To Evaluate the Effects of Omega 3 Fatty Acids in the Context of Cancer Prevention

Inclusion Criteria:

• Woman or man, aged of 18 to 65 years;
• Body mass index between 20 and 30 kg/m2;
• For women: use of effective contraception;
• Provision of signed and dated informed consent form;
• Stated willingness to comply with all study procedures and availability for the duration of the study.

Exclusion Criteria:

• Uncontrolled systolic blood pressure > 160/100 mmHg;
• For premenopausal women: pregnant women or women planning to get pregnant within 3 months or lactating women;
• For menopausal women: less than 6 months of menopause;
• Type II diabetes (controlled or uncontrolled), Type I diabetes;
• Medical history or actual severe psychiatric, severe neurologic, severe hepatic, severe pancreatic, severe kidney, severe pulmonary, severe cardiovascular or severe gastrointestinal problem;
• Thyroid disorder;
• Cancer < 3 years before the inclusion;
• Consumption of drug under prescription or over-the-counter drug or dietary supplement (including n-3 PUFA) within 1 month before the inclusion (excepted contraception);
• Consumption of fish or of omega-3 enriched eggs > 2 times per week within 1 month before the inclusion;
• Subjects who are not able to understand and follow study procedures;
• Drug addiction problem (occasional or regular consumption);
• Women who drink more than 2 glasses of alcohol per day (> 20 g of alcohol per day or > 140 g/week) or men who drink more than 3 glasses of alcohol per day (> 30 g of alcohol per day or more than 210 g/week);
• Subjects having given their blood within less than 3 months before inclusion;
• Subjects having participated to another clinical trial with an investigational product within less than 1 month before the inclusion.