DETECT and Retinal Outcomes in Hypertension
The Effects of Blood Pressure on Cognitive Function: Examining the Use of Bedside Neuropsychological Testing During Acute Hypertensive Events
研究概览
详细说明
研究类型
注册 (实际的)
联系人和位置
学习地点
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Georgia
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Atlanta、Georgia、美国、30303
- Grady Memorial Hospital
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Patients triaged to the Grady Memorial Hospital Emergency Department or Marcus Trauma Unit
- Age >18 and <65
Documented history of hypertension plus one or more of the following:
- current antihypertensive use with controlled blood pressure
- elevated Emergency Department systolic blood pressure or diastolic blood pressure
- OR -
Acutely elevated Emergency Department systolic blood pressure or diastolic blood pressure on 2 separate Emergency Department measurements in the absence of a history of hypertension
- OR -
- Normal systolic blood pressure or diastolic blood pressure in the absence of hypertension.
Exclusion Criteria:
- Non-English speaking
- Pre-visit cognitive impairment
- Physical or psychological impairments that would prohibit comprehension and completion of DETECT testing
- Inability to obtain adequate fundoscopic photos
- Acute intoxication, altered mental status, or head injury within the last 6 months
- Opiate or benzodiazepine administration by treating providers
- Clinical condition not allowing testing.
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
|---|
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controlled hypertension
hypertension with medication controlled
|
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uncontrolled hypertension
non-controlled hypertension
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hypertensive urgency
hypertensive urgency no previous history or antihypertensives
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asymptomatic normotensive
asymptomatic normotensive control group
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
DETECT neurocognitive outcome scores (Z-scores) in association with blood pressure measures and retinal pathology (isolated retinal hemorrhage, grade III/IV hemorrhagic retinopathy)
大体时间:12 months
|
We aim to determine the correlation (if any) between the severity of blood pressure and DETECT neurocognitive outcomes as well as the correlation (if any) between known Hypertensive retinal disease and DETECT neurocognitive outcomes. Appropriate statistical analysis will be performed to compare clinical retinal findings, BP values, and DETECT neurocognitive test outcomes. Subject level data will only be collected on the day of Emergency Department presentation. Subjects will not be followed after their initial enrollment. The study duration is projected for 12 months |
12 months
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次要结果测量
结果测量 |
大体时间 |
|---|---|
|
Variance of DETECT scores (Z-score) attributed to reading level
大体时间:One year study periord (12 months)
|
One year study periord (12 months)
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合作者和调查者
调查人员
- 首席研究员:Tamara Espinoza, MD、Emory University
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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