Collection of Biological Samples From Patients With Echinococcosis and Implementation of a Home-made PCR Method (Echino_home)
Pilot Observational Study Involving the Collection of Biological Samples and Clinical Data From Patients With Echinococcosis: Implementation and Evaluation of a Home-made PCR Method
研究概览
地位
条件
详细说明
Echinococcosis is a parasitic zoonotic disease caused by Echinococcus species. Current diagnosis mainly relies on imaging, serology and microscopy. However, microscopy may have limited sensitivity and cannot reliably distinguish between species.
The primary aim of this study is to collect biological samples and develop an in-house PCR diagnostic protocol.
The PCR will detect parasitic genetic material and differentiate among four Echinococcus species, and the molecular results will be compared with conventional serology and microscopy. Whole-genome sequencing will also be used for species characterisation.
In synthesis, the study aims to improve molecular diagnosis and knowledge of pulmonary echinococcosis.
研究类型
注册 (估计的)
联系人和位置
学习联系方式
- 姓名：Clinical Trial Center
- 电话号码：+39 0131206893
- 邮箱：clinicaltrialcenter@ospedale.al.it
学习地点
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Piemonte, Italy
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Alessandria、Piemonte, Italy、意大利、15121
- 招聘中
- SC Chirurgia Toracica
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接触：
- SC Chirurgia Toracica
- 电话号码：+39 0131206621
- 邮箱：SMeda@ospedale.al.it
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参与标准
资格标准
适合学习的年龄
- 孩子
- 成人
- 年长者
接受健康志愿者
取样方法
研究人群
描述
Inclusion Criteria:
- Suspected diagnosis of echinococcosis
- Patients requiring surgery to remove cysts
- Patients aged 6 years or over
- Signature of informed consent
Exclusion Criteria:
- Patients who are candidates for surgery for other reasons
学习计划
研究是如何设计的？
设计细节
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Development of a homemade PCR protocol for diagnostic use
大体时间：Through study completion, expected to last 20 years
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Development of a homemade PCR protocol for diagnostic use, aimed at detecting genetic material of parasitic origin in lesions or biopsy specimens caused by Echinococcus spp.
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Through study completion, expected to last 20 years
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Costs associated to hospitalization
大体时间：Through study completion, expected to last 20 years
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Analysis of the costs associated to hospitalization
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Through study completion, expected to last 20 years
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合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.