- ICH GCP
- 미국 임상 시험 레지스트리
- 임상시험 NCT07710859
Concentric vs Eccentric Exercise in Blood Flow Restriction Training
Comparison of the Effectiveness of Concentric and Eccentric Exercises in Blood Flow Restriction Training
This randomized controlled trial will investigate the effects of blood flow restriction (BFR) training combined with concentric or eccentric exercise on upper extremity reaction speed, muscle strength, and muscle oxygenation in healthy adults aged 18-35 years. A total of 34 participants will be randomly allocated to either a BFR combined with concentric exercise group (n=17) or a BFR combined with eccentric exercise group (n=17).
Before the intervention, maximal muscle strength will be determined using a one-repetition maximum (1RM) test for the dominant elbow flexor muscles. Upper extremity reaction speed will be assessed using the Nelson Hand Reaction Test. Biceps brachii muscle strength will be measured with a digital dynamometer, and muscle oxygenation will be evaluated using a near-infrared spectroscopy (NIRS) device. All outcome measures will be obtained 72 hours before the intervention and repeated 72 hours after completion of the training program by the same investigator.
The findings of this study will contribute to understanding whether concentric or eccentric exercise combined with BFR training provides greater improvements in upper extremity reaction speed, muscle strength, and muscle oxygenation in healthy individuals.
연구 개요
연구 유형
등록 (추정된)
단계
- 해당 없음
연락처 및 위치
연구 장소
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Karabük Province
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Karabük, Karabük Province, 터키 (Türkiye), 78050
- Karabuk university
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참여기준
자격 기준
공부할 수 있는 나이
- 성인
건강한 자원 봉사자를 받아들입니다
설명
Inclusion Criteria:
- Being between 18 and 35 years of age
- Physically inactive or minimally active individuals (International Physical Activity Questionnaire-Short Form. IPAQ-CF, <3000 MET-min/week)
Exclusion Criteria:
- Having a history of musculoskeletal surgery within the last 6 months
- Individuals with a history of orthopedic surgery within the last 6 months
- Having high systolic blood pressure (≥140 mmHg)
- Having a current history of cardiovascular disease
- Participants who did not volunteer to participate in the study and did not provide informed consent were excluded from the study.
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 다른
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
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활성 비교기: CONCENTRIC GROUP
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Participants assigned to this group will perform blood flow restriction (BFR) training combined with concentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Participants assigned to this group will perform blood flow restriction (BFR) training combined with eccentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
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활성 비교기: ECCENTRIC GROUP
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Participants assigned to this group will perform blood flow restriction (BFR) training combined with concentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Participants assigned to this group will perform blood flow restriction (BFR) training combined with eccentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Upper Extremity Reaction Time
기간: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Upper extremity reaction time will be assessed using the Nelson Hand Reaction Test.
Participants will complete five trials, the highest and lowest values will be discarded, and the mean of the remaining three trials will be used for analysis.
Reaction time will be calculated from the ruler drop distance using the standard equation.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Biceps Brachii Muscle Strength
기간: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Biceps brachii muscle strength will be measured using an ActivForce 2 digital dynamometer.
Three maximal isometric contractions will be performed with 30-second rest intervals, and the highest value will be used for analysis.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Hand Grip Strength
기간: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Hand grip strength will be measured using a hydraulic hand dynamometer.
Participants will perform three maximal contractions with 30-second rest intervals, and the highest value will be recorded for analysis.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Pinch Strength
기간: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Pinch strength will be assessed using a pinch dynamometer.
Three maximal trials will be performed with 30-second rest intervals, and the highest value will be used for analysis.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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One-Repetition Maximum
기간: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Maximum muscle strength of the elbow flexors will be estimated using the Epley equation based on the maximum number of repetitions completed with a fixed load (2 kg for females and 5 kg for males).
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Muscle Oxygen Saturation
기간: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Muscle oxygen saturation (SmO₂) of the biceps brachii will be measured using a MOXY near-infrared spectroscopy (NIRS) device.
Baseline SmO₂ will be recorded before the 1RM test, continuous SmO₂ values will be monitored throughout the test, and recovery values will be recorded for 2-3 minutes after the test.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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공동 작업자 및 조사자
간행물 및 유용한 링크
연구 기록 날짜
연구 주요 날짜
연구 시작 (추정된)
기본 완료 (추정된)
연구 완료 (추정된)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .
concentric group에 대한 임상 시험
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