Effects of Bicarbonate Spring Water Immersion on Cognitive Reliability and Post-Maximal Exercise Recovery in Adolescent Rowers During Altitude Training: A Sex-Stratified Three-Arm Randomized Controlled Trial
2026年7月31日 更新者：Ziyue Ou、Macao Polytechnic University
A Sex-Stratified Block-Randomized Controlled Trial of Bicarbonate-Rich Thermal Water Immersion on Cognitive Reliability and Post-Maximal Exercise Recovery in Adolescent Rowers During Field-Based Moderate-Altitude Training
This randomized controlled trial aims to investigate the effects of hot spring bath therapy on cognitive function recovery, cerebral hemodynamics, and athletic performance in athletes undergoing altitude training.
Participants will be randomly assigned to either a hot spring intervention group, a hot water control group, or a blank control group.
The hot spring intervention group receives hot spring baths (38°C, 20 minutes) combined with altitude training; the hot water control group receives hot water baths (38°C, 20 minutes) combined with altitude training; and the blank control group receives standard recovery procedures combined with altitude training.
Primary outcome measures include cognitive performance assessments (Stroop test, psychomotor vigilance test) and cerebral hemodynamic indicators (functional near-infrared spectroscopy, transcranial Doppler ultrasound).
Secondary outcomes included exercise capacity (maximal oxygen uptake, triathlon performance, 500-meter test), blood lactate, and hematological parameters (white blood cells, neutrophils, platelets).
These findings may provide evidence for non-pharmacological interventions to enhance cognitive recovery and brain adaptation during altitude training.
研究概览
地位
完全的
研究类型
介入性
注册 (实际的)
27
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
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Yunnan
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Tengyue、Yunnan、中国
- Field altitude-training camp, approximately 1600 m
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参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 孩子
接受健康志愿者
是的
描述
Inclusion Criteria:
- Male or female aged 11-17 years- Regular endurance training (≥3 sessions/week) for ≥2 years
- No history of altitude exposure >2000m in the past 3 months
- No contraindications to hot water immersion (e.g., uncontrolled hypertension, severe cardiovascular disease, open wounds, pregnancy)
- Ability to provide written informed consent
- Willingness to abstain from other recovery modalities (e.g., massage, cryotherapy, compression garments) during the study period
- No color blindness or uncorrected visual impairment that would affect Stroop test performance
Exclusion Criteria:
- History of cardiovascular, respiratory, renal, or endocrine disorders
- Current use of medications affecting autonomic function or cognition (e.g., beta-blockers, anticholinergics, stimulants, sedatives)
- History of syncope, heat intolerance, or neurological disorders
- Acute musculoskeletal injury within the past 6 months- Regular use of sauna, hot tub, or spa within the past month- Pregnancy or breastfeeding (for female participants)
- Shift work or trans-meridian travel within 2 weeks prior to baseline assessment- Alcohol consumption >14 units/week or smoking
- History of traumatic brain injury, stroke, or psychiatric disorders
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：其他
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：双倍的
武器和干预
参与者组/臂 |
干预/治疗 |
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有源比较器：Natural Recovery Group
Control group participants will undergo the same altitude training protocol (altitude 1600 meters) for 4 weeks.
Participants underwent a 20-minute quiet seated rest at 16:00 on Tuesdays, Thursdays, and Saturdays, with ad libitum water consumption permitted and electronic devices prohibited.
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Control group participants will undergo the same altitude training protocol (altitude 1600 meters) for 4 weeks.
After each training session, participants will receive standard recovery procedures, including 20 minutes of passive rest in a thermoneutral environment (room temperature 24°C), supplemented with mild hydration and self-selected stretching.
No hydrothermal intervention will be provided.
其他名称：
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有源比较器：Hot water immersion group
The hot water immersion group will undergo a 4-week altitude training at 1600 meters above sea level.
Subjects will receive a 20-minute hot water immersion (daily tap water, 38°C±0.5°C) in a standardized indoor hot spring facility.
The immersion protocol includes partial-body immersion up to the xiphoid process (lower chest) for 20 minutes, followed by a 10-minute rest before leaving the facility.
Three times per week.
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The hot water immersion group will undergo a 4-week altitude training at 1600 meters above sea level.
Subjects will receive a 20-minute hot water immersion (daily tap water, 38°C±1°C) in a standardized indoor hot spring facility.
The immersion protocol includes whole-body immersion up to the neck for 20 minutes, followed by a 10-minute rest before leaving the facility.
Three times per week.
其他名称：
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实验性的：Hot Spring Immersion Group
The hot spring immersion group will undergo a 4-week high-altitude training at an altitude of 1600 meters.
Subjects will receive a 20-minute hot spring therapy (natural hot spring water, 38°C ± 0.5°C) in a standardized indoor hot spring facility.
The immersion protocol includes partial-body immersion up to the xiphoid process (lower chest) for 20 minutes, performed three times per week, followed by a 10-minute rest before leaving the facility.
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The hot spring immersion group will undergo a 4-week high-altitude training at an altitude of 1600 meters.
Subjects will receive a 20-minute hot spring therapy (natural hot spring water, 38°C ± 1°C) in a standardized indoor hot spring facility.
The immersion protocol includes whole-body immersion to the neck for 20 minutes, followed by a 10-minute rest before leaving the facility.
Three times per week.
其他名称：
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Psychomotor Vigilance Test (PVT)
大体时间：Baselines were measured at the formal start of the experiment, at night during the 2nd, 3rd, and 4th weeks (post-intervention) after ascending the plateau, and post-tests were conducted one week after descending the plateau.
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5-minute PVT measuring sustained attention and psychomotor vigilance.
Outcome variables: mean reciprocal response time (1/RT).
Administered via standardized software on a tablet/computer.
Unit: second.
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Baselines were measured at the formal start of the experiment, at night during the 2nd, 3rd, and 4th weeks (post-intervention) after ascending the plateau, and post-tests were conducted one week after descending the plateau.
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Stroop Test Performance
大体时间：Baselines were measured at the formal start of the experiment, at night during the 2nd, 3rd, and 4th weeks (post-intervention) after ascending the plateau, and post-tests were conducted one week after descending the plateau.
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Computerized Stroop Color-Word Test measuring executive function and cognitive inhibition.
Outcome variables: reaction time (ms).
Administered in a quiet, temperature-controlled room (22-24°C).
Unit: milliseconds (ms).
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Baselines were measured at the formal start of the experiment, at night during the 2nd, 3rd, and 4th weeks (post-intervention) after ascending the plateau, and post-tests were conducted one week after descending the plateau.
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Cerebral Oxygenation (fNIRS)
大体时间：Baseline, Week 2, Week 5
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Changes in oxygenated hemoglobin (HbO) and deoxygenated hemoglobin (HbR) in the prefrontal cortex during cognitive tasks, measured by functional near-infrared spectroscopy (fNIRS) with a multichannel system.
Outcome: relative changes in HbO and HbR concentrations.
Unit: micromolar (μM).
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Baseline, Week 2, Week 5
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Cerebral Blood Flow Velocity (TCD)
大体时间：Baseline, Week 2, Week 4
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Mean blood flow velocity in the middle cerebral artery (MCA) and anterior cerebral artery (ACA) measured by transcranial Doppler ultrasound (TCD) with 2MHz probe.
Measurements taken in supine position after 10 minutes of rest.
Outcome: mean velocity (cm/s).
Unit: centimeters/second (cm/s).
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Baseline, Week 2, Week 4
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Maximal Oxygen Uptake (VO2max)
大体时间：Baseline, Week 5
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Maximal oxygen uptake measured using a portable metabolic analyzer during a graded exercise test on a rowing ergometer.
Test protocol: incremental ramp test to exhaustion.
Unit: mL/kg/min.
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Baseline, Week 5
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1000-Meter Running Test
大体时间：Baseline, Week 3, Week4
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1000-meter maximal effort running test on a standard 400m track or treadmill.
Total completion time recorded.
Unit: seconds (s).
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Baseline, Week 3, Week4
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Peripheral Oxygen Saturation (SpO2)
大体时间：one month.
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Resting peripheral oxygen saturation measured via fingertip pulse oximeter after 10 minutes of seated rest.
Unit: percentage (%).
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one month.
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
一般刊物
- MacLeod CM. Half a century of research on the Stroop effect: an integrative review. Psychol Bull. 1991 Mar;109(2):163-203. doi: 10.1037/0033-2909.109.2.163. No abstract available.
- Laukkanen T, Khan H, Zaccardi F, Laukkanen JA. Association between sauna bathing and fatal cardiovascular and all-cause mortality events. JAMA Intern Med. 2015 Apr;175(4):542-8. doi: 10.1001/jamainternmed.2014.8187.
- Stanley J, Peake JM, Buchheit M. Consecutive days of cold water immersion: effects on cycling performance and heart rate variability. Eur J Appl Physiol. 2013 Feb;113(2):371-84. doi: 10.1007/s00421-012-2445-2. Epub 2012 Jul 3.
- Ando S, Hatamoto Y, Sudo M, Kiyonaga A, Tanaka H, Higaki Y. The effects of exercise under hypoxia on cognitive function. PLoS One. 2013 May 10;8(5):e63630. doi: 10.1371/journal.pone.0063630. Print 2013.
- Ohori T, Nozawa T, Ihori H, Shida T, Sobajima M, Matsuki A, Yasumura S, Inoue H. Effect of repeated sauna treatment on exercise tolerance and endothelial function in patients with chronic heart failure. Am J Cardiol. 2012 Jan 1;109(1):100-4. doi: 10.1016/j.amjcard.2011.08.014. Epub 2011 Sep 23.
- Buchheit M, Simpson BM, Garvican-Lewis LA, Hammond K, Kley M, Schmidt WF, Aughey RJ, Soria R, Sargent C, Roach GD, Claros JC, Wachsmuth N, Gore CJ, Bourdon PC. Wellness, fatigue and physical performance acclimatisation to a 2-week soccer camp at 3600 m (ISA3600). Br J Sports Med. 2013 Dec;47 Suppl 1(Suppl 1):i100-6. doi: 10.1136/bjsports-2013-092749.
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2026年1月25日
初级完成 (实际的)
2026年2月26日
研究完成 (实际的)
2026年3月8日
研究注册日期
首次提交
2026年5月14日
首先提交符合 QC 标准的
2026年5月19日
首次发布 (实际的)
2026年5月27日
研究记录更新
最后更新发布 (实际的)
2026年8月4日
上次提交的符合 QC 标准的更新
2026年7月31日
最后验证
2026年7月1日
更多信息
与本研究相关的术语
其他研究编号
- 202502AS100005-1
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
未定
IPD 计划说明
The current research project has not yet been completed, and the data have not been publicly released.
After publication, sharing will be decided on a case-by-case basis.
药物和器械信息、研究文件
研究美国 FDA 监管的药品
不
研究美国 FDA 监管的设备产品
不
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.