Effects of tDCS on Quadriceps Strength After Stroke (tDCS(HE))
a Controlled, Randomized Study Evaluating the Immediate Effect of One tDCS Session on Quadriceps Strength in Hemiparetic Patients.
Previous studies show that one session of tDCS allow to improve muscle strength in hemiparetic patients in anodal condition. We test a new electrods configuration : a anodale stimulation opposite to the cortical representation area of the injured hemisphere and a simultaneous stimulation opposite to the homonyme the cortical representation area of the healthy hemisphere. This approach seems to be the best relevant electrods configuration in order to restore the inter-hemispheric balance.
We hypothesis that one session of tDCS with this electrods configuration allow to improve paretic quadriceps strength in hemiparetic patients after stroke.
研究概览
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
-
-
-
Garches、法国、92380
- Raymond Poincaré Hospital
-
-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- written consent
- hemiparetic patient after stroke in chronic phase (> 6 months)
- capacity to walk with or without technical assistance
- following rehabilitation program for lower limbs
Exclusion Criteria:
- patient with bilateral brain lesion, cerebellar syndrom, and apraxia and/or aphasia
- previous orthopedic surgery in paretic lower limb (<6 moths)
- usual tDCS contraindications
- pregnant woman
学习计划
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：交叉作业
- 屏蔽：单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的：hemiplegic patient
anodal transcranial direct current stimulation
|
|
|
假比较器：patient control
Sham transcranial direct current stimulation
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
maximum voluntary isometric strength of knee extensors
大体时间：2 hours
|
The maximum voluntary isometric strength of paretic knee extensors will be evaluated with a isokinetic dynamometer, which measure peak torque.
|
2 hours
|
次要结果测量
结果测量 |
大体时间 |
|---|---|
|
Resistive peak torque during passive knee flexion
大体时间：2h
|
2h
|
|
Angle related to the resistive peak torque generation of the knee extensors
大体时间：2h
|
2h
|
|
Amplitude of the interpolation twitch
大体时间：2h
|
2h
|
|
EMG activation of the knee flexors and extensors during the strength evaluations (active and passive)
大体时间：2h
|
2h
|
|
Functional evaluation of the gait performance and balance
大体时间：2h
|
2h
|
合作者和调查者
调查人员
- 首席研究员：Roche Nicolas, MD PH、Raymond Poincaré Hospital
- 首席研究员：Bensmail Djamel, MD PH、Raymond Poincaré Hospital
出版物和有用的链接
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.