Search clinical trials for: Avatrombopag

Total 50 results

Eisai Inc.

Completed

Phase 2, Parallel Group, Rollover Study of AKR-501 in Patients With ChronicITP Who Completed 28 Days of Study Treatment in Protocol 501-CL-003

Idiopathic Thrombocytopenic Purpura

United States
Institute of Hematology & Blood Diseases Hospital...
Fosun Pharmaceutical Distribution Jiangsu co., Limited

Not yet recruiting

Efficacy and Safety of Avatrombopag vs. Avatrombopag Combined With rhTPO in the Treatment of SAA

Anemia, Aplastic
Institute of Hematology & Blood Diseases Hospital...
Henan Cancer Hospital; Tianjin Medical University Second Hospital; The Second... and other collaborators

Recruiting

Avatrombopag in the Treatment of Pediatric Immune Thrombocytopenia

Immune Thrombocytopenia | Treatment

China
Peking Union Medical College Hospital

Recruiting

Efficacy and Safety of Avatrombopag in Cancer Patients With Thrombocytopenia

Thrombocytopenia | Avatrombopag

China
Anhui Provincial Hospital

Recruiting

Avatrombopag for Platelet Recovery Post-UCBT in Patients With Bone Marrow Failure Disease (AVA)

Platelet Recovery After Umbilical Cord Blood Transplantation

China
Eisai Inc.

Completed

A Five-Treatment-Period Study to Evaluate the Single-Dose Pharmacokinetics and Pharmacodynamics of Avatrombopag in Healthy Japanese and White Subjects

Thrombocytopenia

United States
Swedish Orphan Biovitrum

Active, not recruiting

An Observational, Multicenter Study to Evaluate the Use and Effectiveness of Doptelet® in Patients With ITP (ADOPT)

Immune Thrombocytopenia | ITP

Croatia, Czechia, Germany, Italy, Netherlands, Norway, Spain, Switzerland, United Kingdom
Shanghai Zhongshan Hospital

Recruiting

Treatment of Avatrombopag for Thrombocytopenia in Patients Undergoing Selective Resection of Hepatocellular Carcinoma

Thrombocytopenia

China
Anhui Provincial Cancer Hospital

Completed

Avatrombopag on the Treatment of Thrombocytopenia Induced by Chemotherapy of Malignant Tumors

Thrombocytopenia

China
Sobi, Inc.

Active, not recruiting

Evaluation of Avatrombopag for the Treatment of Thrombocytopenia in Japanese Adults With Chronic ITP

Immune Thrombocytopenia

Japan
Sobi, Inc.

Terminated

Avatrombopag for the Treatment of Thrombocytopenia in Adults Scheduled for a Surgical Procedure

Thrombocytopenia

United States
Institute of Hematology & Blood Diseases Hospital
Peking University People's Hospital; Xiyuan Hospital of China Academy of Chinese... and other collaborators

Recruiting

The Safety and Efficacy Study of Avatrombopag Switch in TPO-RA Refractory AA

Refractory Aplastic Anemia

China
Shandong University

Recruiting

Avatrombopag in the Treatment of Primary Immune Thrombocytopenia(ITP)

Primary Immune Thrombocytopenia

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

Avatrombopag Combined With IST as First-line Treatment for SAA

Severe Aplastic Anemia

China
Peking Union Medical College Hospital

Not yet recruiting

Avatrombopag Usage in NSAA

Drug Effect | Aplastic Anemia

China
Sobi, Inc.

Active, not recruiting

Avatrombopag for the Treatment of Thrombocytopenia in Pediatric Subjects With Immune Thrombocytopenia for ≥6 Months

Immune Thrombocytopenia

United States, France, Germany, Hungary, Poland, Russian Federation, Turkey, Ukraine, United Kingdom
Sobi, Inc.

Terminated

Avatrombopag for the Treatment of Thrombocytopenia in Adults With Chronic Liver Disease Undergoing a Procedure

Thrombocytopenia

United States
Sobi, Inc.

Completed

Safety and Treatment Satisfaction in Adults With Chronic ITP After Switching to Avatrombopag From Eltrombopag or Romiplostim

Immune Thrombocytopenia

United States
Sobi, Inc.

Completed

Avatrombopag for the Treatment of Chemotherapy-Induced Thrombocytopenia in Adults With Active Non-Hematological Cancers

Chemotherapy-induced Thrombocytopenia

United States, China, Hungary, Poland, Russian Federation, Serbia, Ukraine
Eisai Inc.

Completed

Study of AKR-501 Tablets Taken Orally Once Daily for 28 Days in Patients With Chronic Idiopathic Thrombocytopenic Purpura (ITP)

Chronic Idiopathic Thrombocytopenic Purpura | Purpura, Thrombocytopenic, Idiopathic

United States
The First Affiliated Hospital of Soochow University

Recruiting

Avatrombopag to Promote Platelet Engraftment After Allo-HSCT

Platelet Disorder

China
Hanny Al-Samkari, MD
Swedish Orphan Biovitrum

Recruiting

Avatrombopag vs. Placebo for CIT in GI Malignancies (ACT-GI)

Gastrointestinal Neoplasms | Gastrointestinal Cancer | Chemotherapy-Induced Thrombocytopenia

United States
Peking University People's Hospital
The First Affiliated Hospital of Nanchang University; Xiangya Hospital of Central... and other collaborators

Not yet recruiting

Efficacy and Safety of Avatrombopag in the Treatment of Thrombocytopenia After Haplo-HSCT (Haplo-HSCT)

Thrombocytopenia | Stem Cell Transplant Complications

China
Second Affiliated Hospital of Guangzhou Medical...

Recruiting

Avatrombopag for HCC Patients With Thrombocytopenia Who Intend to Undergo TACE and/or HAIC

Hepatocellular Carcinoma | Thrombocytopenia

China
Sun Yat-sen University

Not yet recruiting

Avatrombopag for the Primary Prevention of Thrombocytopenia Induced by Cytarabine-based Chemotherapy in Patients With Lymphoma

Lymphoma | Thrombocytopenia | Cytarabine Causing Adverse Effects in Therapeutic Use

China
University of Rochester

Recruiting

Study of Avatrombopag for Temozolomide-induced Thrombocytopenia in Glioma (APATIT-G)

Thrombocytopenia

United States
Eisai Co., Ltd.

Completed

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Once-daily Oral Avatrombopag in Japanese Subjects With Chronic Liver Diseases and Thrombocytopenia

Thrombocytopenia Associated With Chronic Liver Disease

Japan
Eisai Inc.

Completed

Once-Daily Oral Avatrombopag Tablets Used in Subjects With Chronic Liver Diseases and Thrombocytopenia Prior to Elective Surgical or Diagnostic Procedures

Thrombocytopenia Related to Chronic Liver Disease

United States
Ayman Saad
Sobi, Inc.

Withdrawn

Avatrombopag for the Treatment of Thrombocytopenia After Donor Hematopoietic Stem Cell Transplant

Platelet Disorder
Eisai Inc.

Completed

Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Undergoing an Elective Procedure

Thrombocytopenia Associated With Liver Disease

United States, China, Spain, Argentina, Belgium, Israel, Mexico, Romania, Japan, Brazil, Russian Federation, Germany, Italy, Czechia, Canada, Australia, France
Eisai Inc.

Completed

Treatment of Thrombocytopenia in Patients With Chronic Liver DiseaseUndergoing an Elective Procedure

Thrombocytopenia Associated With Liver Disease

United States, Italy, China, Taiwan, Spain, Belgium, Poland, Portugal, Canada, Korea, Republic of, Australia, Brazil, Chile, Austria, Germany, Hungary, France, Argentina, United Kingdom, Thailand
Institute of Hematology & Blood Diseases Hospital
Henan Cancer Hospital; Tianjin Medical University Cancer Institute and Hospital and other collaborators

Recruiting

Avatrombopag for Chemotherapy-induced Thrombocytopenia

Chemotherapy-induced Thrombocytopenia | Avatrombopag

China
Memorial Sloan Kettering Cancer Center
Sobi, Inc.

Withdrawn

Avatrombopag for Thrombocytopenia in People With Cancer

Liver Diseases | Cancer | Thrombocytopenia
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Efficacy and Safety of Avatrombopag for Treating TCP in HBV-ACLF Patients Receiving ALSS Treatment

Acute-On-Chronic Liver Failure | Hepatitis B, Chronic | Thrombocytopenia

China
Institute of Hematology & Blood Diseases Hospital...

Recruiting

Avatrombopag in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies

Connective Tissue Diseases | Immune Thrombocytopenia | Autoantibodies | Evan Syndrome

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

Efficacy and Safety of CSA and Avatrombopag for the Treatment of SAA in the Elderly (SAA)

Severe Aplastic Anemia

China
Sobi, Inc.

Withdrawn

Open-Label Study to Evaluate the Safety and Efficacy of Avatrombopag and Remission Rates in Adults With ITP of ≤6 Months

Immune Thrombocytopenia
Eisai Inc.

Completed

A Open-label, Three-period, Partial-replicate Design Study to Evaluate the Inter- and Intrasubject Variability of the Avatrombopag To-be-marketed Formulation Administered as Single Doses of 40 mg to Healthy Subjects Receiving a Low-fat Meal

Healthy Volunteers

United States
Eisai Inc.

Completed

Chronic Hepatitis C Virus Related Thrombocytopenia to Evaluate the Effects of E5501

Thrombocytopenia

United States
Eisai Inc.

Completed

Efficacy and Safety of Oral E5501 Plus Standard of Care for the Treatment of Thrombocytopenia in Adults With Chronic Immune Thrombocytopenia (Amendment 02)

Immune Thrombocytopenia | Chronic Thrombocytopenia

Poland, Ukraine, Belgium, Bulgaria, South Africa, Netherlands, New Zealand, Singapore, Australia, Slovakia, Czechia
Eisai Inc.

Terminated

A Phase 3, Multicenter, Randomized, Double-blind,Active-controlled, Parallel-group Trial With an Open-labelExtension Phase to Evaluate the Efficacy and Safety of OralE5501 Versus Eltrombopag, in Adults With Chronic ImmuneThrombocytopenia (Idiopathic Thrombocytopenic Purpura)

Idiopathic Thrombocytopenic Purpura

United States
Chinese PLA General Hospital

Recruiting

Efficacy of Avatrombopag in Thrombocytopenic Patients With Chronic Liver Disease Undergoing an Elective Procedure

Chronic Liver Disease | Thrombocytopenia; Drugs

China
Tongji Hospital
The First Affiliated Hospital of Nanchang University; The First Hospital of... and other collaborators

Recruiting

Avatrombopag in Patients With End-stage Liver Disease and Thrombocytopenia

Liver Failure | Decompensated Cirrhosis | Thrombocytopenia

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

Efficacy and Safety of Avatrombopag Combined With IST for the Treatment of HAAA and SAA With Abnormal Liver Function

Aplastic Anemia

China
Peking Union Medical College Hospital

Recruiting

Efficacy and Safety of CsA+AVA in the Treatment of NSAA in the Elderly

Aplastic Anemia

China
Casa di Cura Privata Villa Mafalda

Recruiting

Desogestrel Versus GnRH Antagonist in IVF/ICSI (DEGOS)

Infertility | IVF

Italy
Peking Union Medical College Hospital

Not yet recruiting

CsA+ATG+AVA vs. CsA+AVA for the Treatment of Newly-diagnosed SAA in the Elderly

Aplastic Anemia

China
The First Affiliated Hospital of Soochow University

Not yet recruiting

Decitabine for Poor Graft Function Post Allo-HSCT

Poor Graft Function
IVI Madrid

Completed

DuoStim in Cases of PGT: Comparison of Embryo Quantity and Embryonic Quality Using MitoScore

Infertility, Female

Spain
Eisai Inc.

Completed

Study to Assess Pharmacokinetic Drug-Drug Interaction Between Avatrombopag When Co-Administered With Fluconazole, Itraconazole, or Rifampin in Healthy Subjects

Healthy Participants

United States

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