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Multicentre Study to Record the Mental and Physical Effects of the COVID-19 Pandemic (COBESITY-Study)

28. mars 2022 oppdatert av: Universitätsklinikum Hamburg-Eppendorf

International, Prospective Multicentre Study to Record the Mental and Physical Effects of the COVID-19 Pandemic on Two Obese Patient Cohorts Pre- and Post-bariatric Surgery (COBESITY-Study)

Prospective, international multicenter study to investigate the physical and psychological effects of the COVID-19 pandemic in two obese patient cohorts (BMI ≥ 25 kg/m²) pre- and post-bariatric surgery. In addition, the investigation of country-specific differences will be performed.

Studieoversikt

Status

Rekruttering

Forhold

Detaljert beskrivelse

The COVID-19 pandemic, first reported in November 2019, has led to a global health systems emergency. The number of confirmed COVID-19-associated deaths, according to WHO, is higher in countries with high obesity prevalence. However, whether obesity is an independent risk factor of the severity of COVID-19 remains unclear.

Obesity represents one of the major health problems worldwide and the COVID-19 pandemic is expected to further increase obesity prevalence rates. Initial research indicates that the pandemic has also led to an increased incidence and/or worsening of depression and eating disorders. Additional weight gain due to the COVID-19 pandemic may be suspected to increase the prevalence of psychological comorbidities in patients before weight-reducing surgery compared to patients who have already undergone weight-reducing surgery.

Therefore, the main aim of this international study is to gain a better understanding of the mental and physical effects of the coronavirus pandemic on obese patients before and after a weight-reducing surgery and use this to develop approaches for solutions. This study also aims to investigate the country-specific differences (Germany vs England) as well as the differences in the mental effects experienced by overweight patients who have or have not been infected with COVID-19.

To achieve these aims, obese patients aged 18 years and older, before and after weight-reducing surgery, will be recruited from the bariatric surgery clinic at King's College Hospital, NHS Trust Foundation as well as from the Medical University Hospital Hamburg-Eppendorf, Germany. Participants will be asked to complete a questionnaire about their health, socio-economic status, and the effects of the COVID-19 pandemic on their physical and mental health. The questionnaire will take 15 minutes to complete and can be done at home or during the patient's appointment at the bariatric surgery clinic to minimise unnecessary travel.

Studietype

Observasjonsmessig

Registrering (Forventet)

500

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiekontakt

  • Navn: Pia Roser, MD
  • Telefonnummer: +494074100
  • E-post: p.roser@uke.de

Studiesteder

  • Tyskland
      • Hamburg, Tyskland
        • Rekruttering
        • Universitätsklinikum Hamburg-Eppendorf
        • Ta kontakt med:

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

18 år og eldre (Voksen, Eldre voksen)

Tar imot friske frivillige

Nei

Kjønn som er kvalifisert for studier

Alle

Prøvetakingsmetode

Ikke-sannsynlighetsprøve

Studiepopulasjon

Overweight and obese patients with or without bariatric surgery

Beskrivelse

Inclusion Criteria:

Overweight and obese patient cohort

  • Age: 18 years and older
  • BMI ≥ 25kg/m²

Overweight and obese patient cohort with bariatric surgery

  • Age: 18 years and older
  • BMI ≥ 25kg/m²
  • Status post sleeve or gastric bypass surgery

Exclusion Criteria:

  • Age under 18 years
  • Cognitive, mental and/or linguistic limitations to complete the questionnaire independently
  • Severe somatic illnesses, such as tumour diseases
  • Pregnancy or breastfeeding
  • Acute need for treatment due to comorbid mental disorders

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

Kohorter og intervensjoner

Gruppe / Kohort
Overweight and obese patient cohort
  • Age: 18 years and older
  • BMI ≥ 25kg/m²
Overweight and obese patient cohort with bariatric surgery
  • Age: 18 years and older
  • BMI ≥ 25kg/m²
  • Status post sleeve or gastric bypass surgery

Hva måler studien?

Primære resultatmål

Resultatmål
Tiltaksbeskrivelse
Tidsramme
PHQ-4
Tidsramme: Before the COVID-19 pandemic vs. since the COVID-19 pandemic
Impact of the COVID-19 pandemic on mental health (measured by PHQ-4, PSS-10, and EDEQ scores) as well as on physical health (measured by Δ BMI (kg/m^2) before and after the onset of the pandemic) in two obese patient cohorts pre- and post- bariatric surgery.
Before the COVID-19 pandemic vs. since the COVID-19 pandemic
PSS-10
Tidsramme: Before the COVID-19 pandemic vs. since the COVID-19 pandemic
Impact of the COVID-19 pandemic on mental health (measured by PHQ-4, PSS-10, and EDEQ scores) as well as on physical health (measured by Δ BMI (kg/m^2) before and after the onset of the pandemic) in two obese patient cohorts pre- and post- bariatric surgery.
Before the COVID-19 pandemic vs. since the COVID-19 pandemic
EDEQ-score
Tidsramme: Before the COVID-19 pandemic vs. since the COVID-19 pandemic
Impact of the COVID-19 pandemic on mental health (measured by PHQ-4, PSS-10, and EDEQ scores) as well as on physical health (measured by Δ BMI (kg/m^2) before and after the onset of the pandemic) in two obese patient cohorts pre- and post- bariatric surgery.
Before the COVID-19 pandemic vs. since the COVID-19 pandemic
BMI
Tidsramme: Before the COVID-19 pandemic vs. since the COVID-19 pandemic
Impact of the COVID-19 pandemic on mental health (measured by PHQ-4, PSS-10, and EDEQ scores) as well as on physical health (measured by Δ BMI (kg/m^2) before and after the onset of the pandemic) in two obese patient cohorts pre- and post- bariatric surgery.
Before the COVID-19 pandemic vs. since the COVID-19 pandemic

Sekundære resultatmål

Resultatmål
Tidsramme
Country-specific differences of the physical and psychological impact of the COVID-19 pandemic
Tidsramme: Before the COVID-19 pandemic vs. since the COVID-19 pandemic
Before the COVID-19 pandemic vs. since the COVID-19 pandemic
Differences in psychological impact in obese patients pre- and post-bariatric surgery
Tidsramme: Before the COVID-19 pandemic vs. since the COVID-19 pandemic
Before the COVID-19 pandemic vs. since the COVID-19 pandemic
Differences in psychological impact between obese patients with and without COVID-19 infection
Tidsramme: Before the COVID-19 pandemic vs. since the COVID-19 pandemic
Before the COVID-19 pandemic vs. since the COVID-19 pandemic

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Sponsor

Universitätsklinikum Hamburg-Eppendorf

Samarbeidspartnere

King's College Hospital NHS Trust

Etterforskere

  • Hovedetterforsker: Pia Roser, MD, Medical University Hospital Hamburg-Eppendorf

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart (Faktiske)

1. desember 2021

Primær fullføring (Forventet)

1. desember 2022

Studiet fullført (Forventet)

1. desember 2022

Datoer for studieregistrering

Først innsendt

19. mars 2022

Først innsendt som oppfylte QC-kriteriene

28. mars 2022

Først lagt ut (Faktiske)

31. mars 2022

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

31. mars 2022

Siste oppdatering sendt inn som oppfylte QC-kriteriene

28. mars 2022

Sist bekreftet

1. mars 2022

Mer informasjon

Begreper knyttet til denne studien

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

  • 2021-100673

Plan for individuelle deltakerdata (IPD)

Planlegger du å dele individuelle deltakerdata (IPD)?

NEI

Legemiddel- og utstyrsinformasjon, studiedokumenter

Studerer et amerikansk FDA-regulert medikamentprodukt

Nei

Studerer et amerikansk FDA-regulert enhetsprodukt

Nei

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