The Impact of Perioperational Malnutrition on the Cost on Gastroenterological Cancer Patients
Malnutrition and Its Impact on the Perioperational Hospitalization Cost: A Prospective, Cohort Study on Gastroenterological Cancer Patients
Undernutrition is a state marked by energy and/or protein intake deficiency or mal-absorption, and is often described as protein energy malnutrition (PEM). Malnutrition is common in hospitalized patients worldwide. The prevalence of malnutrition in hospitalized patients range from 20% - 50%, depends on the varieties of diseases, health system, population and assessment tools. It is well documented in Western countries that malnutrition affects clinical outcomes negatively. Compared with well-nourished patients, patients with malnutrition stay longer in hospitals and related cost is significantly higher.
There is increasing evidence which indicates that appropriate nutrition support (e.g., standardized nutrition screening procedures, delivering nutrients with appropriate path, etc) may improve clinical outcome on malnutrition, along with cost saving.
To date, there is no study to document specifically the impact of malnutrition and related nutrition support on the health economics in China. Considering China now is on its way to establish public health security system and a diagnosis-related grouping system, the understanding of the cost effectiveness of nutrition support under the current clinical conditions is crucial.
This study aims to investigate the prevalence of perioperational malnutrition in gastroenterological cancer patient, the nutrition support status and related health economic effects.
研究概览
研究类型
注册 (预期的)
联系人和位置
学习地点
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Beijing
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Beijing、Beijing、中国、100730
- 招聘中
- Peking Union Medical College Hospital
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接触：
- Wei Chen, M.D
- 电话号码：86 10 65294095
- 邮箱：txchenwei@gmail.com
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接触：
- Hua Jiang, M.D
- 电话号码：86 28 86741981
- 邮箱：cdjianghua@gmail.com
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首席研究员：
- Wei Chen, M.D
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Age 18 or older
- With gastroenterological cancer
- Will receive resectional operation
- Consent informed
Exclusion Criteria:
- With severly cardiac, pulmonary, liver or renal disease
- With endocrine or metabolic disease
- With dyslipidemia
- Without consent
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
|---|
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Malnutrition cohort
The patients with undernutrition
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Well nourished cohort
Patient that well nourished and without undernutrition
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研究衡量的是什么？
主要结果指标
结果测量 |
大体时间 |
|---|---|
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Cost
大体时间：30 days after operation
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30 days after operation
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次要结果测量
结果测量 |
大体时间 |
|---|---|
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Mortality
大体时间：30 days after operation
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30 days after operation
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Infectious morbidity
大体时间：30 days after operation
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30 days after operation
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Length of hospitalization
大体时间：30 days after operation
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30 days after operation
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合作者和调查者
调查人员
- 研究主任：Wei Chen, M.D、Peking Union Medical College Hospital
- 学习椅：Chongmei Lu, M.D、Peking Union Medical College Hospital
出版物和有用的链接
一般刊物
- Robinson G, Goldstein M, Levine GM. Impact of nutritional status on DRG length of stay. JPEN J Parenter Enteral Nutr. 1987 Jan-Feb;11(1):49-51. doi: 10.1177/014860718701100149.
- Norman K, Pichard C, Lochs H, Pirlich M. Prognostic impact of disease-related malnutrition. Clin Nutr. 2008 Feb;27(1):5-15. doi: 10.1016/j.clnu.2007.10.007. Epub 2007 Dec 3.
- Correia MI, Campos AC; ELAN Cooperative Study. Prevalence of hospital malnutrition in Latin America: the multicenter ELAN study. Nutrition. 2003 Oct;19(10):823-5. doi: 10.1016/s0899-9007(03)00168-0.
- Lochs H, Allison SP, Meier R, Pirlich M, Kondrup J, Schneider S, van den Berghe G, Pichard C. Introductory to the ESPEN Guidelines on Enteral Nutrition: Terminology, definitions and general topics. Clin Nutr. 2006 Apr;25(2):180-6. doi: 10.1016/j.clnu.2006.02.007. Epub 2006 May 11.
研究记录日期
研究主要日期
学习开始
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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