Effects of Yoga on Bone Metabolism in Premenopausal Women
2014年6月13日 更新者：Debra Bemben、University of Oklahoma
Effects of an 8-month Yoga Intervention on Bone Metabolism in Healthy Middle-aged Premenopausal Women: A Randomized Controlled Study
This study examined the effects of 8 months of Yoga training on bone density and bone turnover markers in premenopausal women, ages 35-50 years.
The style of Yoga used was power Yoga that involved postures with a jumping component.
The investigators hypothesized that the Yoga intervention would result in beneficial improvements in bone turnover markers, by increasing the bone formation marker and decreasing the bone resorption marker.
研究概览
研究类型
介入性
注册 (实际的)
47
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
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Oklahoma
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Norman、Oklahoma、美国、73019
- Department of Health and Exercise Science, University of Oklahoma
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参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
35年 至 50年 (成人)
接受健康志愿者
是的
有资格学习的性别
女性
描述
Inclusion Criteria:
- participants had not been engaged in resistance training or in Yoga exercise for at least 12 months prior to the study
- did not have chronic back or joint problems or cardiovascular disease
- not taking antihypertensive drugs or any medication that affects bone density
- not taking hormonal contraception
- they self-reported having regular menstrual cycles.
Exclusion Criteria:
- body weight more than 300 pounds
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：预防
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：Yoga group
8 months of progressive Yoga training
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8 months of Yoga training
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无干预：Control group
No training, just pre and post testing
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Change in bone mineral density from baseline to 8 months
大体时间：pre and post 8 months training
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pre and post 8 months training
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change in bone turnover markers
大体时间：pre and post 8 month intervention
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pre and post 8 month intervention
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change in tibia bone characteristics
大体时间：pre and post 8 month intervention
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changes in volumetric bone mineral density and bone strength of the non-dominant tibia assessed by peripheral Quantitative Computed Tomography (pQCT)
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pre and post 8 month intervention
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Changes in muscular strength
大体时间：pre and post 9 month intervention
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Isotonic 1 repetition maximum (1RM) for 4 lower body and 2 upper body resistance exercises
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pre and post 9 month intervention
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Change in arterial compliance
大体时间：pre and post 8 month interventon
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Arterial compliance of the large and small arteries was assessed using Pulse Contour analysis.
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pre and post 8 month interventon
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Change in Insulin-like Growth Factor-1 (IGF-I) and Insulin-like Growth Factor BP3 (IGFBP3)
大体时间：pre and post 8 month intervention
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pre and post 8 month intervention
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Daily Calcium intake
大体时间：pre and post 8 month intervention
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Calcium intake is a potential confounding variable.
Participants were encouraged to increase their calcium intakes if found to be low before the intervention began.
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pre and post 8 month intervention
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Menstrual History
大体时间：pre and post 8 month intervention
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This information was used to monitor menstrual characteristics to ensure they were still premenopausal at the post test.
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pre and post 8 month intervention
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Dietary intake
大体时间：At baseline at the same time as other outcomes, about 2 weeks before the beginning of the yoga training
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Three day dietary logs were recorded by participants before the exercise intervention.
They were analyzed for caloric intake and nutrient composition using the Diet Analysis Plus 9 software.
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At baseline at the same time as other outcomes, about 2 weeks before the beginning of the yoga training
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Change in physical activity levels
大体时间：pre and post 8 month intervention
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Physical activity levels estimated by the bone-specific physical activity (PA) questionnaire to monitor their PA outside of the intervention
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pre and post 8 month intervention
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Change in body composition
大体时间：pre and post 8 month intervention
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pre and post 8 month intervention
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 首席研究员：Debra A Bemben, PhD、Department of Health and Exercise Science, University of Oklahoma
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
一般刊物
- Phoosuwan M, Kritpet T, Yuktanandana P. The effects of weight bearing yoga training on the bone resorption markers of the postmenopausal women. J Med Assoc Thai. 2009 Sep;92 Suppl5:S102-8.
- Chan K, Qin L, Lau M, Woo J, Au S, Choy W, Lee K, Lee S. A randomized, prospective study of the effects of Tai Chi Chun exercise on bone mineral density in postmenopausal women. Arch Phys Med Rehabil. 2004 May;85(5):717-22. doi: 10.1016/j.apmr.2003.08.091.
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始
2009年9月1日
初级完成 (实际的)
2010年6月1日
研究完成 (实际的)
2012年4月1日
研究注册日期
首次提交
2014年6月9日
首先提交符合 QC 标准的
2014年6月13日
首次发布 (估计)
2014年6月16日
研究记录更新
最后更新发布 (估计)
2014年6月16日
上次提交的符合 QC 标准的更新
2014年6月13日
最后验证
2014年6月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
Yoga Group的临床试验
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Florida Atlantic UniversityNational Center for Complementary and Integrative Health (NCCIH)完全的
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Oslo University HospitalAkershus University Hospital, Lørenskog, Norway; Koc University Hospital, Istanbul, Turkey; Ataturk... 和其他合作者完全的
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Centro Hospitalar do PortoUniversity of Trás-os-Montes and Alto Douro; Foundation for Science and Technology, Portugal; Institute...招聘中
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Amsterdam UMC, location VUmcRed Cross Hospital Beverwijk完全的
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Case Western Reserve UniversityNational Institutes of Health (NIH); American Heart Association完全的