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Comprehensive Exercise Training Program During Hospitalization for an Acute CF Exacerbation

2015年6月27日 更新者:University of Alabama at Birmingham

The Efficacy of a Standardized Exercise Protocol in Inpatient Care of Patients With Cystic Fibrosis

This protocol was designed to assess if when subjects with CF are admitted to the hospital for a pulmonary exacerbation if a comprehensive exercise program (moderate to high intensity aerobic, resistance, flexibility and balance exercises) was superior to our "usual care intervention (30 min/day of self selected mode and intensity of exercise) in improving aerobic capacity, muscle strength/power, flexibility and balance.

研究概览

详细说明

This protocol was designed to assess if when subjects with CF are admitted to the hospital for a pulmonary exacerbation if a comprehensive exercise program (moderate to high intensity aerobic, resistance, flexibility and balance exercises) was superior to our "usual care intervention (30 min/day of self selected mode and intensity of exercise) in improving aerobic capacity, muscle strength/power, flexibility and balance.

The experimental group will participate in the following regime:

Day 1 - Evaluation including standardized tests and measures: If Day 1 is a M,W, F, day 2 will constitute: aerobic exercise between 20-30 minutes based on patient tolerance using the appropriate RPE scale (13-15 on Borg with patients ages 13-21, and 6-8 on pictoral CERT with patients ages 6-12)to ensure correct intensity. Choices will include treadmill, stationary bike, game bike, or ambulating at varying intensities throughout hospital; Balance Activities: Standing on bosu ball while performing UE activity (throwing, catching with another ball, Frisbee, etc.). Standing on one leg or B LE's will be determined by patients currently level.

If Day 1 is a Tuesday or Thursday, day 2 will constitute: 5-10 minutes of aerobic activity at warm up level (11-13 on Borg, and 4-6 on PCERT)x resistance training for UE: biceps, triceps, lattisimus, rhomboids/mid-trap, thoracic expansion exercises, and other muscles based on patient needs; resistance training for LE: quadriceps, hamstrings, gluteals (especially maximus and medius), and other muscles depending on patient need, core and abdominal strengthening, Stretches for flexibility depending on the patients individual needs: Thoracic expansion stretches will be done with every pt. supine and sidelying. Stretches are held for 10 seconds and repeated 10 times, Hamstring stretches will be performed if pt unable to reach line with sit and reach test.

研究类型

介入性

注册 (实际的)

23

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

    • Alabama
      • Birmingham、Alabama、美国、35233
        • University of Alabama at Birmimgham

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

6年 至 21年 (孩子、成人)

接受健康志愿者

不

有资格学习的性别

全部

描述

Inclusion Criteria:

  • age 6 to 21 years
  • admission for an acute Cystic fibrosis (CF) exacerbation
  • forced expiratory volume in 1 s (FEV1) of < 60% of predicted at admission

Exclusion Criteria:

  • medically unstable as deemed by the attending physician
  • had completed both arms of the present study

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:治疗
  • 分配:随机化
  • 介入模型:交叉作业
  • 屏蔽:无(打开标签)

武器和干预

参与者组/臂
干预/治疗
实验性的:Comprehensive exercise program
Moderate to high intensity aerobic, resistance, flexibility, posture and balance exercise program
有源比较器:Usual care exercise
30 minutes/day of self selected mode and intensity of aerobic exercise

研究衡量的是什么?

主要结果指标

结果测量
大体时间
Aerobic capacity following intervention of a comprehensive excercise training program
大体时间:Participants will be followed for the duration of hospital stay, average number of days 10 (range 4 - 20 days)
Participants will be followed for the duration of hospital stay, average number of days 10 (range 4 - 20 days)

次要结果测量

结果测量
措施说明
大体时间
Muscle strength and power following intervention of a comprehensive excercise training program
大体时间:Participants will be followed for the duration of hospital stay, average number of days 10 (range 4 - 20 days)
Assessed with arm curl test, partial curl up test, timed 10 repetition sit to stand test
Participants will be followed for the duration of hospital stay, average number of days 10 (range 4 - 20 days)
Posture/flexibility following intervention of a comprehensive excercise training program
大体时间:Participants will be followed for the duration of hospital stay, average number of days 10 (range 4 - 20 days)
Assessed with humeral distance, shoulder flexion range of motion, and hamstring length
Participants will be followed for the duration of hospital stay, average number of days 10 (range 4 - 20 days)
Balance following intervention of a comprehensive excercise training program
大体时间:Participants will be followed for the duration of hospital stay, average number of days 10 (range 4 - 20 days)
Assessed with the pediatric Berg balance scale
Participants will be followed for the duration of hospital stay, average number of days 10 (range 4 - 20 days)

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 首席研究员:John D Lowman, PT, PhD、University of Alabama at Birmingham

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2008年4月1日

初级完成 (实际的)

2008年10月1日

研究完成 (实际的)

2008年10月1日

研究注册日期

首次提交

2012年12月21日

首先提交符合 QC 标准的

2012年12月30日

首次发布 (估计)

2013年1月3日

研究记录更新

最后更新发布 (估计)

2015年6月30日

上次提交的符合 QC 标准的更新

2015年6月27日

最后验证

2012年12月1日

更多信息

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

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