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Concentric vs Eccentric Exercise in Blood Flow Restriction Training

14. juli 2026 oppdatert av: METEHAN YANA, Karabuk University

Comparison of the Effectiveness of Concentric and Eccentric Exercises in Blood Flow Restriction Training

This randomized controlled trial will investigate the effects of blood flow restriction (BFR) training combined with concentric or eccentric exercise on upper extremity reaction speed, muscle strength, and muscle oxygenation in healthy adults aged 18-35 years. A total of 34 participants will be randomly allocated to either a BFR combined with concentric exercise group (n=17) or a BFR combined with eccentric exercise group (n=17).

Before the intervention, maximal muscle strength will be determined using a one-repetition maximum (1RM) test for the dominant elbow flexor muscles. Upper extremity reaction speed will be assessed using the Nelson Hand Reaction Test. Biceps brachii muscle strength will be measured with a digital dynamometer, and muscle oxygenation will be evaluated using a near-infrared spectroscopy (NIRS) device. All outcome measures will be obtained 72 hours before the intervention and repeated 72 hours after completion of the training program by the same investigator.

The findings of this study will contribute to understanding whether concentric or eccentric exercise combined with BFR training provides greater improvements in upper extremity reaction speed, muscle strength, and muscle oxygenation in healthy individuals.

Studieoversikt

Status

Påmelding etter invitasjon

Forhold

Intervensjon / Behandling

Studietype

Intervensjonell

Registrering (Antatt)

34

Fase

  • Ikke aktuelt

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiesteder

  • Tyrkia (Türkiye)
    • Karabük Province
      • Karabük, Karabük Province, Tyrkia (Türkiye), 78050
        • Karabuk University

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

  • Voksen

Tar imot friske frivillige

Ja

Beskrivelse

Inclusion Criteria:

  • Being between 18 and 35 years of age
  • Physically inactive or minimally active individuals (International Physical Activity Questionnaire-Short Form. IPAQ-CF, <3000 MET-min/week)

Exclusion Criteria:

  • Having a history of musculoskeletal surgery within the last 6 months
  • Individuals with a history of orthopedic surgery within the last 6 months
  • Having high systolic blood pressure (≥140 mmHg)
  • Having a current history of cardiovascular disease
  • Participants who did not volunteer to participate in the study and did not provide informed consent were excluded from the study.

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

  • Primært formål: Annen
  • Tildeling: Randomisert
  • Intervensjonsmodell: Parallell tildeling
  • Masking: Ingen (Open Label)

Våpen og intervensjoner

Deltakergruppe / Arm
Intervensjon / Behandling
Aktiv komparator: CONCENTRIC GROUP
Annen: concentric group
Participants assigned to this group will perform blood flow restriction (BFR) training combined with concentric elbow flexion exercises using the dominant upper extremity. Training will be performed three times per week for four weeks (12 sessions). Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm. The cuff pressure will be set at 50% of the individual's arterial occlusion pressure. Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Annen: eccentric group
Participants assigned to this group will perform blood flow restriction (BFR) training combined with eccentric elbow flexion exercises using the dominant upper extremity. Training will be performed three times per week for four weeks (12 sessions). Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm. The cuff pressure will be set at 50% of the individual's arterial occlusion pressure. Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Aktiv komparator: ECCENTRIC GROUP
Annen: concentric group
Participants assigned to this group will perform blood flow restriction (BFR) training combined with concentric elbow flexion exercises using the dominant upper extremity. Training will be performed three times per week for four weeks (12 sessions). Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm. The cuff pressure will be set at 50% of the individual's arterial occlusion pressure. Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Annen: eccentric group
Participants assigned to this group will perform blood flow restriction (BFR) training combined with eccentric elbow flexion exercises using the dominant upper extremity. Training will be performed three times per week for four weeks (12 sessions). Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm. The cuff pressure will be set at 50% of the individual's arterial occlusion pressure. Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.

Hva måler studien?

Primære resultatmål

Resultatmål
Tiltaksbeskrivelse
Tidsramme
Upper Extremity Reaction Time
Tidsramme: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Upper extremity reaction time will be assessed using the Nelson Hand Reaction Test. Participants will complete five trials, the highest and lowest values will be discarded, and the mean of the remaining three trials will be used for analysis. Reaction time will be calculated from the ruler drop distance using the standard equation.
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Biceps Brachii Muscle Strength
Tidsramme: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Biceps brachii muscle strength will be measured using an ActivForce 2 digital dynamometer. Three maximal isometric contractions will be performed with 30-second rest intervals, and the highest value will be used for analysis.
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Hand Grip Strength
Tidsramme: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Hand grip strength will be measured using a hydraulic hand dynamometer. Participants will perform three maximal contractions with 30-second rest intervals, and the highest value will be recorded for analysis.
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Pinch Strength
Tidsramme: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Pinch strength will be assessed using a pinch dynamometer. Three maximal trials will be performed with 30-second rest intervals, and the highest value will be used for analysis.
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
One-Repetition Maximum
Tidsramme: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Maximum muscle strength of the elbow flexors will be estimated using the Epley equation based on the maximum number of repetitions completed with a fixed load (2 kg for females and 5 kg for males).
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Muscle Oxygen Saturation
Tidsramme: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Muscle oxygen saturation (SmO₂) of the biceps brachii will be measured using a MOXY near-infrared spectroscopy (NIRS) device. Baseline SmO₂ will be recorded before the 1RM test, continuous SmO₂ values will be monitored throughout the test, and recovery values will be recorded for 2-3 minutes after the test.
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.

Samarbeidspartnere og etterforskere

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Sponsor

Karabuk University

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Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart (Antatt)

1. august 2026

Primær fullføring (Antatt)

1. oktober 2026

Studiet fullført (Antatt)

1. november 2026

Datoer for studieregistrering

Først innsendt

14. juli 2026

Først innsendt som oppfylte QC-kriteriene

14. juli 2026

Først lagt ut (Faktiske)

17. juli 2026

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

17. juli 2026

Siste oppdatering sendt inn som oppfylte QC-kriteriene

14. juli 2026

Sist bekreftet

1. juli 2026

Mer informasjon

Begreper knyttet til denne studien

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

  • blood flow restriction

Plan for individuelle deltakerdata (IPD)

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NEI

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Nei

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Nei

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