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Alleviation of Cardiometabolic Risk Factors Through Watermelon Rind

2026年5月19日 更新者:Maria Aslam、University of Lahore

Alleviation of Cardiometabolic Risk Factors Through Watermelon (Citrullus Lanatus (Thunb.) Matsum. &Amp; Nakai) Rind-based Bread Among Cardiac Patients

To collect data, written consent was obtained from the hospital and university administration. After receiving signed informed consent, the data was collected from cardiac patients.

研究概览

详细说明

The target population was adults between the ages of 35 and 65 years who were receiving outpatient care at a hospital or clinic with a diagnosis of either mild to moderate hypertension, mild to moderate alterations in lipid profile or pre-diabetes. To select potential participants from the study population, subjects with a medical history of diabetes, measuring fasting blood glucose, lipid profile and blood pressure were screened.Following screening, participants were divided evenly into three groups: experimental group (1, 2) and one control group. The participants were advised to take 2 slices of bread in breakfast. Individualized plans were given according to their nutrient requirements. A systematic communication plan was developed in order to follow up with participants on their daily consumption of the suggested watermelon rind-based bread through telephonic conversations. For continuous assistance there was a WhatsApp group set up where members may ask issues and get help. The follow up for patients were conducted every month; baseline and after 6 pre-treatments. Appointments for follow-up exams were done after every 15 days in order to track developments, anthropometric measurements were calculated every follow up and modify the dosage as necessary. The baseline and post study test was compared to test the hypothesis.

研究类型

介入性

注册 (实际的)

120

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

    • Punjab Province
      • Lahore、Punjab Province、巴基斯坦
        • University of Lahore

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

  • 成人
  • 年长者

接受健康志愿者

不

描述

Inclusion Criteria:

  • The inclusion criterion was target adults with both gender aged 35-65 years. Adults with a diagnosis of mild to moderate hypertension Mild hypertension (140-159/90-99 mm Hg) Moderate hypertension (160-179/100-109 mm Hg) Adults having mild to moderate alterations in lipid profile Triglycerides: 150 to 499 mg/dL LDL-C levels: Mild Alteration (130 to 159 mg/dL) and Moderate Alteration (160 to 189 mg/dL) Adults with pre-diabetes (hbA1c= 5.6-6.4%)

Exclusion Criteria:

  • Any person allergic to wheat.

    • Any person any person allergic to watermelon rind.
    • Any adult having pancreatitis and hepatitis.
    • Any adults having serious health conditions like cancer.

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:支持治疗
  • 分配:随机化
  • 介入模型:并行分配
  • 屏蔽:无(打开标签)

武器和干预

参与者组/臂
干预/治疗
安慰剂比较:Control group on whole wheat bread
Participants were only subjected to use Wheat bread in breakfast.
Participants were advised to take Two slices of wheat bread in breakfast for the duration of 02 months.
实验性的:G1 on 40% WRB
Participants were advised to take Watermelon rind-based bread (40% ) in breakfast for the duration of 02 months.
Participants were advised to take 2 slices of Watermelon rind-based bread in breakfast for the duration of 02 months.
实验性的:G 2 on 60% WRB
Participants were advised to take Watermelon rind-based bread (60% ) in breakfast for the duration of 02 month.
Group 2: Participants were advised to take 2 slices of Watermelon rind-based bread in breakfast for the duration of 02 months.

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
Anthropometric Measurements
大体时间:60 days
for body mass index weight in kg and height in meters squared, were used to calculate changes in body size.
60 days
Lipid Profile
大体时间:60 days
Blood lipid profile was obtained using fasting blood samples to determine serum total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglycerides were monitored pre and post intervention.
60 days
Blood pressure
大体时间:60 days
Blood pressure was checked using an automated sphygmomanometer. Sitting blood pressure was measured in two ways; systolic blood pressure and diastolic blood pressure after 5 minutes rest. For analysis, the average of the three readings were taken.
60 days

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 首席研究员:Maria Aslam、University of Lahore

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2025年6月12日

初级完成 (实际的)

2025年8月19日

研究完成 (实际的)

2025年9月20日

研究注册日期

首次提交

2026年5月8日

首先提交符合 QC 标准的

2026年5月19日

首次发布 (实际的)

2026年5月27日

研究记录更新

最后更新发布 (实际的)

2026年5月27日

上次提交的符合 QC 标准的更新

2026年5月19日

最后验证

2026年5月1日

更多信息

与本研究相关的术语

其他研究编号

  • IRB-UOL-FAHS/837/2024

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)?

不

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

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