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Mental Fatigue Effects on Posture and Spinal Reflexes

15. juni 2026 oppdatert av: Gürsu Sayar, Izmir Bakircay University

Effects of Mental Fatigue on Posture and Spinal Reflexes Modulations

This randomized crossover study investigates the effects of mental fatigue on postural control and spinal reflex excitability in healthy physically active adults aged 18-35 years. Participants will complete two experimental conditions: a mentally fatiguing Stroop task and a control condition involving passive documentary watching, separated by at least 48 hours. Postural control will be assessed using force plate measures of center of pressure displacement during bipedal and unipedal stance, with and without concurrent cognitive dual-tasking. In parallel, spinal reflex excitability will be evaluated using H-reflex recordings from the triceps surae muscles across sitting and standing postures.

The primary aim is to determine whether mental fatigue increases postural sway, particularly in more challenging balance conditions such as single-leg stance. The secondary aim is to examine whether mental fatigue alters the normal modulation of spinal reflex excitability across progressively demanding postural tasks. Additional biomechanical and neuromuscular measures, including EMG activity and hip kinematics, will be recorded to provide insight into underlying control mechanisms.

The study will include approximately 26 participants, with each serving as their own control. Data will contribute to understanding how cognitive fatigue influences balance control and spinal-level neuromuscular regulation.

Studieoversikt

Status

Har ikke rekruttert ennå

Forhold

Intervensjon / Behandling

Studietype

Intervensjonell

Registrering (Antatt)

26

Fase

  • Ikke aktuelt

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiekontakt

Studiesteder

  • Belgia
    • Pleinlaan 2
      • Brussels, Pleinlaan 2, Belgia, 1050

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

  • Voksen

Tar imot friske frivillige

Ja

Beskrivelse

Inclusion Criteria:

  • Healthy participants aged between 18 and 35 years
  • Recreational active

Exclusion Criteria:

  • Previous major lower limb injury (last 6 months)
  • Present neurological or musculoskeletal disorders
  • Involvement in another concurrent physical or cognitive intervention study

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

  • Primært formål: Grunnvitenskap
  • Tildeling: Randomisert
  • Intervensjonsmodell: Crossover-oppdrag
  • Masking: Enkelt

Våpen og intervensjoner

Deltakergruppe / Arm
Intervensjon / Behandling
Eksperimentell: Control Condition
Participants watch a 60-minute neutral documentary of their choice. This condition is designed to control for time, visual input, and arousal without inducing mental fatigue. Postural control and spinal reflex excitability are assessed immediately before and after the task.
Atferdsmessig: Control Condition
Participants watch a 60-minute neutral documentary of their choice. This condition is designed to match the mental fatigue intervention in duration and general sensory engagement without inducing cognitive fatigue. No cognitive task performance is required. Subjective mental fatigue is assessed at equivalent time points using a visual analogue scale.
Eksperimentell: Mental Fatigue Condition
Participants complete a 60-minute computerized Stroop task designed to induce mental fatigue. The task involves continuous performance of color-word interference trials adjusted to individual capacity. Postural control and spinal reflex excitability are assessed immediately before and after the task.
Atferdsmessig: Mental Fatigue Induction
Participants complete a 60-minute computerized Stroop color-word task designed to induce mental fatigue. The task consists of repeated incongruent stimuli requiring rapid and accurate responses, with difficulty individualized based on a prior maximal Stroop performance test. Performance (reaction time and accuracy) is continuously recorded. Subjective mental fatigue is assessed intermittently during the task using a visual analogue scale.

Hva måler studien?

Primære resultatmål

Resultatmål
Tiltaksbeskrivelse
Tidsramme
Center of Pressure (CoP) Displacement (Postural Sway)
Tidsramme: Pre-intervention and immediately post-intervention (each experimental session)
Postural sway will be assessed using center of pressure (CoP) displacement area and oscillation parameters measured during bipedal and unipedal stance on a force plate. Higher values indicate greater postural instability. Comparisons will be made between mental fatigue and control conditions, pre- and post-intervention.
Pre-intervention and immediately post-intervention (each experimental session)
Subjective Mental Fatigue
Tidsramme: During intervention (every 15 minutes) and immediately post-intervention
Subjective mental fatigue will be assessed using a visual analog scale (VAS) ranging from 0 (no fatigue) to 100 (extreme fatigue).
During intervention (every 15 minutes) and immediately post-intervention

Sekundære resultatmål

Resultatmål
Tiltaksbeskrivelse
Tidsramme
Spinal Reflex Excitability (H-reflex Modulation)
Tidsramme: Pre-intervention and immediately post-intervention across sitting, bipedal stance, and unipedal stance conditions
Spinal reflex excitability will be assessed using H-reflex amplitude (H50 and Hmax), normalized to maximal M-wave (Mmax), recorded from the triceps surae muscles (soleus, medial gastrocnemius, lateral gastrocnemius) during sitting, bipedal stance, and unipedal stance. Changes will be compared between mental fatigue and control conditions.
Pre-intervention and immediately post-intervention across sitting, bipedal stance, and unipedal stance conditions
Surface Electromyography (EMG) Activity of Postural Muscles
Tidsramme: Continuous recording during postural tasks, pre-intervention and immediately post-intervention (each condition)
Muscle activation will be assessed using root mean square (RMS) electromyography (EMG) activity recorded from the soleus, medial gastrocnemius, lateral gastrocnemius, tibialis anterior, vastus medialis, and multifidus muscles, normalized to maximal M-wave (MMAX).
Continuous recording during postural tasks, pre-intervention and immediately post-intervention (each condition)
Hip / Leg Movement (IMU Angular Velocity)
Tidsramme: Pre-intervention and immediately post-intervention during bipedal and unipedal stance
Hip and leg movements will be assessed using inertial measurement unit (IMU) sensors placed at the proximal femoral epicondyle. Outcome is the resultant angular velocity across movement axes during postural tasks.
Pre-intervention and immediately post-intervention during bipedal and unipedal stance

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Sponsor

Izmir Bakircay University

Samarbeidspartnere

Vrije Universiteit Brussel
University of Franche-Comté

Etterforskere

  • Studieleder: Bart Roelands, Professor, Vrije Universiteit Brussel

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart (Antatt)

1. juli 2026

Primær fullføring (Antatt)

1. september 2026

Studiet fullført (Antatt)

1. desember 2026

Datoer for studieregistrering

Først innsendt

11. juni 2026

Først innsendt som oppfylte QC-kriteriene

15. juni 2026

Først lagt ut (Faktiske)

16. juni 2026

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

16. juni 2026

Siste oppdatering sendt inn som oppfylte QC-kriteriene

15. juni 2026

Sist bekreftet

1. juni 2026

Mer informasjon

Begreper knyttet til denne studien

Nøkkelord

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

  • MFspinal

Plan for individuelle deltakerdata (IPD)

Planlegger du å dele individuelle deltakerdata (IPD)?

NEI

IPD-planbeskrivelse

Individual participant data will not be shared. Due to the sensitive nature of physiological and health-related data and GDPR restrictions, data access will be limited to the study investigators. De-identified aggregated results will be reported in publications.

Legemiddel- og utstyrsinformasjon, studiedokumenter

Studerer et amerikansk FDA-regulert medikamentprodukt

Nei

Studerer et amerikansk FDA-regulert enhetsprodukt

Nei

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