Gestational Diabetes Mellitus and Neurodevelopment in Newborns
Does Brain Functions Depend on Omega 3 Transferred to the Fetus During the Intra Uterine Life ?
The purpose of this study is to evaluate the feasibility of using a quantitative EEG method to evaluate neurodevelopment in newborns and to evaluate whether subtle neurodevelopmental deficits can be detected in newborns from mothers with gestational diabetes mellitus (GDM) compared to control newborns.
The second purpose of this study is to determine whether cord blood concentration in docosahexaenoic acid (DHA), an omega-3 fatty acid, is similar in neonates of well-controlled mothers with gestational diabetes mellitus (GDM) compared to control mothers, and to evaluate whether this contributes to neonates neurodevelopment status.
研究概览
详细说明
研究类型
注册 (实际的)
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- singleton pregnancy
- aged between 18 and 40 years
Exclusion Criteria:
- smoking,
- illicit drug consumption,
- omega-3/6 consumption,
- liver or renal disease,
- cancer
- any medical conditions affecting glucose/lipid metabolism.
学习计划
研究是如何设计的?
设计细节
- 观测模型:病例对照
- 时间观点:追溯
队列和干预
团体/队列 |
---|
GDM newborns
Newborns from gestational diabetes mellitus pregnancy
|
No GDM newborns
Newborn from a normal pregnancy
|
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Change in neurodevelopment
大体时间:At birth
|
Evaluate change in neurodevelopment with GDM
|
At birth
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Change in DHA level in cord blood
大体时间:At birth
|
Evaluate change in DHA level with GDM
|
At birth
|
合作者和调查者
调查人员
- 首席研究员:Melanie Plourde, PhD、Université de Sherbrooke
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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