Optical Biometry and Spherical Aberration in Ametropic and Emmetropic Eyes
Aberrations play a significant role in the visual process and can be divided in lower-order and higher-order aberrations. The former can be measured using the commercially available IOL Master (Carl Zeiss Meditec AG, Germany) and have profound influence on visual acuity. Higher-order aberrations do not significantly influence visual acuity but affect the quality of vision and can cause halos, double vision, and night vision disturbances.
Background Cataract surgery has become a routine procedure in the developed countries. During this surgery, a foldable intraocular lens is usually inserted into the capsular bag. However, these lenses do not account for individual optical biometry data or aberrations. Therefore, it is important to provide data for ametropic and emmetropic eyes as this information might improve future intraocular lens design and lead to individually adapted lenses for yielding optimal visual acuity and quality results.
The aim of the present study is to clarify the correlation between refractive errors/axial eye length and spherical aberrations of the cornea.
研究概览
研究类型
注册 (实际的)
联系人和位置
学习地点
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Vienna、奥地利、1090
- Department of Clinical Pharmacology, Medical University of Vienna
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- men and women aged between 40 and 60 years
- normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
- normal ophthalmic findings unless the investigator considers an abnormality to be clinically irrelevant
Exclusion Criteria:
- presence of any corneal or retinal disease
- Dry eye syndrome
- high astigmatism (>1 diopter)
- history of refractive surgery
- abuse of alcoholic beverages
- participation in a clinical trial in the 3 weeks preceding the study
- symptoms of a clinically relevant illness in the 3 weeks before the study day
- pregnancy
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
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Cohort 1
40 subjects with high grarde myopia ranging from -10 diopters to -4.01 diopters
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Cohort 2
40 subjects with moderate myopia ranging from -4 diopters to -1.01 diopter
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Cohort 3
40 subjects with emmetropia, -1 diopter to +1 diopter
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Cohort 4
40 subjects with hyperopia, +1.01 diopter and more
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研究衡量的是什么?
主要结果指标
结果测量 |
大体时间 |
|---|---|
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Axial eye length
大体时间:1 day
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1 day
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次要结果测量
结果测量 |
大体时间 |
|---|---|
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Refractive error
大体时间:1 day
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1 day
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Corneal radius
大体时间:1 day
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1 day
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Pupil diameter
大体时间:1 day
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1 day
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Anterior chamber depth
大体时间:1 day
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1 day
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Anterior corneal topography
大体时间:1 day
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1 day
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Corneal thickness map
大体时间:1 day
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1 day
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合作者和调查者
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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