Movement Pattern in Patients With Hip Dysplasia

Movement Pattern in Patients With Hip Dysplasia Operated With Minimally Invasive Approach in Peri-acetabular Osteotomy (PAO)

The purpose of this study is to examine the movement pattern in patients with hip dysplasia preoperative, six and 12 month after minimally invasive approach for Periacetabular osteotomy (PAO). Secondary to examine the movement pattern in patients compared to healthy controls and historical data.

Study Overview

• Status: Completed
• Conditions: Hip Dysplasia
• Intervention / Treatment: Procedure: Minimally invasive approach for Periacetabular osteotomy

Detailed Description

Congenital hip dysplasia is a disease characterised by pathological changes in the hip joint. Hip dysplasia is a normal disease with a prevalence of 4.3% in men and 3.6 in woman. Untreated hip dysplasia is a known cause of developing osteoarthritis early in life and symptoms as pain, hip instability together with a changed gait pattern are normal. Symptomatic hip dysplasia is seen in patients between 15 and 55 years and can be unilateral as well as bilateral. Causes of hip dysplasia are described as genetic, mechanic or hormonal.

Today patients with hip dysplasia are offered a hip conserving surgery before the osteoarthritis has developed. In 2003 a minimally invasive approach for periacetabular osteotomy (PAO) was introduced at Aarhus University Hospital. An advantage of minimally invasive approach compared to the classical Bernese periacetabular osteotomy is minimal impact of the soft tissues in the hip region.

Hip pain and activity limitations highly affect quality of life and physical function. The gait distance is reduced and patients have to compensate to relieve the pressure on the hip joint. Knowledge about the dynamics of the gait and running pattern in patients with dysplasia is important to understand the consequences of the dysplastic hip joint. Furthermore knowledge about gait compensations is relevant for the clinicians in the management and treatment of patients with hip dysplasia.

Today, gait and running compensation is unknown after minimally invasive approach The purpose of this study is, therefore, to examine the movement pattern in patients with hip dysplasia preoperative, six and 12 month after minimally invasive approach for Peri-acetabular osteotomy (PAO). Secondary to examine the movement pattern in patients compared to healthy controls and historical data.

• Study Type: Observational
• Enrollment (Actual): 55

Contacts and Locations

Study Locations

• Denmark
  • Aarhus, Denmark, 8000
    • Aarhus University Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 14 years to 56 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Patients diagnosed with hip dysplasia and waiting for surgery.

Description

Inclusion Criteria:

• Patients diagnosed with hip dysplasia
• Patients in the age of 18-60 years
• Patients, who can speak, understand and read Danish

Exclusion Criteria:

• Persons with hip dysplasia secondary to other hip conditions such as Calvé Perthes and epiphysiolysis.
• Persons who have had alloplastic surgery in the hip, knee or ankle.
• Persons with diseases that affect the gait pattern.
• Persons with serious hip, knee, ankle or back pain.

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Prospective

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
hip dysplasia; Patients with hip dysplasia	Procedure: Minimally invasive approach for Periacetabular osteotomy; A peri-acetabular osteotomy is a surgery performed to correct the dysplastic acetabulum and reduce joint contact pressures and early osteoarthritis.; Other Names: PAO (periacetabular osteotomy)
Healthy people; Enrolled from the patients acquaintance circle

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Hip flexion's muscle moment in stance evaluated in gait, run and jump test	Examined using 3D Movement Capture System	Preoperative (baseline), 6 and 12 month postoperative

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Hip extension angle evaluated in gait, run and jump test	Examined using 3D Movement Capture Systen	Preoperative (baseline), 6 and 12 month postoperative
On-set of the hip muscles evaluated in gait, run and jump test	Examined using skin electromyography (EMG)	Preoperative (baseline), 6 and 12 month postoperative
Function, sports and recreational activities	Evaluated with Hip Dysfunction and Osteoarthritis Outcome Score (HOOS) and The Copenhagen Hip and Groin Outcome Score (HAGOS)	Preoperative (baseline), 6 and 12 month postoperative
Quality of life	Evaluated with Hip Dysfunction and Osteoarthritis Outcome Score (HOOS) and The Copenhagen Hip and Groin Outcome Score (HAGOS)	preoperative (baseline), 6 and 12 month postoperative

Collaborators and Investigators

• Sponsor: Aarhus University Hospital
• Investigators: Principal Investigator: Julie S Jacobsen, MSc, Aarhus University Hospital; Principal Investigator: Inger Mechlenburg, MSc, PhD, Aarhus University Hospital; Study Chair: Kjeld Søballe, Prof. Dr.med, Aarhus University Hospital; Study Chair: Henrik Sørensen, PhD, University of Aarhus; Study Chair: Dennis Nielsen, MSc, University of Aarhus

Publications and helpful links

General Publications

• Sorensen H, Skalshoi O, Nielsen DB, Jacobsen JS, Soballe K, Mechlenburg I. Hip muscle and joint contact forces before, 6 and 12 months after minimally invasive periacetabular osteotomy. Hip Int. 2021 Sep;31(5):676-682. doi: 10.1177/1120700020925411. Epub 2020 May 4.

Study record dates

Study Major Dates

• Study Start: March 1, 2011
• Primary Completion (Actual): March 1, 2013
• Study Completion (Actual): March 1, 2013

Study Registration Dates

• First Submitted: April 27, 2011
• First Submitted That Met QC Criteria: April 28, 2011
• First Posted (Estimate): April 29, 2011

Study Record Updates

• Last Update Posted (Estimate): April 5, 2013
• Last Update Submitted That Met QC Criteria: April 4, 2013
• Last Verified: April 1, 2013

More Information

Terms related to this study

• Keywords: Quality of life; Hip dysplasia; Physical function; Hip pain; Movement capture system; Movement analysis
• Additional Relevant MeSH Terms: Pathologic Processes; Wounds and Injuries; Congenital Abnormalities; Joint Diseases; Musculoskeletal Diseases; Hip Injuries; Musculoskeletal Abnormalities; Joint Dislocations; Hyperplasia; Hip Dislocation; Developmental Dysplasia of the Hip; Hip Dislocation, Congenital
• Other Study ID Numbers: M-20100206