How Fat Influences the Brain

January 18, 2012 updated by: Sabine Frank, University Hospital Tuebingen

Fat Intake Modulates Cerebral Blood Flow in Homeostatic and Gustatory Brain Areas in Humans

The aim of the current study was to investigate the effect of a high versus a low fat meal (operationalized by high and low fat yoghurt) on homeostatic and gustatory brain regions.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

11

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Germany
      • Tuebingen, Germany, 72076
        • University Clinic of Tuebingen, MEG Center

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

25 years to 32 years (ADULT)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

Male

Description

Inclusion Criteria:

  • male
  • healthy

Exclusion Criteria:

  • lactose intolerance
  • fMRI contraindications (metal implants,...)

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: BASIC_SCIENCE
  • Allocation: RANDOMIZED
  • Interventional Model: PARALLEL
  • Masking: SINGLE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
EXPERIMENTAL: high fat yoghurt intake
500 ml of a high fat yoghurt
Dietary supplement: intake of high or low fat yoghurt
intake of 500 ml of a high fat yoghurt on one day and intake of 500 ml of a low fat yoghurt on the other day
EXPERIMENTAL: low fat yoghurt intake
Dietary supplement: intake of high or low fat yoghurt
intake of 500 ml of a high fat yoghurt on one day and intake of 500 ml of a low fat yoghurt on the other day

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Changes in Cerebral Blood Flow due to the high or low fat yoghurt intake after 30 minutes and 120 minutes compared to a baseline measurement 30 minutes before yoghurt intake.
Time Frame: 30 minutes before as well as 30 minutes and 120 minutes after fat intake

We were interested in differential brain activations due to the high or low fat meal. To assess this, the mentioned time points are suitable.

The Cerebral Blood Flow is measured using Arterial Spin Labeling sequences in a functional magnetic resonance tomography.
30 minutes before as well as 30 minutes and 120 minutes after fat intake

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University Hospital Tuebingen

Collaborators

German Research Foundation
University of Hohenheim
German Center for Diabetes Research
German Federation of Industrial Research Associations
Zentrum für Ernährungsmedizin und Prävention

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2011

Primary Completion (ACTUAL)

March 1, 2011

Study Completion (ACTUAL)

March 1, 2011

Study Registration Dates

First Submitted

January 9, 2012

First Submitted That Met QC Criteria

January 18, 2012

First Posted (ESTIMATE)

January 24, 2012

Study Record Updates

Last Update Posted (ESTIMATE)

January 24, 2012

Last Update Submitted That Met QC Criteria

January 18, 2012

Last Verified

January 1, 2012

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • YOG

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Fat Processing in the Brain

Clinical Trials on intake of high or low fat yoghurt

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Spain

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

3
Subscribe