Histological Change of The Dentinal-Pulp Complex and Root Resorption

Histological Changes of The Dentinal-Pulp Complex and Root Resorption in Maxillary Premolars With Intrusive Orthodontic Movements Under a Low Power Laser Effect

The purpose of the study is evaluate the histological changes of the dentinal-pulp complex and root resorption in maxillary premolars with intrusive orthodontic movement under a low power laser effects.

Study Overview

• Status: Completed
• Conditions: Laser; Intrusion; Histology; Resorption
• Intervention / Treatment: Radiation: Low power laser in teeth after intrusive movement; Other: Simulated laser in teeth with intrusive movements

Detailed Description

Orthodontics movements can cause inflamatory changes in the pulp and external inflamatory root resorption, different methods have been suggested to control that changes as the use of the low power laser. The objective of this study is to evaluate the low power laser effect on the inflamatory pulpar change and inflamatory external root resorption in maxillary premolars with intrusive orthodontic movements of 4 ounces during 12 weeks. Total sample were 34 healthy teeth, 16 were used to evaluate the normal standar and 18 were divided in two groups, the experimental group with the low power laser effect had a dose of 18 joules after activations of the orthodontic intrusion and the control group had a simulated effect in the same orthodontic movement. Teeth were extacted after 12 weeks and histological changes were evaluated in the dentinal-pulp complex and the pesence of external inflamatory root resorption. Findins suggest that low power. Laser decreased the inflamatory changes of the dentinal - pulp complex and the severity of the external inflamatory root resorption.

• Study Type: Interventional
• Enrollment (Actual): 34
• Phase: Phase 2; Phase 1

Contacts and Locations

Study Locations

• Colombia
  • Antioquia
    • Medellin, Antioquia, Colombia, 00000
      • Paula Villa M

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 13 years to 23 years (Child, Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Patients with first premolar extraction indicated
• Patients with no sistemic diseases
• Healthy premolars with completed root and no trauma or restoration

Exclusion Criteria:

• Sistemics diseased
• Restoration, trauma in first premolars
• root uncompleted

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Basic Science
• Allocation: Non-Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Teeth with intrusive movement and low power laser; Histological changes and root resorption were assesed in Teeth with intrusive movement after a low power laser application	Radiation: Low power laser in teeth after intrusive movement; Low power laser was aplied to premolar teeth under an intrusive movement to study histological changes and root resorption
Experimental: Teeth with intrusive movements with no laser; Histological changes and root resorption in Teeth with intrusive movements with no laser	Other: Simulated laser in teeth with intrusive movements; Simulated laser in teeth with intrusive movements for histological and root resorption changes

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Teeth with intrusive movement and low power laser	Histological changes and root resorption were assesed in Teeth with intrusive movement after a low power laser application	12 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Teeth with intrusive movements with no laser exposition	Histological changes and root resorption were assesed in Teeth with intrusive movement with no laser exposition	12 weeks

Collaborators and Investigators

• Sponsor: Universidad de Antioquia

Publications and helpful links

Helpful Links

• Related Info

Study record dates

Study Major Dates

• Study Start: June 1, 2006
• Primary Completion (Actual): May 1, 2008
• Study Completion (Actual): May 1, 2009

Study Registration Dates

• First Submitted: July 13, 2012
• First Submitted That Met QC Criteria: July 16, 2012
• First Posted (Estimate): July 17, 2012

Study Record Updates

• Last Update Posted (Estimate): July 17, 2012
• Last Update Submitted That Met QC Criteria: July 16, 2012
• Last Verified: July 1, 2012

More Information

Terms related to this study

• Keywords: root resorption; low-power laser; orthodontic tooth movement; pulp changes
• Additional Relevant MeSH Terms: Stomatognathic Diseases; Tooth Diseases; Tooth Resorption; Root Resorption
• Other Study ID Numbers: 2006-007