- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00657436
Myeloid-Related Protein in Evaluation of Acute Chest Pain in the Emergency Departement (MyRiAD)
Study of Myeloid-related Protein 8/14 and Additional Biomarkers (Multi Marker Approach) for Early Diagnosis and Risk Stratification in Patients Presenting With Acute Chest Pain at the Emergency Department
The purpose of the study is the evaluation of multiple biomarkers related to acute coronary syndromes, including myeloid-related protein 8/14 (MRP 8/14), along with established clinical markers, for early diagnosis and risk stratification in patients presenting with acute chest pain at the emergency department.
Study hypothesis: MRP 8/14, alone or together with other established or new biomarkers, increases the earliness, sensitivity, and specificity of diagnosing acute coronary syndromes.
Study Overview
Status
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
-
-
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Zurich, Switzerland, 8091
- Cardiology, University Hospital
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-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- All patients in the emergency department of the University Hospital Zurich with measurement of troponin during the routine diagnostic evaluation.
Exclusion Criteria:
- Refusal or inability to give informed consent.
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Diagnosis of acute coronary syndrome
Time Frame: Emergency room and/or hospital stay
|
Emergency room and/or hospital stay
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Mortality
Time Frame: 1 year
|
1 year
|
Incidence of any acute coronary event
Time Frame: 1 year
|
1 year
|
Morbidity from coronary artery disease
Time Frame: 1 year
|
1 year
|
Collaborators and Investigators
Sponsor
Collaborators
Investigators
- Principal Investigator: Willibald Maier, MD, Cardiology, University Hospital Zurich
Publications and helpful links
Study record dates
Study Major Dates
Study Start
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
- Ischemia
- Pathologic Processes
- Necrosis
- Heart Diseases
- Cardiovascular Diseases
- Vascular Diseases
- Pain
- Neurologic Manifestations
- Embolism and Thrombosis
- Coronary Disease
- Myocardial Infarction
- Infarction
- Myocardial Ischemia
- Chest Pain
- Thrombosis
- Acute Coronary Syndrome
- Coronary Occlusion
- Coronary Thrombosis
Other Study ID Numbers
- MyRiAD
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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