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Concentric vs Eccentric Exercise in Blood Flow Restriction Training

14 juillet 2026 mis à jour par: METEHAN YANA, Karabuk University

Comparison of the Effectiveness of Concentric and Eccentric Exercises in Blood Flow Restriction Training

This randomized controlled trial will investigate the effects of blood flow restriction (BFR) training combined with concentric or eccentric exercise on upper extremity reaction speed, muscle strength, and muscle oxygenation in healthy adults aged 18-35 years. A total of 34 participants will be randomly allocated to either a BFR combined with concentric exercise group (n=17) or a BFR combined with eccentric exercise group (n=17).

Before the intervention, maximal muscle strength will be determined using a one-repetition maximum (1RM) test for the dominant elbow flexor muscles. Upper extremity reaction speed will be assessed using the Nelson Hand Reaction Test. Biceps brachii muscle strength will be measured with a digital dynamometer, and muscle oxygenation will be evaluated using a near-infrared spectroscopy (NIRS) device. All outcome measures will be obtained 72 hours before the intervention and repeated 72 hours after completion of the training program by the same investigator.

The findings of this study will contribute to understanding whether concentric or eccentric exercise combined with BFR training provides greater improvements in upper extremity reaction speed, muscle strength, and muscle oxygenation in healthy individuals.

Aperçu de l'étude

Statut

Inscription sur invitation

Les conditions

Intervention / Traitement

Type d'étude

Interventionnel

Inscription (Estimé)

34

Phase

  • N'est pas applicable

Contacts et emplacements

Cette section fournit les coordonnées de ceux qui mènent l'étude et des informations sur le lieu où cette étude est menée.

Lieux d'étude

  • Turquie (Türkiye)
    • Karabük Province
      • Karabük, Karabük Province, Turquie (Türkiye), 78050
        • Karabuk University

Critères de participation

Les chercheurs recherchent des personnes qui correspondent à une certaine description, appelée critères d'éligibilité. Certains exemples de ces critères sont l'état de santé général d'une personne ou des traitements antérieurs.

Critère d'éligibilité

Âges éligibles pour étudier

  • Adulte

Accepte les volontaires sains

Oui

La description

Inclusion Criteria:

  • Being between 18 and 35 years of age
  • Physically inactive or minimally active individuals (International Physical Activity Questionnaire-Short Form. IPAQ-CF, <3000 MET-min/week)

Exclusion Criteria:

  • Having a history of musculoskeletal surgery within the last 6 months
  • Individuals with a history of orthopedic surgery within the last 6 months
  • Having high systolic blood pressure (≥140 mmHg)
  • Having a current history of cardiovascular disease
  • Participants who did not volunteer to participate in the study and did not provide informed consent were excluded from the study.

Plan d'étude

Cette section fournit des détails sur le plan d'étude, y compris la façon dont l'étude est conçue et ce que l'étude mesure.

Comment l'étude est-elle conçue ?

Détails de conception

  • Objectif principal: Autre
  • Répartition: Randomisé
  • Modèle interventionnel: Affectation parallèle
  • Masquage: Aucun (étiquette ouverte)

Armes et Interventions

Groupe de participants / Bras
Intervention / Traitement
Comparateur actif: CONCENTRIC GROUP
Autre: concentric group
Participants assigned to this group will perform blood flow restriction (BFR) training combined with concentric elbow flexion exercises using the dominant upper extremity. Training will be performed three times per week for four weeks (12 sessions). Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm. The cuff pressure will be set at 50% of the individual's arterial occlusion pressure. Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Autre: eccentric group
Participants assigned to this group will perform blood flow restriction (BFR) training combined with eccentric elbow flexion exercises using the dominant upper extremity. Training will be performed three times per week for four weeks (12 sessions). Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm. The cuff pressure will be set at 50% of the individual's arterial occlusion pressure. Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Comparateur actif: ECCENTRIC GROUP
Autre: concentric group
Participants assigned to this group will perform blood flow restriction (BFR) training combined with concentric elbow flexion exercises using the dominant upper extremity. Training will be performed three times per week for four weeks (12 sessions). Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm. The cuff pressure will be set at 50% of the individual's arterial occlusion pressure. Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Autre: eccentric group
Participants assigned to this group will perform blood flow restriction (BFR) training combined with eccentric elbow flexion exercises using the dominant upper extremity. Training will be performed three times per week for four weeks (12 sessions). Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm. The cuff pressure will be set at 50% of the individual's arterial occlusion pressure. Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.

Que mesure l'étude ?

Principaux critères de jugement

Mesure des résultats
Description de la mesure
Délai
Upper Extremity Reaction Time
Délai: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Upper extremity reaction time will be assessed using the Nelson Hand Reaction Test. Participants will complete five trials, the highest and lowest values will be discarded, and the mean of the remaining three trials will be used for analysis. Reaction time will be calculated from the ruler drop distance using the standard equation.
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Biceps Brachii Muscle Strength
Délai: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Biceps brachii muscle strength will be measured using an ActivForce 2 digital dynamometer. Three maximal isometric contractions will be performed with 30-second rest intervals, and the highest value will be used for analysis.
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Hand Grip Strength
Délai: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Hand grip strength will be measured using a hydraulic hand dynamometer. Participants will perform three maximal contractions with 30-second rest intervals, and the highest value will be recorded for analysis.
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Pinch Strength
Délai: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Pinch strength will be assessed using a pinch dynamometer. Three maximal trials will be performed with 30-second rest intervals, and the highest value will be used for analysis.
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
One-Repetition Maximum
Délai: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Maximum muscle strength of the elbow flexors will be estimated using the Epley equation based on the maximum number of repetitions completed with a fixed load (2 kg for females and 5 kg for males).
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Muscle Oxygen Saturation
Délai: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Muscle oxygen saturation (SmO₂) of the biceps brachii will be measured using a MOXY near-infrared spectroscopy (NIRS) device. Baseline SmO₂ will be recorded before the 1RM test, continuous SmO₂ values will be monitored throughout the test, and recovery values will be recorded for 2-3 minutes after the test.
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.

Collaborateurs et enquêteurs

C'est ici que vous trouverez les personnes et les organisations impliquées dans cette étude.

Parrainer

Karabuk University

Publications et liens utiles

La personne responsable de la saisie des informations sur l'étude fournit volontairement ces publications. Il peut s'agir de tout ce qui concerne l'étude.

Publications générales

Dates d'enregistrement des études

Ces dates suivent la progression des dossiers d'étude et des soumissions de résultats sommaires à ClinicalTrials.gov. Les dossiers d'étude et les résultats rapportés sont examinés par la Bibliothèque nationale de médecine (NLM) pour s'assurer qu'ils répondent à des normes de contrôle de qualité spécifiques avant d'être publiés sur le site Web public.

Dates principales de l'étude

Début de l'étude (Estimé)

1 août 2026

Achèvement primaire (Estimé)

1 octobre 2026

Achèvement de l'étude (Estimé)

1 novembre 2026

Dates d'inscription aux études

Première soumission

14 juillet 2026

Première soumission répondant aux critères de contrôle qualité

14 juillet 2026

Première publication (Réel)

17 juillet 2026

Mises à jour des dossiers d'étude

Dernière mise à jour publiée (Réel)

17 juillet 2026

Dernière mise à jour soumise répondant aux critères de contrôle qualité

14 juillet 2026

Dernière vérification

1 juillet 2026

Plus d'information

Termes liés à cette étude

Termes MeSH pertinents supplémentaires

Autres numéros d'identification d'étude

  • blood flow restriction

Plan pour les données individuelles des participants (IPD)

Prévoyez-vous de partager les données individuelles des participants (DPI) ?

NON

Informations sur les médicaments et les dispositifs, documents d'étude

Étudie un produit pharmaceutique réglementé par la FDA américaine

Non

Étudie un produit d'appareil réglementé par la FDA américaine

Non

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