The Impaction of Exercise Training on Bone Mineral Density in Patients After Total Knee Arthroplasty
8 de novembro de 2017 atualizado por: Robert Wen-Wei Hsu, Chang Gung Memorial Hospital
Rehabilitation after total knee arthroplasty (TKA) should consider control of postoperative pain and swelling, protection of the healing graft, restoration of full range of motion symmetric to the contralateral knee, strengthening of the muscles that stabilize the knee, hip, and trunk, enhancing neuromuscular control, and a gradual progression to functional activities that are required for return to the normal daily life.
The effects of concomitant injuries and surgical procedures must also be considered in planning an individualized rehabilitation program.
However, it is still unclear regarding the optimal exercise prescription after TKA.
In the current study, the investigators plan to develop an exercise protocol and evaluate the result in a multidisciplinary approach, i.e. bone mineral density assessment.
The exercise prescription consisted of cyclic exercise, aerobic exercise and resistant training exercise for first, second and third year, respectively.
Cyclic exercise is advantaged safety and effectiveness of hydraulic resistance equipment, as well as the exercise can be quantitatively determined.
Aerobic exercise is privileged by the cardiopulmonary endurance improvement, along with muscle strengthening in the associated muscle groups.
Resistance exercise is specified for the indicated muscle groups, especially knee extensors, flexors, ankle plantar flexor and dorsi flexor in TKA reconstructed patients.
The investigators hypothesis that using this cyclic exercise process can improve the body composition, muscle strength, bone mass density, level of oxidative damage indicators, gait performance, quality of life, knee joint range of motion, function of cardiopulmonary and fitness.
This project will establish the scientific basis for rehabilitation protocol involving knee surgery.
Visão geral do estudo
Status
Concluído
Condições
Intervenção / Tratamento
Tipo de estudo
Intervencional
Inscrição (Real)
110
Estágio
- Não aplicável
Contactos e Locais
Esta seção fornece os detalhes de contato para aqueles que conduzem o estudo e informações sobre onde este estudo está sendo realizado.
Locais de estudo
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Chiayi City, Taiwan, 613
- Sports Medicine Center, Chang Gung Memorial Hospital
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Critérios de participação
Os pesquisadores procuram pessoas que se encaixem em uma determinada descrição, chamada de critérios de elegibilidade. Alguns exemplos desses critérios são a condição geral de saúde de uma pessoa ou tratamentos anteriores.
Critérios de elegibilidade
Idades elegíveis para estudo
65 anos a 85 anos (Adulto mais velho)
Aceita Voluntários Saudáveis
Não
Gêneros Elegíveis para o Estudo
Tudo
Descrição
Inclusion Criteria:
- The inclusion criteria of this study were the patients diagnosed with serious osteoarthritis (OA) and recommended to receive TKA surgery.
Exclusion Criteria:
- The exclusion criteria were the patients with Diabetes, Neuromusculoskeletal disorder, severe chronic disease, history of fracture of a lower limb, artificial limb, and unsuitable for exercise training
Plano de estudo
Esta seção fornece detalhes do plano de estudo, incluindo como o estudo é projetado e o que o estudo está medindo.
Como o estudo é projetado?
Detalhes do projeto
- Finalidade Principal: Ciência básica
- Alocação: Não randomizado
- Modelo Intervencional: Atribuição Paralela
- Mascaramento: Dobro
Armas e Intervenções
Grupo de Participantes / Braço |
Intervenção / Tratamento |
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Sem intervenção: Control
TKA patients without exercise intervention
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Experimental: Exercise
TKA patients with exercise intervention ( cyclic exercise, aerobic exercise and resistant training exercise )
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cyclic exercise, aerobic exercise and resistant training exercise
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O que o estudo está medindo?
Medidas de resultados primários
Medida de resultado |
Descrição da medida |
Prazo |
|---|---|---|
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Change from baseline bone mineral density
Prazo: pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
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Bone mineral density measurement is measured by dual-energy x-ray absorptiometry (DXA).
Measurements are made over the lumbar spine and over the upper part of the hip and the measurement is assessed at pre-operation, three month, six month and nine month after operation, and twelve-month follow-up.
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pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
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Medidas de resultados secundários
Medida de resultado |
Descrição da medida |
Prazo |
|---|---|---|
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Change from baseline lower extremity muscle strength
Prazo: pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
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Lower extremity muscle strength, including extension and flexion of the hip, knee and ankle were tested by the HUMAC NORM system (CSMi, Stoughton, MA) with the eccentric/concentric contraction mode at an angular velocity of 60 degrees/s.Isokinetic tests were performed five times for each participant, and each test was separated by a rest period of 3 min.
The participants are assessed at pre-operation, three month, six month and nine month after operation, and twelve-month follow-up and received verbal encouragement during the exertion of peak torque.
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pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
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Motion analysis
Prazo: pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
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Gait analysis by VICON three-dimensional, 8-camera motion capture system.The outcome measurement is assessed at pre-operation, three month, six month and nine month after operation, and twelve-month follow-up.
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pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
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Change from baseline SF-36 questionnaire assessment
Prazo: pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
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SF-36 consists of eight scaled scores, which are the weighted sums of the questions in their section.
Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight.
The lower score the more disability.
The higher the score the less disability.
Eight sections including physical function, role limitation due to physical problems, bodily pain, general health, vitality, social functioning, role limitation due to emotional problems, and mental health.
Additionally, the eight health domains can be used to provide a physical component summary and mental component summary score.
The outcome measurement is assessed at pre-operation, three month, six month and nine month after operation, and twelve-month follow-up.
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pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
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Change from baseline KOOS questionnaire assessment
Prazo: pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
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KOOS contains 5 subscales with a total of 42 items: 1) pain, 2) other symptoms, 3) function in daily living (ADL), 4) function in sport and recreation and 5) knee-related quality of life.
Each question receives a score from 0 to 4 and the scores are transformed to a 0-100 score (0, extreme symptoms, 100, no symptoms).
The User's Guide, is available from www.koos.nu.
The outcome measurement is assessed at pre-operation, three month, six month and nine month after operation, and twelve-month follow-up.
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pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
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Physical fitness---6-minutes' walk test
Prazo: pre-operation; three month , six month and nine month after operation; twelve-month follow-up
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The 6-minutes' walk test measures the distance an individual is able to walk over a total of 6 minutes on a hard, flat surface.
The goal is for the individual to walk as far as possible in 6 minutes and is assessed at pre-operation, three month, six month and nine month after operation, and twelve-month follow-up.
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pre-operation; three month , six month and nine month after operation; twelve-month follow-up
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Physical fitness---2.44 m up and go
Prazo: pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
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The 2.44 m up and go test indicates the level of the participant's motor agility and dynamic balance and is assessed at pre-operation, three month, six month and nine month after operation, and twelve-month follow-up.
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pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
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Physical fitness---30-sec sit to stand
Prazo: pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
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30-sec sit to stand (times in 30sec) is assessed lower body strength, needed for numerous tasks such as climbing stairs, walking and getting out of a chair.
Also reduces the chance of falling.
Number of full stands that can be completed in 30 seconds with arms folded across chest and is assessed at pre-operation, three month, six month and nine month after operation, and twelve-month follow-up.
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pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
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Colaboradores e Investigadores
É aqui que você encontrará pessoas e organizações envolvidas com este estudo.
Patrocinador
Investigadores
- Investigador principal: Robert Wen-Wei HSU, MD, Sports Medicine Center, Chang Gung Memorial Hospital, Chiayi
Publicações e links úteis
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Datas de registro do estudo
Essas datas acompanham o progresso do registro do estudo e os envios de resumo dos resultados para ClinicalTrials.gov. Os registros do estudo e os resultados relatados são revisados pela National Library of Medicine (NLM) para garantir que atendam aos padrões específicos de controle de qualidade antes de serem publicados no site público.
Datas Principais do Estudo
Início do estudo (Real)
1 de outubro de 2013
Conclusão Primária (Real)
31 de outubro de 2017
Conclusão do estudo (Real)
31 de outubro de 2017
Datas de inscrição no estudo
Enviado pela primeira vez
18 de setembro de 2016
Enviado pela primeira vez que atendeu aos critérios de CQ
7 de outubro de 2016
Primeira postagem (Estimativa)
10 de outubro de 2016
Atualizações de registro de estudo
Última Atualização Postada (Real)
9 de novembro de 2017
Última atualização enviada que atendeu aos critérios de controle de qualidade
8 de novembro de 2017
Última verificação
1 de novembro de 2017
Mais Informações
Termos relacionados a este estudo
Termos MeSH relevantes adicionais
Outros números de identificação do estudo
- CORPG6C0021-23
Plano para dados de participantes individuais (IPD)
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INDECISO
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