Concentric vs Eccentric Exercise in Blood Flow Restriction Training
14 juli 2026 uppdaterad av: METEHAN YANA, Karabuk University
Comparison of the Effectiveness of Concentric and Eccentric Exercises in Blood Flow Restriction Training
This randomized controlled trial will investigate the effects of blood flow restriction (BFR) training combined with concentric or eccentric exercise on upper extremity reaction speed, muscle strength, and muscle oxygenation in healthy adults aged 18-35 years. A total of 34 participants will be randomly allocated to either a BFR combined with concentric exercise group (n=17) or a BFR combined with eccentric exercise group (n=17).
Before the intervention, maximal muscle strength will be determined using a one-repetition maximum (1RM) test for the dominant elbow flexor muscles. Upper extremity reaction speed will be assessed using the Nelson Hand Reaction Test. Biceps brachii muscle strength will be measured with a digital dynamometer, and muscle oxygenation will be evaluated using a near-infrared spectroscopy (NIRS) device. All outcome measures will be obtained 72 hours before the intervention and repeated 72 hours after completion of the training program by the same investigator.
The findings of this study will contribute to understanding whether concentric or eccentric exercise combined with BFR training provides greater improvements in upper extremity reaction speed, muscle strength, and muscle oxygenation in healthy individuals.
Studieöversikt
Status
Anmälan via inbjudan
Betingelser
Intervention / Behandling
Studietyp
Interventionell
Inskrivning (Beräknad)
34
Fas
- Inte tillämpbar
Kontakter och platser
Det här avsnittet innehåller kontaktuppgifter för dem som genomför studien och information om var denna studie genomförs.
Studieorter
-
-
Karabük Province
-
Karabük, Karabük Province, Turkiet (Türkiye), 78050
- Karabuk University
-
-
Deltagandekriterier
Forskare letar efter personer som passar en viss beskrivning, så kallade behörighetskriterier. Några exempel på dessa kriterier är en persons allmänna hälsotillstånd eller tidigare behandlingar.
Urvalskriterier
Åldrar som är berättigade till studier
- Vuxen
Tar emot friska volontärer
Ja
Beskrivning
Inclusion Criteria:
- Being between 18 and 35 years of age
- Physically inactive or minimally active individuals (International Physical Activity Questionnaire-Short Form. IPAQ-CF, <3000 MET-min/week)
Exclusion Criteria:
- Having a history of musculoskeletal surgery within the last 6 months
- Individuals with a history of orthopedic surgery within the last 6 months
- Having high systolic blood pressure (≥140 mmHg)
- Having a current history of cardiovascular disease
- Participants who did not volunteer to participate in the study and did not provide informed consent were excluded from the study.
Studieplan
Det här avsnittet ger detaljer om studieplanen, inklusive hur studien är utformad och vad studien mäter.
Hur är studien utformad?
Designdetaljer
- Primärt syfte: Övrig
- Tilldelning: Randomiserad
- Interventionsmodell: Parallellt uppdrag
- Maskning: Ingen (Open Label)
Vapen och interventioner
Deltagargrupp / Arm |
Intervention / Behandling |
|---|---|
|
Aktiv komparator: CONCENTRIC GROUP
|
Participants assigned to this group will perform blood flow restriction (BFR) training combined with concentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Participants assigned to this group will perform blood flow restriction (BFR) training combined with eccentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
|
|
Aktiv komparator: ECCENTRIC GROUP
|
Participants assigned to this group will perform blood flow restriction (BFR) training combined with concentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Participants assigned to this group will perform blood flow restriction (BFR) training combined with eccentric elbow flexion exercises using the dominant upper extremity.
Training will be performed three times per week for four weeks (12 sessions).
Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm.
The cuff pressure will be set at 50% of the individual's arterial occlusion pressure.
Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
|
Vad mäter studien?
Primära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
|
Upper Extremity Reaction Time
Tidsram: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
|
Upper extremity reaction time will be assessed using the Nelson Hand Reaction Test.
Participants will complete five trials, the highest and lowest values will be discarded, and the mean of the remaining three trials will be used for analysis.
Reaction time will be calculated from the ruler drop distance using the standard equation.
|
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
|
|
Biceps Brachii Muscle Strength
Tidsram: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
|
Biceps brachii muscle strength will be measured using an ActivForce 2 digital dynamometer.
Three maximal isometric contractions will be performed with 30-second rest intervals, and the highest value will be used for analysis.
|
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
|
|
Hand Grip Strength
Tidsram: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
|
Hand grip strength will be measured using a hydraulic hand dynamometer.
Participants will perform three maximal contractions with 30-second rest intervals, and the highest value will be recorded for analysis.
|
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
|
|
Pinch Strength
Tidsram: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
|
Pinch strength will be assessed using a pinch dynamometer.
Three maximal trials will be performed with 30-second rest intervals, and the highest value will be used for analysis.
|
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
|
|
One-Repetition Maximum
Tidsram: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
|
Maximum muscle strength of the elbow flexors will be estimated using the Epley equation based on the maximum number of repetitions completed with a fixed load (2 kg for females and 5 kg for males).
|
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
|
|
Muscle Oxygen Saturation
Tidsram: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
|
Muscle oxygen saturation (SmO₂) of the biceps brachii will be measured using a MOXY near-infrared spectroscopy (NIRS) device.
Baseline SmO₂ will be recorded before the 1RM test, continuous SmO₂ values will be monitored throughout the test, and recovery values will be recorded for 2-3 minutes after the test.
|
Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
|
Samarbetspartners och utredare
Det är här du hittar personer och organisationer som är involverade i denna studie.
Sponsor
Publikationer och användbara länkar
Den som ansvarar för att lägga in information om studien tillhandahåller frivilligt dessa publikationer. Dessa kan handla om allt som har med studien att göra.
Studieavstämningsdatum
Dessa datum spårar framstegen för inlämningar av studieposter och sammanfattande resultat till ClinicalTrials.gov. Studieposter och rapporterade resultat granskas av National Library of Medicine (NLM) för att säkerställa att de uppfyller specifika kvalitetskontrollstandarder innan de publiceras på den offentliga webbplatsen.
Studera stora datum
Studiestart (Beräknad)
1 augusti 2026
Primärt slutförande (Beräknad)
1 oktober 2026
Avslutad studie (Beräknad)
1 november 2026
Studieregistreringsdatum
Först inskickad
14 juli 2026
Först inskickad som uppfyllde QC-kriterierna
14 juli 2026
Första postat (Faktisk)
17 juli 2026
Uppdateringar av studier
Senaste uppdatering publicerad (Faktisk)
17 juli 2026
Senaste inskickade uppdateringen som uppfyllde QC-kriterierna
14 juli 2026
Senast verifierad
1 juli 2026
Mer information
Termer relaterade till denna studie
Ytterligare relevanta MeSH-villkor
Andra studie-ID-nummer
- blood flow restriction
Plan för individuella deltagardata (IPD)
Planerar du att dela individuella deltagardata (IPD)?
NEJ
Läkemedels- och apparatinformation, studiedokument
Studerar en amerikansk FDA-reglerad läkemedelsprodukt
Nej
Studerar en amerikansk FDA-reglerad produktprodukt
Nej
Denna information hämtades direkt från webbplatsen clinicaltrials.gov utan några ändringar. Om du har några önskemål om att ändra, ta bort eller uppdatera dina studieuppgifter, vänligen kontakta register@clinicaltrials.gov. Så snart en ändring har implementerats på clinicaltrials.gov, kommer denna att uppdateras automatiskt även på vår webbplats .