AOSLO Imaging for the Study of Cellular Alterations in Retinal Neurodegeneration (RETION)

Inclusion Criteria:

Patients:

• 100 subjects aged 10 to 79 years with a condition that may affect the inner retina (e.g., glaucoma, optic neuropathy, etc.)
• 100 subjects aged 10 to 80 years with a condition that may affect the outer retina (e.g., AMD, retinitis pigmentosa, etc.)
• Male or female
• Covered by health insurance

Healthy volunteers:

• 30 subjects aged over 50 and under 80
• 30 subjects aged over 18 and under 50
• Male or female
• Healthy subjects with no known condition that directly or indirectly affects the structure of the eye
• Covered by health insurance

Exclusion Criteria:

For all subjects:

• Inability to remain motionless on a standard ophthalmic chin rest. RETION_Protocol_v2.0 dated June 10, 2026_IDRCB: 2026-A00324-47 Page 10 of 44
• Subjects taking medications or suffering from a medical condition that could interfere with the evaluations planned under the protocol;
• Participants allergic to tropicamide in cases where pupil dilation is required. ☞ Wearing glasses or contact lenses to correct a refractive error is not considered an exclusion criterion.