Determination of Protein Requirements in Pregnancy
Determination of Protein Requirements in Healthy Pregnant Women Using Indicator Amino Acid Oxidation Technique
Protein is an essential part of our diet. It is used to build muscle and body tissue, send signals throughout our body and to support the immune system. Dietary protein is even more crucial during pregnancy as it is needed for healthy growth and development of the baby. There is very minimal data available on how much additional protein is required during pregnancy. Current recommendations are based on older techniques such as nitrogen balance studies of non-pregnant adults and minimally based on pregnancy specific data. There is no scientific information regarding the amount of protein needed during different stages of pregnancy.
The investigators hypothesize that the current recommendations of protein intake during pregnancy are underestimated.
The goal of this study is to measure protein requirement in healthy pregnant women (19-35y)using a more quick and modern technique called the indicator amino acid oxidation technique (IAAO).
研究概览
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
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British Columbia
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Vancouver、British Columbia、加拿大、V5Z4H4
- Child & Family Research Institute
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:Healthy pregnant women
- Singleton pregnancy
- Maternal age 19-35y
- In good health (free of chronic/acute disease,full range of physical mobility)
- Healthy pre-pregnancy body mass index
Exclusion Criteria:Women
- not pregnant
- Pregnant with more than one child
- Singleton pregnancy outside the age range of 19-35y
- Not in good health or have a metabolic, neurological, genetic, or immune disorder, including gestational diabetes or anemia
- smoke or consume alcohol during their pregnancy
- classified as underweight (<18.5 kg/m2), overweight (25-30 kg/m2) or obese (>30 kg/m2)
- allergic to eggs and egg protein
- severe nausea/vomiting throughout their pregnancy
学习计划
研究是如何设计的？
设计细节
- 主要用途：基础科学
- 分配：不适用
- 介入模型：单组作业
- 屏蔽：单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：Protein Intake
Dietary supplement:Protein intake
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Oral consumption of Eight hourly experimental meals- Includes 4 tracer-free experimental meals containing a mixture of free amino acids, calories from a flavored liquid and protein free cookies and 4- labeled amino acid experimental meals.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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13 Carbon dioxide production
大体时间：8 hours (1 study day)
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Urine and breath samples will be collected during the study to measure the rate of oxidation of tracer in expired breath and flux by enrichment in urine.
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8 hours (1 study day)
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合作者和调查者
调查人员
- 首席研究员：Rajavel Elango, Ph.D、Child & Family Research Institute/University of British Columbia
出版物和有用的链接
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他研究编号
- H11-00070
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
Protein Intake的临床试验
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University of HohenheimUniversity Hospital Tuebingen完全的
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PharmanexUniversity of North Carolina, Chapel Hill完全的
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University of NebraskaInCor Heart Institute; VU University of Amsterdam完全的