Seasonal Variation of Ambulatory Blood Pressure

Seasonal Variation of 24hour Ambulatory Blood Pressure Monitoring in Treated Hypertensives

This is a prospective study to evaluate the change in 24 hour ambulatory blood pressure during winter and summer in well controlled treated hypertensives.

Study Overview

• Status: Completed
• Conditions: Hypertension

Detailed Description

Two 24hour ambulatory blood pressure monitorings, 4 to 6 months apart, will be performed on hypertensive subjects on a stable antihypertensive drug therapy for at least 4 weeks.

The correlation of weather and temperature with the 24hour ambulatory blood pressure monitoring will be explored.

• Study Type: Observational
• Enrollment (Actual): 80

Contacts and Locations

Study Locations

• Greece
  • Athens, Greece
    • Hypertension Center, Third Department of Medicine, University of Athens, Greece

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 36 years to 76 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

TREATED HYPERTENSIVES REFERRED TO AN OUTPATIENT CLINIC

Description

Inclusion Criteria:

• Age > 40 yrs
• Treated hypertension on stable treatment for at least 8 weeks
• Average home blood pressure (at least 5 days, 20 readings) < 130/80 mmHg

Exclusion Criteria:

• Congestive heart failure
• Use of loop diuretics

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Only
• Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Mean Difference of Systolic Daytime Ambulatory Blood Pressure Between Summer and Winter.	Mean difference of systolic daytime ambulatory blood pressure measurement during summer and winter period	1 year
Mean Difference of Diastolic Daytime Ambulatory Blood Pressure Between Summer and Winter	Mean Difference of Diastolic Daytime Ambulatory Blood Pressure Measurement During Summer and Winter Period	1 year
Mean Difference of Systolic Night-time Ambulatory Blood Pressure Between Summer and Winter	Mean difference of systolic night-time ambulatory blood pressure measurement during summer and winter period	1 year
Mean Difference of Diastolic Night-time Ambulatory Blood Pressure Between Summer and Winter		1 year

Secondary Outcome Measures

Outcome Measure	Time Frame
Mean Difference of Systolic Clinic Blood Pressure Between Summer and Winter	1 year
Mean Difference of Diastolic Clinic Blood Pressure Between Summer and Winter	1 year
Mean Difference of Systolic Home Blood Pressure Between Summer and Winter	1 year
Mean Difference of Diastolic Home Blood Pressure Between Summer and Winter	1 year

Collaborators and Investigators

• Sponsor: University of Athens
• Investigators: Study Chair: George S Stergiou, MD, Hypertension Center,Third Department of Medicine,University of Athens,Greece

Study record dates

Study Major Dates

• Study Start: January 1, 2010
• Primary Completion (Actual): August 1, 2011
• Study Completion (Actual): August 1, 2011

Study Registration Dates

• First Submitted: April 21, 2010
• First Submitted That Met QC Criteria: May 6, 2010
• First Posted (Estimate): May 10, 2010

Study Record Updates

• Last Update Posted (Estimate): January 23, 2012
• Last Update Submitted That Met QC Criteria: December 8, 2011
• Last Verified: December 1, 2011

More Information

Terms related to this study

• Keywords: TREATMENT OF HYPERTENSION
• Additional Relevant MeSH Terms: Cardiovascular Diseases; Vascular Diseases; Hypertension
• Other Study ID Numbers: SV