity will be evaluated using the Five Times Sit to Stand test.Functional capacity will be evaluated using the Short Physical Performance Battery test.

Month 6
Functional capacity SPPB
기간: Year 1

Functional capacity will be evaluated using the Five Times Sit to Stand test.Functional capacity will be evaluated using the Short Physical Performance Battery test.

Year 1
Functional capacity SPPB
기간: Year 2

Functional capacity will be evaluated using the Five Times Sit to Stand test.Functional capacity will be evaluated using the Short Physical Performance Battery test.

Year 2
Functional capacity SPPB
기간: Year 5

Functional capacity will be evaluated using the Five Times Sit to Stand test.Functional capacity will be evaluated using the Short Physical Performance Battery test.

Year 5
Functional capacity the mini-BESTest.
기간: Day 0

Functional capacity will be evaluated using the mini-BESTest.

Day 0
Functional capacity the mini-BESTest.
기간: Month 6

Functional capacity will be evaluated using the mini-BESTest.

Month 6
Functional capacity the mini-BESTest.
기간: Year 1

Functional capacity will be evaluated using the mini-BESTest.

Year 1
Functional capacity the mini-BESTest.
기간: Year 2

Functional capacity will be evaluated using the mini-BESTest.

Year 2
Functional capacity the mini-BESTest.
기간: Year 5

Functional capacity will be evaluated using the mini-BESTest.

Year 5
Functional capacity Berg Balance Scale.
기간: Day 0

Functional capacity will be evaluated using the Berg Balance Scale.

Day 0
Functional capacity Berg Balance Scale.
기간: Month 6

Functional capacity will be evaluated using the Berg Balance Scale.

Month 6
Functional capacity Berg Balance Scale.
기간: Year 1

Functional capacity will be evaluated using the Berg Balance Scale.

Year 1
Functional capacity Berg Balance Scale.
기간: Year 2

Functional capacity will be evaluated using the Berg Balance Scale.

Year 2
Functional capacity Berg Balance Scale.
기간: Year 5

Functional capacity will be evaluated using the Berg Balance Scale.

Year 5
Functional capacity 10-meter walk test
기간: Day 0

Functional capacity will be evaluated using the 10-meter walk test (at usual and maximal pace).

Day 0
Functional capacity 10-meter walk test
기간: Month 6

Functional capacity will be evaluated using the 10-meter walk test (at usual and maximal pace).

Month 6
Functional capacity 10-meter walk test
기간: Year 1

Functional capacity will be evaluated using the 10-meter walk test (at usual and maximal pace).

Year 1
Functional capacity 10-meter walk test
기간: Year 2

Functional capacity will be evaluated using the 10-meter walk test (at usual and maximal pace).

Year 2
Functional capacity 10-meter walk test
기간: Year 5

Functional capacity will be evaluated using the 10-meter walk test (at usual and maximal pace).

Year 5
Dyspnea
기간: Day 0

Dyspnea will be evaluated by a Numeric Rating scale ranging from 0 to 10.

Day 0
Dyspnea
기간: Month 6

Dyspnea will be evaluated by a Numeric Rating scale ranging from 0 to 10.

Month 6
Dyspnea
기간: Year 1

Dyspnea will be evaluated by a Numeric Rating scale ranging from 0 to 10.

Year 1
Dyspnea
기간: Year 2

Dyspnea will be evaluated by a Numeric Rating scale ranging from 0 to 10.

Year 2
Dyspnea
기간: Year 5

Dyspnea will be evaluated by a Numeric Rating scale ranging from 0 to 10.

Year 5
Perceived exertion before, during and after effort
기간: DAy 0

Perceived exertion will be evaluated by a Numeric Rating scale ranging from 0 to 10.

DAy 0
Perceived exertion before, during and after effort
기간: Month 6

Perceived exertion will be evaluated by a Numeric Rating scale ranging from 0 to 10.

Month 6
Perceived exertion before, during and after effort
기간: Year 1

Perceived exertion will be evaluated by a Numeric Rating scale ranging from 0 to 10.

Year 1
Perceived exertion before, during and after effort
기간: Year 2

Perceived exertion will be evaluated by a Numeric Rating scale ranging from 0 to 10.

Year 2
Perceived exertion before, during and after effort
기간: Year 5

Perceived exertion will be evaluated by a Numeric Rating scale ranging from 0 to 10.

Year 5
Musculoskeletal Pain
기간: Day 0

: Pain will be measured by a visual analogue scale (VAS) ranging from 0 to 10 and possibly as appropriate by other questionnaires or specific scales.

Day 0
Musculoskeletal Pain
기간: Month 6

: Pain will be measured by a visual analogue scale (VAS) ranging from 0 to 10 and possibly as appropriate by other questionnaires or specific scales.

Month 6
Musculoskeletal Pain
기간: Year 1

: Pain will be measured by a visual analogue scale (VAS) ranging from 0 to 10 and possibly as appropriate by other questionnaires or specific scales.

Year 1
Musculoskeletal Pain
기간: Year 2

: Pain will be measured by a visual analogue scale (VAS) ranging from 0 to 10 and possibly as appropriate by other questionnaires or specific scales.

Year 2
Musculoskeletal Pain
기간: Year 5

: Pain will be measured by a visual analogue scale (VAS) ranging from 0 to 10 and possibly as appropriate by other questionnaires or specific scales.

Year 5
Sarcopenia risk
기간: Day 0

Sarcopenia risk will be evaluated with the SARC-F Questionnaire.

Day 0
Sarcopenia risk
기간: Month 6

Sarcopenia risk will be evaluated with the SARC-F Questionnaire.

Month 6
Sarcopenia risk
기간: Year 1

Sarcopenia risk will be evaluated with the SARC-F Questionnaire.

Year 1
Sarcopenia risk
기간: Year 2

Sarcopenia risk will be evaluated with the SARC-F Questionnaire.

Year 2
Sarcopenia risk
기간: Year 5

Sarcopenia risk will be evaluated with the SARC-F Questionnaire.

Year 5
Social insecurity
기간: Day 0

Social insecurity will be evaluated with the EPICES Score Questionnaire.

Day 0
Social insecurity
기간: Month 6

Social insecurity will be evaluated with the EPICES Score Questionnaire.

Month 6
Social insecurity
기간: Year 1

Social insecurity will be evaluated with the EPICES Score Questionnaire.

Year 1
Social insecurity
기간: Year 2

Social insecurity will be evaluated with the EPICES Score Questionnaire.

Year 2
Social insecurity
기간: Year 5

Social insecurity will be evaluated with the EPICES Score Questionnaire.

Year 5
Kinesiophobia
기간: Day 0

Kinesiophobia will be evaluated with the TAMPA Scale.

Day 0
Kinesiophobia
기간: Month 6

Kinesiophobia will be evaluated with the TAMPA Scale.

Month 6
Kinesiophobia
기간: Year 1

Kinesiophobia will be evaluated with the TAMPA Scale.

Year 1
Kinesiophobia
기간: Year 2

Kinesiophobia will be evaluated with the TAMPA Scale.

Year 2
Kinesiophobia
기간: Year 5

Kinesiophobia will be evaluated with the TAMPA Scale.

Year 5
Quality of life
기간: Day 0

Quality of life will be evaluated with the 36-Item Short Form Survey.

Day 0
Quality of life
기간: Month 6

Quality of life will be evaluated with the 36-Item Short Form Survey.

Month 6
Quality of life
기간: Year 1

Quality of life will be evaluated with the 36-Item Short Form Survey.

Year 1
Quality of life
기간: Year 2

Quality of life will be evaluated with the 36-Item Short Form Survey.

Year 2
Quality of life
기간: Year 5

Quality of life will be evaluated with the 36-Item Short Form Survey.

Year 5
: Balance confidence in performing various activities
기간: Day 0

Self-report balance confidence will be evaluated with the Activities-specific Balance Confidence (ABC) Scale.vey.

Day 0
: Balance confidence in performing various activities
기간: Month 6

Self-report balance confidence will be evaluated with the Activities-specific Balance Confidence (ABC) Scale.vey.

Month 6
: Balance confidence in performing various activities
기간: Year 1

Self-report balance confidence will be evaluated with the Activities-specific Balance Confidence (ABC) Scale.vey.

Year 1
: Balance confidence in performing various activities
기간: Year 2

Self-report balance confidence will be evaluated with the Activities-specific Balance Confidence (ABC) Scale.vey.

Year 2
: Balance confidence in performing various activities
기간: Year 5

Self-report balance confidence will be evaluated with the Activities-specific Balance Confidence (ABC) Scale.vey.

Year 5
Functioning in regards to activities of daily living.
기간: Day 0

Functioning will be evaluated with the Lawton Instrumental Activities of Daily Living (IADL) Scale.

Day 0
Functioning in regards to activities of daily living.
기간: Month 6

Functioning will be evaluated with the Lawton Instrumental Activities of Daily Living (IADL) Scale.

Month 6
Functioning in regards to activities of daily living.
기간: Year 1

Functioning will be evaluated with the Lawton Instrumental Activities of Daily Living (IADL) Scale.

Year 1
Functioning in regards to activities of daily living.
기간: Year 2

Functioning will be evaluated with the Lawton Instrumental Activities of Daily Living (IADL) Scale.

Year 2
Functioning in regards to activities of daily living.
기간: Year 5

Functioning will be evaluated with the Lawton Instrumental Activities of Daily Living (IADL) Scale.

Year 5
Exhaustion
기간: Day 0

Exhaustion will be evaluated with the FACIT-F Questionnaire.

Day 0
Exhaustion
기간: Month 6

Exhaustion will be evaluated with the FACIT-F Questionnaire.

Month 6
Exhaustion
기간: Year 1

Exhaustion will be evaluated with the FACIT-F Questionnaire.

Year 1
Exhaustion
기간: Year 2

Exhaustion will be evaluated with the FACIT-F Questionnaire.

Year 2
Exhaustion
기간: Year 5

Exhaustion will be evaluated with the FACIT-F Questionnaire.

Year 5
Patient's opinion about their knee and associated problems
기간: Day 0

: Outcomes will be evaluated with the Knee Injury and Osteoarthritis Outcome Score (KOOS).

Day 0
Patient's opinion about their knee and associated problems
기간: Month 6

: Outcomes will be evaluated with the Knee Injury and Osteoarthritis Outcome Score (KOOS).

Month 6
Patient's opinion about their knee and associated problems
기간: Year 1

: Outcomes will be evaluated with the Knee Injury and Osteoarthritis Outcome Score (KOOS).

Year 1
Patient's opinion about their knee and associated problems
기간: Year 2

: Outcomes will be evaluated with the Knee Injury and Osteoarthritis Outcome Score (KOOS).

Year 2
Patient's opinion about their knee and associated problems
기간: Year 5

: Outcomes will be evaluated with the Knee Injury and Osteoarthritis Outcome Score (KOOS).

Year 5
Patient's opinion about their hip and associated problems
기간: Day 0

Outcomes will be evaluated with the Hip Injury and Osteoarthritis Outcome Score (HOOS).

Day 0
Patient's opinion about their hip and associated problems
기간: Month 6

Outcomes will be evaluated with the Hip Injury and Osteoarthritis Outcome Score (HOOS).

Month 6
Patient's opinion about their hip and associated problems
기간: Year 1

Outcomes will be evaluated with the Hip Injury and Osteoarthritis Outcome Score (HOOS).

Year 1
Patient's opinion about their hip and associated problems
기간: Year 2

Outcomes will be evaluated with the Hip Injury and Osteoarthritis Outcome Score (HOOS).

Year 2
Patient's opinion about their hip and associated problems
기간: Year 5

Outcomes will be evaluated with the Hip Injury and Osteoarthritis Outcome Score (HOOS).

Year 5
Predicting discharge destination after total joint arthroplasty.
기간: Day 0

: Discharge destination will be evaluated with the Risk Assessment and Prediction Tool (RAPT);

Day 0
Predicting discharge destination after total joint arthroplasty.
기간: Month 6

: Discharge destination will be evaluated with the Risk Assessment and Prediction Tool (RAPT);

Month 6
Physical function in myositis patients
기간: Day 0

Physical function will be evaluated with the Stanford Health Assessment Questionnaire.

Day 0
Physical function in myositis patients
기간: Month 6

Physical function will be evaluated with the Stanford Health Assessment Questionnaire.

Month 6
Physical function in myositis patients
기간: Year 1

Physical function will be evaluated with the Stanford Health Assessment Questionnaire.

Year 1
Physical function in myositis patients
기간: Year 2

Physical function will be evaluated with the Stanford Health Assessment Questionnaire.

Year 2
Physical function in myositis patients
기간: Year 5

Physical function will be evaluated with the Stanford Health Assessment Questionnaire.

Year 5
Quality of life in Parkinson's Disease
기간: Day 0

Quality of life will be measured with the Parkinson's Disease Questionnaire-39 (PDQ-39).

Day 0
Quality of life in Parkinson's Disease
기간: Month 6

Quality of life will be measured with the Parkinson's Disease Questionnaire-39 (PDQ-39).

Month 6
Quality of life in Parkinson's Disease
기간: Year 1

Quality of life will be measured with the Parkinson's Disease Questionnaire-39 (PDQ-39).

Year 1
Quality of life in Parkinson's Disease
기간: Year 2

Quality of life will be measured with the Parkinson's Disease Questionnaire-39 (PDQ-39).

Year 2
Quality of life in Parkinson's Disease
기간: Year 5

Quality of life will be measured with the Parkinson's Disease Questionnaire-39 (PDQ-39).

Year 5
Actimetry.
기간: during 5 consecutive days after day 0

Actimetry data (energy expenditure, number of steps, sedentary time, total physical activity, etc.) will be obtained with the WGT3X-BT Actigraph inertial sensor unit.

during 5 consecutive days after day 0
Title: Muscle Cross-Sectional Area (CSA) of the quadriceps muscles (cm^2)
기간: Day 0

Cross-sectional area of the quadriceps muscles will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Day 0
Title: Muscle Cross-Sectional Area (CSA) of the quadriceps muscles (cm^2)
기간: Month 6

Cross-sectional area of the quadriceps muscles will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Month 6
Title: Muscle Cross-Sectional Area (CSA) of the quadriceps muscles (cm^2)
기간: Year 1

Cross-sectional area of the quadriceps muscles will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 1
Title: Muscle Cross-Sectional Area (CSA) of the quadriceps muscles (cm^2)
기간: Year 2

Cross-sectional area of the quadriceps muscles will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 2
Title: Muscle Cross-Sectional Area (CSA) of the quadriceps muscles (cm^2)
기간: Year 5

Cross-sectional area of the quadriceps muscles will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 5
Subcutaneous Adipose Tissue Thickness Over the Quadriceps (mm)
기간: Day 0

Thickness of the subcutaneous adipose tissue overlying the quadriceps muscles will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Day 0
Subcutaneous Adipose Tissue Thickness Over the Quadriceps (mm)
기간: Month 6

Thickness of the subcutaneous adipose tissue overlying the quadriceps muscles will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Month 6
Subcutaneous Adipose Tissue Thickness Over the Quadriceps (mm)
기간: Year 1

Thickness of the subcutaneous adipose tissue overlying the quadriceps muscles will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 1
Subcutaneous Adipose Tissue Thickness Over the Quadriceps (mm)
기간: Year 2

Thickness of the subcutaneous adipose tissue overlying the quadriceps muscles will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 2
Subcutaneous Adipose Tissue Thickness Over the Quadriceps (mm)
기간: Year 5

Thickness of the subcutaneous adipose tissue overlying the quadriceps muscles will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 5
Muscle Cross-Sectional Area (CSA) of the Medial Gastrocnemius (cm^2)
기간: Day 0

Cross-sectional area of the medial gastrocnemius muscle will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Day 0
Muscle Cross-Sectional Area (CSA) of the Medial Gastrocnemius (cm^2)
기간: Month 6

Cross-sectional area of the medial gastrocnemius muscle will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Month 6
Muscle Cross-Sectional Area (CSA) of the Medial Gastrocnemius (cm^2)
기간: Year 1

Cross-sectional area of the medial gastrocnemius muscle will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 1
Muscle Cross-Sectional Area (CSA) of the Medial Gastrocnemius (cm^2)
기간: Year 2

Cross-sectional area of the medial gastrocnemius muscle will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 2
Muscle Cross-Sectional Area (CSA) of the Medial Gastrocnemius (cm^2)
기간: Year 5

Cross-sectional area of the medial gastrocnemius muscle will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 5
Muscle Cross-Sectional Area (CSA) of the Lateral Gastrocnemius (cm^2)
기간: Day 0

Cross-sectional area of the lateral gastrocnemius muscle will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Day 0
Muscle Cross-Sectional Area (CSA) of the Lateral Gastrocnemius (cm^2)
기간: Month 6

Cross-sectional area of the lateral gastrocnemius muscle will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Month 6
Muscle Cross-Sectional Area (CSA) of the Lateral Gastrocnemius (cm^2)
기간: Year 1

Cross-sectional area of the lateral gastrocnemius muscle will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 1
Muscle Cross-Sectional Area (CSA) of the Lateral Gastrocnemius (cm^2)
기간: Year 2

Cross-sectional area of the lateral gastrocnemius muscle will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 2
Muscle Cross-Sectional Area (CSA) of the Lateral Gastrocnemius (cm^2)
기간: Year 5

Cross-sectional area of the lateral gastrocnemius muscle will be measured by conventional B-mode ultrasound using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 5
Quadriceps muscles Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Day 0

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Day 0
Quadriceps muscles Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Month 6

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Month 6
Quadriceps muscles Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Year 1

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 1
Quadriceps muscles Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Year 2

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 2
Quadriceps muscles Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Year 5

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 5
Medial Gastrocnemius Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Day 0

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Day 0
Medial Gastrocnemius Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Month 6

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Month 6
Medial Gastrocnemius Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Year 1

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 1
Medial Gastrocnemius Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Year 2

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 2
Medial Gastrocnemius Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Year 5

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 5
Lateral Gastrocnemius Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Day 0

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Day 0
Lateral Gastrocnemius Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Month 6

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Month 6
Lateral Gastrocnemius Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Year 1

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 1
Lateral Gastrocnemius Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Year 2

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 2
Lateral Gastrocnemius Quality Assessed by Shear Wave Elastography (kPa or m/s)
기간: Year 5

Muscle stiffness, reflecting muscle quality, will be assessed by Shear Wave Elastography (SWE) using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 5
Quadriceps muscles Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Day 0

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Day 0
Quadriceps muscles Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Month 6

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Month 6
Quadriceps muscles Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Year 1

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 1
Quadriceps muscles Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Year 2

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 2
Quadriceps muscles Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Year 5

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 5
Medial Gastrocnemius Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Day 0

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Day 0
Medial Gastrocnemius Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Month 6

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Month 6
Medial Gastrocnemius Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Year 1

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 1
Medial Gastrocnemius Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Year 2

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 2
Medial Gastrocnemius Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Year 5

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 5
Lateral Gastrocnemius Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Day 0

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Day 0
Lateral Gastrocnemius Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Month 6

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Month 6
Lateral Gastrocnemius Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Year 1

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 1
Lateral Gastrocnemius Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Year 2

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 2
Lateral Gastrocnemius Microvascularization Assessed by Superb Microvascular Imaging (SMI) (%)
기간: Year 5

Muscle microvascularization will be assessed using Superb Microvascular Imaging (SMI), a Doppler-based technique that detects very low-velocity blood flow without contrast agent injection, using the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 5
Quadriceps muscles Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Day 0

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Day 0
Quadriceps muscles Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Month 6

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Month 6
Quadriceps muscles Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Year 1

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 1
Quadriceps muscles Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Year 2

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 2
Quadriceps muscles Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Year 5

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 5
Medial Gastrocnemius Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Day 0

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Day 0
Medial Gastrocnemius Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Month 6

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Month 6
Medial Gastrocnemius Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Year 1

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 1
Medial Gastrocnemius Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Year 2

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 2
Medial Gastrocnemius Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Year 5

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 5
Lateral Gastrocnemius Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Day 0

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Day 0
Lateral Gastrocnemius Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Month 6

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Month 6
Lateral Gastrocnemius Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Year 1

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 1
Lateral Gastrocnemius Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Year 2

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 2
Lateral Gastrocnemius Blood Flow Velocity Measured by Doppler Ultrasound (cm/s)
기간: Year 5

Muscle blood flow velocity will be measured using Doppler ultrasound with the Canon Aplio a ultrasound system (Model CUS-AA000, Canon Medical Systems Corporation).

Year 5

공동 작업자 및 조사자

여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.

수사관

  • 수석 연구원: Frédéric Costes, University Hospital, Clermont-Ferrand

연구 기록 날짜

이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.

연구 주요 날짜

연구 시작 (실제)

2020년 8월 27일

기본 완료 (추정된)

2035년 8월 26일

연구 완료 (추정된)

2035년 8월 26일

연구 등록 날짜

최초 제출

2020년 4월 27일

QC 기준을 충족하는 최초 제출

2020년 5월 4일

처음 게시됨 (실제)

2020년 5월 5일

연구 기록 업데이트

마지막 업데이트 게시됨 (실제)

2026년 11월 4일

QC 기준을 충족하는 마지막 업데이트 제출

2026년 11월 2일

마지막으로 확인됨

2026년 10월 1일

추가 정보

이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .

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