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Effects of Instrument-Assisted Soft Tissue Mobilization (IASTM) Along With Conventional Physical Therapy on Upper Limb Function, Strength, Range of Motion, and Spasticity in Patients With Subacute Stroke.

2026年11月8日 更新者:Ibadat International University, Islamabad

This randomized controlled trial aims to compare the effects of IASTM (Instrument-Assisted Soft Tissue Mobilization) along with conventional physical therapy on function, strength, range of motion, and spasticity of the upper limb in patients with subacute stroke.

研究概览

研究类型

介入性

注册 (估计的)

46

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习联系方式

研究联系人备份

  • 姓名:Nazish Rafique Dr Nazish Rafique, DPT, MS-PT NMPT
  • 电话号码:03002132436
  • 邮箱:nazish2312@gmail.com

学习地点

    • Balochistan
      • Quetta、Balochistan、巴基斯坦
        • 招聘中
        • Barkat Medical and Physical-Therapy Center Hazaratown Quetta
        • 接触:

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

40年 至 60年 (成人)

接受健康志愿者

不

有资格学习的性别

全部

描述

Inclusion Criteria:

  • First-ever stroke (ischemic or hemorrhagic) diagnosed via CT/MRI
  • Subacute stage (2 weeks to 6 months post-stroke)
  • Age 40-60 years
  • Upper limb hemiparesis with Modified Ashworth Scale score 2 and 3
  • MMSE (Mini-Mental State Examination) score ≥ 24
  • Capable of follow simple verbal commands

Exclusion Criteria:

  • Severe cognitive impairment affecting the ability to follow instructions.
  • Recurrent stroke
  • Presence of other neurological disorders such as Parkinson's disease or multiple sclerosis etc.
  • Recent upper limb surgery, fractures or musculoskeletal injury affecting the arm or hand.
  • Fixed contracture of upper limb joints
  • Severe aphasia or inability to follow commands
  • Uncontrolled diabetes mellitus, hypertension
  • Serious cardiac problems or unstable cardiovascular disease
  • Skin conditions, open wounds, or infections affecting upper limb

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:治疗
  • 分配:随机化
  • 介入模型:并行分配
  • 屏蔽:单身的

武器和干预

参与者组/臂
干预/治疗
实验性的:Group A: IASTM + Conventional Physical Therapy

IASTM + Conventional Physical Therapy

5-10 minutes per session applied to affected upper limb muscles (biceps brachii, brachialis, flexor carpi radialis, flexor carpi ulnaris, thenar and hypothenar muscles) using stainless steel instruments

  • Technique: Multidirectional strokes at 30-60 second intervals
  • Intensity: Moderate pressure causing mild erythema without bruising
  • Frequency: 3 sessions/week for 6 weeks
  • Conservative Physical Therapy: 45-minute session including
  • Passive stretching of spastic muscles (15 min)
  • Active-assisted ROM exercises (10 min)
  • Strengthening exercises (10 min) - including isometric holds, concentric/eccentric contractions as tolerated
  • Task-oriented Training of upper limb, {Reaching activities, Grasping & releasing objects, Object manipulation tasks (stacking blocks, turning objects), Simulated ADL tasks (feeding, grooming) (10 min)}
有源比较器:Group B: Conventional Physical Therapy

Conventional Physical Therapy

45-minute session.

  • Passive stretching of spastic muscles (15 min)
  • Active-assisted ROM exercises (10 min)
  • Strengthening exercises (10 min)-including isometric holds and concentric/eccentric contractions as tolerated
  • Task-oriented Training of upper limb, {Reaching activities, Grasping & releasing objects, Object manipulation tasks (stacking blocks, turning objects), Simulated ADL tasks (feeding, grooming)} (10 min)

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
Modified Ashworth Scale (MAS)
大体时间:Baseline, 3rd week, 6th week

Moderate-good reliability (κ = 0.65-0.78). The modified Ashworth scale will be used to determine the level of spasticity in the participants. The assessment is done by bringing the patient's limb to the possible maximal extension from flexion and then flexion to extension until the point of resistance is met. Scoring is done from 0-4 (0 being normal while 4 being rigid).

Baseline, 3rd week, 6th week
Fugl-Meyer Assessment Upper Extremity (FMA-UE)
大体时间:Baseline, 3rd week, 6th week

It is a stroke-specific, performance-based outcome measure used to assess upper limb motor recovery following a stroke. The FMA-UE consists of 33 items evaluating reflex activity, voluntary movement within and out of synergy, wrist and hand function, and coordination/speed. Each item is scored on a 3-point ordinal scale (0 = cannot perform, 1 = performs partially, 2 = performs fully), with a maximum score of 66 indicating optimal motor function.

Baseline, 3rd week, 6th week
Muscle Strength Manual Muscle Testing (MMT)
大体时间:Baseline, 3rd week, 6th week

A standardized, performance-based outcome measure assessing muscle strength on a 6-point ordinal scale (0 = no contraction to 5 = normal strength). Evaluates key upper limb muscle groups, including shoulder, elbow, forearm, wrist, and grip bilaterally. Requires no equipment, is clinically feasible, and provides immediate interpretable results. Excellent reliability (ICC = 0.84-0.92) in stroke.

Baseline, 3rd week, 6th week
Goniometry
大体时间:Baseline, 3rd week, 6th week

Good-excellent reliability (ICC = 0.90-0.98). A goniometer will be used to assess the range of motion of all joints. A goniometer can assess both active and passive ROM.

Baseline, 3rd week, 6th week

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 学习椅:Nazish Rafique, DPT, MS-PT NMPT、Ibadat International University

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

一般刊物

  • Shahid J, Kashif A, Shahid MK. A comprehensive review of physical therapy interventions for stroke rehabilitation: impairment-based approaches and functional goals. Brain Sciences. 2023;13(5):717. Sherin A, Ul-Haq Z, Fazid S, Shah BH, Khattak MI, Nabi F. Prevalence of stroke in Pakistan: Findings from Khyber Pakhtunkhwa integrated population health survey (KP-IPHS) 2016-17. Pakistan Journal of Medical Sciences. 2020;36(7):1435. Baker, R. T., Nasypany, A., Seegmiller, J. G., & Baker, J. G. (2023). Instrument-assisted soft tissue mobilization: A systematic review and meta-analysis of current literature. Journal of Athletic Training, 58(2), 112-125. Cheatham, S. W., Baker, R. T., & Abdenour, T. E. (2021). Instrument-assisted soft tissue mobilization: A clinical commentary. International Journal of Athletic Therapy and Training, 26(4), 187-193. Cuesta-Vargas, A. I., González-Sánchez, M., & Kuisma, R. (2022). Reliability of goniometric measurements in stroke patients: A systematic review. Disability and Rehabilitation, 44(8), 1342-1352. Grefkes, C., & Fink, G. R. (2020). Recovery from stroke: Current concepts and future perspectives. Neurological Research and Practice, 2(1), 17-29. Harb, A., & Kishner, S. (2023). Modified Ashworth Scale. In StatPearls. StatPearls Publishing.

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2026年7月9日

初级完成 (估计的)

2026年11月15日

研究完成 (估计的)

2026年11月30日

研究注册日期

首次提交

2026年11月8日

首先提交符合 QC 标准的

2026年11月8日

首次发布 (实际的)

2026年11月13日

研究记录更新

最后更新发布 (实际的)

2026年11月13日

上次提交的符合 QC 标准的更新

2026年11月8日

最后验证

2026年11月1日

更多信息

与本研究相关的术语

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)?

不

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

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