Frequency of Aerobic/Resistance Training in Older Women (SWEET)

October 26, 2015 updated by: University of Alabama at Birmingham
The objective of this study is to provide insight into the effects combined training frequency has on improving fitness, ease of physical activity, and maintenance of a high total energy expenditure. Such information is critical to our understanding of ways to improve well-being, quality of life, and independence of an aging population. 105 participants will be enrolled in this study. The length of time for your involvement in the study will be 32 weeks. You will undergo the procedures listed in this consent form on 3 separate occasions-initially at your entry, at 16 weeks and again at 32 weeks.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Frequency of aerobic/resistance training in older women

Abstract Combined aerobic and resistance training have unique benefits for maintaining a physical activity (PA). However, the optimal training program for combining these two modes of training in older adults is unknown. This study builds on current and past studies showing that training induced gains in aerobic fitness, muscle strength, and ease of PA are important for maintaining an active lifestyle, a favorable body composition, and high bone density. Traditionally 3 d/wk combined training has been felt to be optimal while recent studies suggest 1 d/wk combined training may create similar adaptations as more frequent training. However, our previous and ongoing studies suggest that 1 d/wk combined aerobic and resistance training (C1) may be insufficient stimulus to induce optimal adaptations and that 3 d/wk combined training (C3) may be too frequent a stimulus for older adults. This study will enable us to compare the effects of C1, 2 d/wk combined training (C2), and C3 on fitness, body composition, ease of PA, PA, and total free-living energy expenditure (TEE). We hypothesize that C2 will result in a larger increase in muscle size, bone density, strength, aerobic capacity, power, ease of PA, PA, and TEE than either C1 or C3. Circulating cytokines and psychological mood states linked to chronic overstress will also be examined. Objectives: We will examine changes in circulating cytokines, mood states, muscle size, bone density, aerobic capacity, strength, power, ease of PA, PA, and TEE following 16 and 32 wks training. Design: We will to evaluate 78 (>60 yrs) Black and White women matched for age, race, and BMI into C1, C2, or C3 groups prior to, after 16, and after 32 wks training. Women will undergo evaluation of metabolic parameters in a General Clinical Research Center. Significance: This study should provide insight into the effects combined training frequency has on improving fitness, ease of PA, and maintenance of a high TEE. Such information is critical to our understanding of ways to improve well being, quality of life, and independence of an aging population.

Study Type

Interventional

Enrollment (Actual)

105

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Alabama
      • Birmingham, Alabama, United States, 35294
        • UAB

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

60 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

Female

Description

Inclusion Criteria:,

  • healthy women over 60 years of age,
  • Caucasian or African-American.

Exclusion Criteria:

  • smoking,
  • diabetes,
  • osteoporosis,
  • inability to coperform weight bearing exercises, currently performing to much exercise.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Group 1
1 aerobic and 1 resistance training per week
Other: Frequency of Aerobic/Resistance Training - 3 to 3
comparing group results based upon frequency of exercise
Other Names:
  • freqency of aerobic and resistance training
Active Comparator: Group 2
2 aerobic and 2 resistance training each per week
Other: Frequency of Aerobic/Resistance Training - 3 to 3
comparing group results based upon frequency of exercise
Other Names:
  • freqency of aerobic and resistance training
Active Comparator: Group 3
3 aerobic and 3 resistance training per week
Other: Frequency of Aerobic/Resistance Training - 3 to 3
comparing group results based upon frequency of exercise
Other Names:
  • freqency of aerobic and resistance training

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Use a repeated measures analysis to compare differences in TEE and other parameters among the 3 intervention groups across time
Time Frame: over 32 weeks of training
over 32 weeks of training

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Alabama at Birmingham

Collaborators

National Institute on Aging (NIA)

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2004

Primary Completion (Actual)

March 1, 2011

Study Completion (Actual)

March 1, 2011

Study Registration Dates

First Submitted

December 10, 2009

First Submitted That Met QC Criteria

December 11, 2009

First Posted (Estimate)

December 14, 2009

Study Record Updates

Last Update Posted (Estimate)

October 27, 2015

Last Update Submitted That Met QC Criteria

October 26, 2015

Last Verified

October 1, 2015

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • F050820002
  • R01AG027084 (U.S. NIH Grant/Contract)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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