- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00810550
Carotid Ultrasound in the Evaluation of Heart Failure (CUE-HF)
April 5, 2016 updated by: Harmony R. Reynolds, NYU Langone Health
Coronary artery disease (CAD, cholesterol plaque buildup in the heart arteries) is the most common cause of left ventricular systolic dysfunction (weakening of the heart muscle).
The standard test to find coronary artery disease is coronary angiography.
This test is highly accurate but is invasive and carries a small risk of complications.
This study investigates ultrasound of the carotid (neck) arteries as a screening test for severe coronary artery disease as a cause of left ventricular systolic dysfunction.
It is hypothesized that carotid ultrasound will have excellent negative predictive value for severe CAD.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
Coronary artery disease (CAD, cholesterol plaque buildup in the heart arteries) is the most common cause of left ventricular systolic dysfunction (weakening of the heart muscle).
The standard test to find coronary artery disease is coronary angiography.
This test is highly accurate but is invasive and carries a small risk of complications.
This study investigates ultrasound of the carotid (neck) arteries as a screening test for severe coronary artery disease as a cause of left ventricular systolic dysfunction.
It is hypothesized that carotid ultrasound will have excellent negative predictive value for severe CAD.
Study Type
Interventional
Enrollment (Actual)
150
Phase
- Not Applicable
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 99 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- LVEF 40% or less
Exclusion Criteria:
- Prior diagnosis of coronary or carotid obstructive atherosclerosis
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Diagnostic
- Allocation: N/A
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Other: LV systolic dysfunction
Diagnostic Testing
|
Measurement of intima-media thickness
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Diagnostic accuracy for severe CAD
Time Frame: 1 Day
|
1 Day
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Diagnostic accuracy for significant CAD
Time Frame: 1 Day
|
1 Day
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
October 1, 2005
Primary Completion (Actual)
December 1, 2008
Study Completion (Actual)
December 1, 2008
Study Registration Dates
First Submitted
December 17, 2008
First Submitted That Met QC Criteria
December 17, 2008
First Posted (Estimate)
December 18, 2008
Study Record Updates
Last Update Posted (Estimate)
April 6, 2016
Last Update Submitted That Met QC Criteria
April 5, 2016
Last Verified
April 1, 2016
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- NYCC CUE-HF
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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Clinical Trials on Carotid ultrasound
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M.D. Anderson Cancer CenterTerminated
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University Hospital, Basel, SwitzerlandSwiss National Science FoundationRecruitingCarotid StenosisSwitzerland
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St. Boniface HospitalWithdrawn