The Effects of Immersive Virtual Reality-Based Exergaming Combined With Transcranial Direct Current Stimulation on Executive Functions in Healthy Older Adults
2026年5月9日 更新者：Beijing Sport University
The goal of this clinical trial is to investigate the acute effects of immersive virtual reality (VR)-based exergaming combined with transcranial direct current stimulation (tDCS) on executive functions in healthy older adults. The main questions it aims to answer are:
- Does VR-based exergaming combined with tDCS improve executive function performance in healthy older adults compared with a control condition?
- Do single interventions (tDCS alone or VR-based exergaming alone) improve executive function performance compared with the control condition?
- Does the combined intervention produce greater improvements in executive function performance than either intervention alone? Researchers will compare four intervention conditions to evaluate differences in executive function performance following each session.
Participants will:
- Complete four intervention sessions in a randomized crossover sequence, with a washout period of at least 7 days between sessions
- Receive the following intervention conditions:
- sham-tDCS + VR-video
- tDCS + VR-video
- sham-tDCS + VR-exergaming
- tDCS + VR-exergaming
- Complete executive function assessments immediately after each session, including:
- the Flanker task for inhibitory control
- the more-odd shifting task for cognitive flexibility
- the Corsi block-tapping task for working memory
研究概览
地位
尚未招聘
条件
研究类型
介入性
注册 (估计的)
24
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习联系方式
- 姓名：Mengdie Hu
- 电话号码：86+13011852188
- 邮箱：mengdie.hu0818@hotmail.com
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
是的
描述
Inclusion Criteria:
(1) Age between 60 to 70 years old; (2) Right-handed (Edinburgh Handedness Inventory (Chinese version) > 40); (3) Normal overall cognitive function (Montreal Cognitive Assessment (Beijing version) ≥ 26).
Exclusion Criteria:
(1) Musculoskeletal injury; (2) neurological/neurodegenerative disorders (e.g., Alzheimer's disease); (3) history of brain infections or cerebrovascular diseases; (4) psychiatric disorders (e.g., major depressive disorder, schizophrenia); (5) unstable or chronic medical conditions (e.g., cardiac disease, seizures (personal/family history)); (6) hearing and visual impairments (e.g., color blindness and conditions severely affecting the ability to see the screen or distinguish colors); (7) metal implants (e.g., pacemakers); (8) brain stimulation or exercise training intervention within the past 6 months; (9) failure to meet safety criteria for brain stimulation (e.g., pregnancy)
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：其他
- 分配：随机化
- 介入模型：交叉作业
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
假比较器：Sham tDCS + VR-video
Participants receive sham transcranial direct current stimulation and then watch a virtual reality video.
|
The anodal electrode is positioned over the left DLPFC (F3), and the cathodal electrode is placed over the right supraorbital area.
Sham stimulation is applied in the same locations for 20 min with only 15s ramp-up and 15s ramp-down stimulation to mimic the sensory experience of real stimulation.
For the VR-video condition, participants view a mild plant documentary called Journey of Chinese Plants through the same VR headset.
VR-video intervention consisted of four cycles of 3.5 min, each separated by a 2-min rest interval, for a total duration of 20 min
|
|
实验性的：tDCS + VR-video
Participants receive active transcranial direct current stimulation and then watch a virtual reality video.
|
For the VR-video condition, participants view a mild plant documentary called Journey of Chinese Plants through the same VR headset.
VR-video intervention consisted of four cycles of 3.5 min, each separated by a 2-min rest interval, for a total duration of 20 min
The anodal electrode is positioned over the left DLPFC (F3), and the cathodal electrode is placed over the right supraorbital area.
The transcranial direct current stimulation is applied for 20 min at an intensity of 2 mA, with 15 s ramp-up and 15 s ramp-down.
|
|
实验性的：Sham tDCS + VR-exergaming
Participants receive sham transcranial direct current stimulation combined with immersive virtual reality-based exergaming.
|
The anodal electrode is positioned over the left DLPFC (F3), and the cathodal electrode is placed over the right supraorbital area.
Sham stimulation is applied in the same locations for 20 min with only 15s ramp-up and 15s ramp-down stimulation to mimic the sensory experience of real stimulation.
For the VR-exergaming condition, participants engage in an interactive rhythm-based fitness game called PowerBeatsVR.
It immerses participants in a virtual exercise environment accompanied by dynamic musical beats, with punching and tracking movements.
The VR-exergaming consisted of four cycles of 3.5 min, each separated by a 2-min rest interval, for a total duration of 20 min
|
|
实验性的：tDCS + VR-exergaming
Participants receive active transcranial direct current stimulation combined with immersive virtual reality-based exergaming.
|
The anodal electrode is positioned over the left DLPFC (F3), and the cathodal electrode is placed over the right supraorbital area.
The transcranial direct current stimulation is applied for 20 min at an intensity of 2 mA, with 15 s ramp-up and 15 s ramp-down.
For the VR-exergaming condition, participants engage in an interactive rhythm-based fitness game called PowerBeatsVR.
It immerses participants in a virtual exercise environment accompanied by dynamic musical beats, with punching and tracking movements.
The VR-exergaming consisted of four cycles of 3.5 min, each separated by a 2-min rest interval, for a total duration of 20 min
|
研究衡量的是什么？
主要结果指标
结果测量 |
大体时间 |
|---|---|
|
Reaction time and accuracy of inhibitory control are assessed by the Flanker task.
大体时间：Immediately after the intervention.
|
Immediately after the intervention.
|
次要结果测量
结果测量 |
大体时间 |
|---|---|
|
Reaction time and accuracy of cognitive flexibility are assessed by more odds shifting task.
大体时间：Immediately after the intervention.
|
Immediately after the intervention.
|
|
Scores of working memory are assessed by the Corsi Block-Tapping Task
大体时间：Immediately after the intervention.
|
Immediately after the intervention.
|
合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (估计的)
2026年5月20日
初级完成 (估计的)
2026年6月25日
研究完成 (估计的)
2026年6月25日
研究注册日期
首次提交
2026年5月9日
首先提交符合 QC 标准的
2026年5月9日
首次发布 (实际的)
2026年5月15日
研究记录更新
最后更新发布 (实际的)
2026年5月15日
上次提交的符合 QC 标准的更新
2026年5月9日
最后验证
2026年5月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.