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Taking Action Together- A Diabetes Prevention Program (TAT)

2011年5月3日 更新者:University of California, Berkeley

Taking Action Together: Development, Implementation and Evaluation of Community-Based Programs That Aims to Reduce Risk of Type 2 Diabetes in High BMI African American Children.

The purpose of this study was to determine whether once-weekly exposure to a program that fostered self-esteem building, and improvements in nutrition and physical activity behaviors would reduce risk of type 2 diabetes in overweight, inner-city, African American children when compared to a control group.

研究概览

详细说明

In the United States and, indeed, worldwide the prevalence of overweight and obesity has increased at an unprecedented rate. Concomitant with this demographic change are increases in diseases including type 2 diabetes, cardiovascular disease and some cancers that are associated with body fatness. Strategies to reduce body weight have been largely unsuccessful, making it unlikely that our population will be made healthy simply by recommending that overweight people reduce their body fatness. There is evidence, however, that the impact of body fat on human health can be significantly attenuated by potentially achievable strategies. Such strategies require adequate intakes of essential nutrients, regular physical activity and strong self-esteem. The goal of the project is to reduce the risk of type 2 diabetes mellitus (T2DM) in overweight 9- to 10-year-old African American children through a multi-component community-based program. The specific objectives are to (1).Implement a randomly controlled 2-phase intervention involving a 2-week summer camp, and weekly & monthly reinforcement sessions over 2 years, that include nutrition education, physical activity promotion, and self-esteem and self-efficacy building and (2) Test effectiveness of the program after 1 and 2 years of intervention on insulin sensitivity, the primary outcome, and on secondary outcomes including body fatness, dietary intakes, physical activity, and self-esteem. Identifying an effective, community-based program that could reduce risk of type 2 diabetes in high-risk children would promote health, reduce disease and reduce health-care costs in the future.

研究类型

介入性

注册 (实际的)

240

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

    • California
      • Oakland、California、美国、94612
        • YMCA of the East Bay, Oakland, CA 94612

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

9年 至 11年 (孩子)

接受健康志愿者

不

有资格学习的性别

全部

描述

Inclusion Criteria:

  • Child age of 9-10 yr old at baseline
  • Child BMI at least 85th percentile when matched for age and gender
  • Able and willing to participate in normal daily activities
  • Living in inner-city regions of Oakland CA

Exclusion Criteria:

  • Fasting blood glucose of 120 mg/dl or higher
  • Diagnosis of diabetes or other central metabolic disease
  • Taking medications that interfere with or treat main study outcomes

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:预防
  • 分配:非随机化
  • 介入模型:并行分配
  • 屏蔽:单身的

武器和干预

参与者组/臂
干预/治疗
实验性的:Level of intervention intensity

High Intensity: Behavioral Experimental:Participating children were invited to attend a 2 week summer day camp at the beginning of each intervention year, and to attend a weekly, 2 hr interactive session for children. Activities provided hand-on experiences preparing and tasting healthy food alternatives, engaging in a range of physical activities and self-esteem boosting via activities that promoted communication and positive behavioral development.

Active Comparator: Low-intensity Participants were provided with educational materials 4 times yearly.

High-intensity intervention, Experimental. Participating children were invited to attend a 2 week summer day camp at the beginning of each intervention year, and to attend a weekly, 2 hr interactive session for children. Activities provided hand-on experiences preparing and tasting healthy food alternatives, engaging in a range of physical activities and self-esteem boosting via activities that promoted communication and positive behavioral development.
Low-intensity intervention, Active comparator. Participants were provided with educational materials 4 times yearly.

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
1 Year change in insulin resistance via HOMA-IR
大体时间:Change during first year
Baseline HOMA-IR minus Year 1 HOMA-IR
Change during first year
2 year change in insulin resistance via HOMA-IR
大体时间:Change during 2 years
Baseline HOMA-IR minus Year 2 HOMA-IR
Change during 2 years

次要结果测量

结果测量
大体时间
Change in dietary intakes of energy, fat, carbohydrate and selected essential nutrients. Change in minutes/day spend in moderate- and high-intensity physical activity. Improvement or stabilization of self-esteem.
大体时间:3years
3years

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 首席研究员:Sharon E Fleming, PhD、University of California, Berkeley

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

一般刊物

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2005年3月1日

初级完成 (实际的)

2008年8月1日

研究完成 (实际的)

2009年12月1日

研究注册日期

首次提交

2009年12月23日

首先提交符合 QC 标准的

2009年12月23日

首次发布 (估计)

2009年12月24日

研究记录更新

最后更新发布 (估计)

2011年5月4日

上次提交的符合 QC 标准的更新

2011年5月3日

最后验证

2007年3月1日

更多信息

与本研究相关的术语

其他研究编号

  • USDA 2004-35215-14250

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