- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00059449
Role of Epidermal Growth Factor (EGF) in Development of Necrotizing Enterocolitis
January 12, 2010 updated by: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Necrotizing enterocolitis (NEC) is a serious gastrointestinal disorder that primarily affects preterm infants.
About 10% of babies less than 32 weeks gestation at birth will develop it.
Overall, 30% of babies who develop NEC will die from it, with many others developing long term gastrointestinal problems.
The most important factor in its development is a premature intestinal tract.
Epidermal growth factor (EGF) is an important growth factor in the development and maintenance of the gastrointestinal tract.
This study will look for a relationship between EGF levels in premature babies and the development of NEC.
Study Overview
Status
Completed
Conditions
Study Type
Observational
Enrollment (Anticipated)
372
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Ohio
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Cincinnati, Ohio, United States, 45229
- Cincinnati Children's Hospital Medical Center
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Cincinnati, Ohio, United States, 45220
- Good Samaritan Hospital
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Cincinnati, Ohio, United States, 45229
- University Hospital
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
No older than 3 days (Child)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Gestational Age greater than 23 weeks at birth
- Birth weight greater than 500 grams
- Age less than 72 hours of life
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Time Perspectives: Prospective
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Registration Dates
First Submitted
April 25, 2003
First Submitted That Met QC Criteria
April 28, 2003
First Posted (Estimate)
April 29, 2003
Study Record Updates
Last Update Posted (Estimate)
January 13, 2010
Last Update Submitted That Met QC Criteria
January 12, 2010
Last Verified
January 1, 2010
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- EGFDNE (completed)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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