Cardiology Biobank Registry

In the present study, investigators intend to establish a large database of cardiovascular patients. More specifically, investigators will create a database of approximately 12,000 cardiac catheterization and heart failure patients from Emory University Hospital, the Emory Clinic, Emory University Hospital Midtown, Grady Memorial Hospital, Atlanta VA Medical Center, Organized/Planned Community Events in the Atlanta Metropolitan area, held at places of Worship, local Community Centers, shopping Malls, doctor's Offices and Health Clinics and any other miscellaneous locations, e.g. Parks, Leisure centers, Conference centers.

Once the data has been collected, investigators will run a variety of statistical analyses to which will help us to learn more about the factors that cause various cardiovascular diseases such as coronary heart disease, angina, heart failure, hypertension, and stroke. The statistical analyses will also help us to understand how these diseases can be treated more effectively.

By collecting a large amount of data on a large number of cardiovascular patients, investigators will be able to analyze, with a great deal of precision, those factors that influence the onset, course, and treatment of cardiovascular disease. The results of these precise analyses can then be used to help optimize clinical efforts to prevent and treat cardiovascular disease.

Study Overview

• Status: Recruiting
• Conditions: Cardiovascular Disease

Detailed Description

Over the last several decades, scientists have made great progress in their understanding of cardiovascular disease. Nevertheless, much remains to be learned about the causes, course, and treatment of cardiovascular disease. In order to learn more about this topic, it is important to establish large databases of cardiovascular patients. These databases allows scientists to investigate, in a rigorous and precise manner, those factors that influence cardiovascular disease.

In the present study, investigators intend to establish a large database of cardiovascular patients. More specifically, investigators will create a database of approximately 12,000 cardiac catheterization and heart failure patients from Emory University Hospital, the Emory Clinic, Emory University Hospital Midtown, Grady Memorial Hospital, Atlanta VA Medical Center, Organized/Planned Community Events in the Atlanta Metropolitan area, held at places of Worship, local Community Centers, shopping Malls, doctor's Offices and Health Clinics and any other miscellaneous locations, e.g. Parks, Leisure centers, Conference centers.

Investigators will collect a large amount of data on these patients. Data to be collected will include information on:

Medical record data, including imaging Patient questionnaire data DNA and other biochemical data obtained and/or generated from patient blood samples or cheek (buccal) swabs Non-invasive measurements of blood pressure, heart rate and studies relating to assessment of the health of arteries

The data noted above will be collected by:

administering questionnaires/interviews to the patients accessing the medical records of the patients collecting blood samples from patients which will be analyzed by laboratories for their biochemical content.

Once the data has been collected, investigators will run a variety of statistical analyses to which will help us to learn more about the factors that cause various cardiovascular diseases such as coronary heart disease, angina, heart failure, hypertension, and stroke. The statistical analyses will also help investigators to understand how these diseases can be treated more effectively.

How the Research Will Advance Scientific Knowledge/Human Health:

By collecting a large amount of data on a large number of cardiovascular patients, investigators will be able to analyze, with a great deal of precision, those factors that influence the onset, course, and treatment of cardiovascular disease. The results of these precise analyses can then be used to help optimize clinical efforts to prevent and treat cardiovascular disease.

• Study Type: Observational
• Enrollment (Estimated): 12000

Contacts and Locations

• Study Contact: Name: Ayman J Tahhan, MD; Phone Number: 404 712 0168; Email: ayman.tahhan@emory.edu
• Study Contact Backup: Name: Salman Sher, MD; Phone Number: 404 412 0170; Email: ssher2@emory.edu

Study Locations

• United States
  • Georgia
    • Atlanta, Georgia, United States, 30322
      • Recruiting
      • Emory School Of Medicine
      • Contact: Ayman J Tahhan, MD; Phone Number: 404 712 0168; Email: ayman.tahhan@emory.edu
      • Contact: Salman Sher, MD; Phone Number: 404 712 0170; Email: ssher2@emory.edu
      • Principal Investigator: Arshed A Quyyumi, MD

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 20 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

General population & patients presenting to the hospital

Description

Inclusion Criteria:

1. All hospital and clinic participants aged 18 years and older

2. Participants with and without active or presumed cardiovascular disease including but not limited to:

   1. Coronary Artery Disease
   2. Heart Failure and Cardiomyopathies
   3. Peripheral Vascular Disease
   4. Valve disease
   5. Adult Congenital Heart disease
   6. Electrophysiological Disorders
3. Any individual aged 18 and above in satisfactory physical health and able to tolerate a blood draw or buccal swab.

Exclusion Criteria:

1. Significant Documented Anemia (Hemoglobin <8 g/dL)
2. Blood transfusions within past 3 weeks
3. Enrollment against doctor recommendation

4. Participant not able to provide consent including but not limited to:

   1. Intubated and critically unwell participants
   2. Dementia
   3. Alzheimer's disease
   4. Moderate to severe alcohol or drug abuse
   5. Against religious beliefs (e.g. Jehovah's witness)

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
All cause death	Continuous

Secondary Outcome Measures

Outcome Measure	Time Frame
Cardiovascular death	Continuous
Re-hospitalization for heart failure	Continuous

Other Outcome Measures

Outcome Measure	Time Frame
Myocardial Infarction	Continuous
Stroke	Continuous

Collaborators and Investigators

• Sponsor: Emory University
• Investigators: Principal Investigator: Arshed A Quyyumi, MD, Emory School Of Medicine

Study record dates

Study Major Dates

• Study Start: December 1, 2003
• Primary Completion (Estimated): April 1, 2030
• Study Completion (Estimated): April 1, 2030

Study Registration Dates

• First Submitted: September 19, 2006
• First Submitted That Met QC Criteria: September 20, 2006
• First Posted (Estimated): September 21, 2006

Study Record Updates

• Last Update Posted (Actual): June 29, 2026
• Last Update Submitted That Met QC Criteria: June 24, 2026
• Last Verified: June 1, 2026

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Cardiovascular Diseases
• Other Study ID Numbers: IRB00000343; 950-2003 (Other Identifier: Other); 2025P011265 (Other Identifier: Emory IRB)

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No