Concentric vs Eccentric Exercise in Blood Flow Restriction Training
2026年7月14日 更新者：METEHAN YANA、Karabuk University
Comparison of the Effectiveness of Concentric and Eccentric Exercises in Blood Flow Restriction Training
This randomized controlled trial will investigate the effects of blood flow restriction (BFR) training combined with concentric or eccentric exercise on upper extremity reaction speed, muscle strength, and muscle oxygenation in healthy adults aged 18-35 years. A total of 34 participants will be randomly allocated to either a BFR combined with concentric exercise group (n=17) or a BFR combined with eccentric exercise group (n=17).
Before the intervention, maximal muscle strength will be determined using a one-repetition maximum (1RM) test for the dominant elbow flexor muscles. Upper extremity reaction speed will be assessed using the Nelson Hand Reaction Test. Biceps brachii muscle strength will be measured with a digital dynamometer, and muscle oxygenation will be evaluated using a near-infrared spectroscopy (NIRS) device. All outcome measures will be obtained 72 hours before the intervention and repeated 72 hours after completion of the training program by the same investigator.
The findings of this study will contribute to understanding whether concentric or eccentric exercise combined with BFR training provides greater improvements in upper extremity reaction speed, muscle strength, and muscle oxygenation in healthy individuals.
研究概览
研究类型
介入性
注册 (估计的)
34
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
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Karabük Province
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Karabük、Karabük Province、土耳其（türkiye）、78050
- Karabuk University
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参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 成人
接受健康志愿者
是的
描述
Inclusion Criteria:
- Being between 18 and 35 years of age
- Physically inactive or minimally active individuals (International Physical Activity Questionnaire-Short Form. IPAQ-CF, <3000 MET-min/week)
Exclusion Criteria:
- Having a history of musculoskeletal surgery within the last 6 months
- Individuals with a history of orthopedic surgery within the last 6 months
- Having high systolic blood pressure (≥140 mmHg)
- Having a current history of cardiovascular disease
- Participants who did not volunteer to participate in the study and did not provide informed consent were excluded from the study.
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：其他
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
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有源比较器：CONCENTRIC GROUP
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Participants assigned to this group will perform blood flow restriction (BFR) training combined with concentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Participants assigned to this group will perform blood flow restriction (BFR) training combined with eccentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
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有源比较器：ECCENTRIC GROUP
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Participants assigned to this group will perform blood flow restriction (BFR) training combined with concentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Participants assigned to this group will perform blood flow restriction (BFR) training combined with eccentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Upper Extremity Reaction Time
大体时间：Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Upper extremity reaction time will be assessed using the Nelson Hand Reaction Test.
Participants will complete five trials, the highest and lowest values will be discarded, and the mean of the remaining three trials will be used for analysis.
Reaction time will be calculated from the ruler drop distance using the standard equation.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Biceps Brachii Muscle Strength
大体时间：Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Biceps brachii muscle strength will be measured using an ActivForce 2 digital dynamometer.
Three maximal isometric contractions will be performed with 30-second rest intervals, and the highest value will be used for analysis.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Hand Grip Strength
大体时间：Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Hand grip strength will be measured using a hydraulic hand dynamometer.
Participants will perform three maximal contractions with 30-second rest intervals, and the highest value will be recorded for analysis.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Pinch Strength
大体时间：Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Pinch strength will be assessed using a pinch dynamometer.
Three maximal trials will be performed with 30-second rest intervals, and the highest value will be used for analysis.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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One-Repetition Maximum
大体时间：Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Maximum muscle strength of the elbow flexors will be estimated using the Epley equation based on the maximum number of repetitions completed with a fixed load (2 kg for females and 5 kg for males).
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Muscle Oxygen Saturation
大体时间：Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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Muscle oxygen saturation (SmO₂) of the biceps brachii will be measured using a MOXY near-infrared spectroscopy (NIRS) device.
Baseline SmO₂ will be recorded before the 1RM test, continuous SmO₂ values will be monitored throughout the test, and recovery values will be recorded for 2-3 minutes after the test.
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Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (估计的)
2026年8月1日
初级完成 (估计的)
2026年10月1日
研究完成 (估计的)
2026年11月1日
研究注册日期
首次提交
2026年7月14日
首先提交符合 QC 标准的
2026年7月14日
首次发布 (实际的)
2026年7月17日
研究记录更新
最后更新发布 (实际的)
2026年7月17日
上次提交的符合 QC 标准的更新
2026年7月14日
最后验证
2026年7月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.