Gen AI Powered Behavioral Support Plus Chewing Gum Intervention for Construction Workers Who Smoke
Build to Quit 「築建無煙」: Gen AI Powered Behavioral Support Plus Chewing Gum Intervention for Construction Workers Who Smoke: A Pragmatic, Pilot, Cluster Randomized Controlled Trial
The goal of this pilot trial is to learn if 1-week NRT sampling, 3-week chewing gum, and 12-week chatbot-delivered instant messaging support works to help smoking cessation in construction workers who smoke. It will also learn about the feasibility, acceptability, and preliminary effectiveness of delivering the comprehensive intervention in construction settings. The main questions it aims to answer are:
- Will the integrated intervention, comprising NRT sampling, chewing gum, and chatbot-delivered instant messaging support, show feasibility, acceptability, and appropriateness for delivery in construction worksite settings?
- Will participants who receive the comprehensive intervention have a higher validated abstinence rate than those who receive NRT sampling alone?
Researchers will compare the integrated intervention, comprising NRT sampling, chewing gum, and chatbot-delivered instant messaging support, to the standard care group (NRT sampling alone) to see if the integrated intervention works to promote smoking cessation.
Participants in the intervention group will receive:
- AWARD advice and brief video
- 1-week NRT sampling
- 3-week chewing gum
- 12-week chatbot-based instant messaging support (via WhatsApp)
研究概览
地位
条件
详细说明
Hong Kong has achieved a sustained reduction in daily cigarette smoking, from 23.3% in the early 1980s to 8.5% in 2025. However, the current prevalence remains above the Government's Towards 2025 target of 7.8%, indicating the need for continued and targeted cessation efforts. The construction industry represents a particularly important setting for intervention, as recent legislative amendments to designate construction sites as no-smoking areas have further strengthened the policy basis for promoting smoke-free worksites.
Construction workers (CWs) are a high-priority population for smoking cessation because they have consistently higher smoking prevalence than many other occupational groups and the general population. In Hong Kong, a workplace health study found that 45% of construction workers were daily smokers, nearly twice the prevalence among office clerks/professionals. For CWs, smoking may compound existing occupational health risks by increasing susceptibility to respiratory and cardiovascular diseases in a physically demanding and dust-exposed work environment.
This study proposes a comprehensive worksite-targeted smoking cessation intervention model for CWs who smoke in Hong Kong, integrating NRT sampling, chewing gum support, and chatbot-delivered instant messaging. NRT is an evidence-based pharmacotherapy for reducing nicotine withdrawal symptoms and supporting smoking abstinence, and has been widely used in community-based cessation interventions. For CWs, short-term NRT sampling may provide immediate access to evidence-based pharmacological support, reduce early withdrawal symptoms, and lower the initial barrier to treatment uptake in a worksite setting. Chewing gum may complement NRT sampling by serving as a low-cost behavioral substitute for smoking, particularly by replacing the hand-to-mouth and oral routines associated with cigarette use. Chatbot-delivered instant messaging support can further extend the intervention beyond the worksite by providing 24/7 support, reminders for NRT and chewing gum use, and real-time assistance during cravings or high-risk smoking situations.
研究类型
注册 (估计的)
阶段
- 不适用
联系人和位置
学习联系方式
- 姓名：Man Ping Wang, PhD
- 电话号码：+852 3917 6636
- 邮箱：mpwang@hku.hk
研究联系人备份
- 姓名：Mengyao Li, Mphil
- 电话号码：+852 6851 8462
- 邮箱：lmy0814@connect.hku.hk
学习地点
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Hong Kong
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Hong Kong、Hong Kong、香港、999077
- Hong Kong Council on Smoking and Health (COSH)
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接触：
- Fung Wong
- 电话号码：+852 2180 5186
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副研究员：
- Tai Hing Lam, MD
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副研究员：
- Tzu Tsun Luk, PhD
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副研究员：
- Xiaoyun Xie, MPH
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副研究员：
- Mengyao Li, Mphil
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副研究员：
- Ziqiu Guo, PhD
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副研究员：
- Yilan Wu, Mphil
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参与标准
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
描述
Inclusion Criteria:
- Hong Kong residents aged 18 or above
- Smoke at least one cigarette per day in the preceding 3-month
- Able to communicate in Cantonese (including reading and writing Chinese)
- Saliva cotinine 30 ng/ml or above
- Intent to quit / reduce smoking
- Have instant messaging tool (WhatsApp) installed
- Able to use instant messaging tool (e.g., WhatsApp) for communication.
Exclusion Criteria:
- Smokers who are participating in other smoking cessation programmes
- Smokers who are using any smoking cessation medication
- Smokers who are presenting with the following oral diseases, including recent oral surgery or tooth extraction, unstable dentures, significant tooth mobility or advanced periodontal disease, temporomandibular pain or dysfunction, or painful oral mucosal lesions
学习计划
研究是如何设计的？
设计细节
- 主要用途：卫生服务研究
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：干预组
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内容包括戒烟的好处、吸烟与疾病、戒烟的方法、戒断症状的处理方法、戒烟声明等。
奖励建议包括询问有关吸烟历史的询问，警告高风险，建议退出，将吸烟者推荐给戒烟服务（带有推荐卡），然后再做一次。
内容包括简短的信息以及现有的戒烟服务，联系方式，动机信息以及强大的支持消息或口号的重点。
The contents of the leaflet include (1) highlights of the absolute risk of death due to smoking; (2) the whole list of diseases caused by active and secondhand smoking; (3) ten horrible pictorial warnings of health consequences of smoking and second-hand smoking in one page to maximize the impacts; (4) benefits of SC and (5) simple messages to encourage participants to quit smoking.
Participants in both group will receive a 1-week supply of free nicotine gum (2 mg or 4 mg).
The dosage of nicotine gum will be guided by participants' daily cigarette consumption, in accordance with recommendations from the Department of Health.
Research assistants will explain the benefits of NRT for smoking cessation, provide instructions on the correct use of nicotine gum, encourage participants to continue using nicotine gum after completing the free sample where appropriate, and advise participants to reduce smoking or make a quit attempt when using NRT.
Participants in the intervention group will receive 6 packs of chewing gum at baseline (2 packs per week).
Chewing gum will be presented as a practical strategy to replace the hand-to-mouth and oral routines associated with smoking, particularly during work breaks, after meals, in other smoking-related situations at construction sites, or when participants are unwilling to use nicotine gum.
Participants in the intervention group will receive 12 weeks of instant messaging support delivered by the LLM-based chatbot accessible via WhatsApp platform.
The chatbot, powered by Claude model (or more advanced model available) using prompt-engineering and agent-based techniques, will deliver theory-based and structured intervention alongside freeform, on-demand support.
The structured intervention session deploys the 5As model (Ask, Advise, Assess, Assist, and Arrange follow-up) and 5Rs model (Relevance, Risks, Rewards, Roadblocks, Repetition), as used in our previous telephone-counselling trials and recommended by WHO for brief SC intervention.
Participants in both groups will receive a brief motivational video (15-second) via WhatsApp.
The video will feature a construction worker who successfully quit smoking in our previous trial, providing a relatable peer role model for participants.
The video will welcome participants to the programme, encourage them to make a quit attempt, and promote early use of nicotine gum as a practical strategy for managing cravings and supporting smoking cessation.
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有源比较器：控制组
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内容包括戒烟的好处、吸烟与疾病、戒烟的方法、戒断症状的处理方法、戒烟声明等。
奖励建议包括询问有关吸烟历史的询问，警告高风险，建议退出，将吸烟者推荐给戒烟服务（带有推荐卡），然后再做一次。
内容包括简短的信息以及现有的戒烟服务，联系方式，动机信息以及强大的支持消息或口号的重点。
The contents of the leaflet include (1) highlights of the absolute risk of death due to smoking; (2) the whole list of diseases caused by active and secondhand smoking; (3) ten horrible pictorial warnings of health consequences of smoking and second-hand smoking in one page to maximize the impacts; (4) benefits of SC and (5) simple messages to encourage participants to quit smoking.
Participants in both group will receive a 1-week supply of free nicotine gum (2 mg or 4 mg).
The dosage of nicotine gum will be guided by participants' daily cigarette consumption, in accordance with recommendations from the Department of Health.
Research assistants will explain the benefits of NRT for smoking cessation, provide instructions on the correct use of nicotine gum, encourage participants to continue using nicotine gum after completing the free sample where appropriate, and advise participants to reduce smoking or make a quit attempt when using NRT.
Participants in both groups will receive a brief motivational video (15-second) via WhatsApp.
The video will feature a construction worker who successfully quit smoking in our previous trial, providing a relatable peer role model for participants.
The video will welcome participants to the programme, encourage them to make a quit attempt, and promote early use of nicotine gum as a practical strategy for managing cravings and supporting smoking cessation.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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经生化验证的禁欲
大体时间：6个月的随访
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定义为呼出的 CO 水平 <4ppm 且唾液可替宁水平≤30 ng/ml
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6个月的随访
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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经生化验证的禁欲
大体时间：3个月的随访
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定义为呼出的 CO 水平 <4ppm 且唾液可替宁水平≤30 ng/ml
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3个月的随访
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自我报告的7天点场禁欲
大体时间：3个月和6个月的随访
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在后续行动之前的7天内没有抽烟的吸烟者
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3个月和6个月的随访
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自我报告的减少
大体时间：1-，2-，3个月和6个月的随访
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根据基线每日香烟的数量至少减少50％定义
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1-，2-，3个月和6个月的随访
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自我报告使用戒烟服务
大体时间：1-，2-，3个月和6个月的随访
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在1个，2、3和6个月的随访中使用戒烟服务。
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1-，2-，3个月和6个月的随访
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Family well-being
大体时间：3- and 6-month follow-ups
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Family well-being will be assessed using the 3H scale, which measures perceived family health, happiness, and harmony on a 0-10 scale.
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3- and 6-month follow-ups
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Perceived family happiness
大体时间：3- and 6-month follow-ups
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Perceived family happiness will be measured using a single-item self-reported family happiness scale ranging from 0 to 10.
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3- and 6-month follow-ups
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其他结果措施
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Recruitment rate
大体时间：Baseline
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Defined as the number of participants divided by the number of eligible smokers
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Baseline
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Retention rate
大体时间：1-, 2-, 3- and 6-month follow-ups
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Defined as the number of participants who completed the follow-up divided by the number of participants
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1-, 2-, 3- and 6-month follow-ups
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Acceptability of NRT sampling
大体时间：1-, 2-, 3- and 6-month follow-ups
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Acceptability of NRT sampling will be assessed through 4 brief items (score range from 0 to10) on perceived usefulness for craving relief, perceived side effects, willingness to continue using NRT after the free sample, and overall satisfaction with the NRT gum.
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1-, 2-, 3- and 6-month follow-ups
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Acceptability of chewing gum
大体时间：1-, 2-, 3- and 6-month follow-ups
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Acceptability of chewing gum will be assessed through 3 brief items (score range from 0 to 10) on perceived usefulness for behavioral substitution, perceived fit with construction worksite routines, and willingness to continue using chewing gum as a cessation aid.
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1-, 2-, 3- and 6-month follow-ups
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Self-reported adverse events
大体时间：1-, 2-, 3- and 6-month follow-ups
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Self-reported adverse events related to nicotine gum and chewing gum will be assessed using a binary question: "Have you experienced any adverse events when using nicotine gum or chewing gum?"
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1-, 2-, 3- and 6-month follow-ups
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Chatbot usability
大体时间：3-month follow-up
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Chatbot usability will be evaluated using the 11-item Bot Usability Scale (BUS), which assesses perceived effectiveness, efficiency, and satisfaction.
The score of the Bot Usability Scale ranges from 0 to 100, with the higher score indicating more usability of the chatbot.
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3-month follow-up
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合作者和调查者
调查人员
- 首席研究员：Man Ping Wang, PhD、The University of Hong Kong
研究记录日期
研究主要日期
学习开始 (估计的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他相关的 MeSH 术语
其他研究编号
- Build to Quit
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
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