The Effect of Thyme and Sumac on the Thermic Effect of Food and Comparison Between Warm and Cold Temperament People

The purpose of this study is to determine the effect of Zataria multiflora Boiss and Sumac on the thermic effect of food, activity of sympathetic - parasympathetic system: comparison between warm and cold temperament people.

Study Overview

• Status: Unknown
• Conditions: Effects of; Food, Allergic
• Intervention / Treatment: Other: Sumac; Other: Zataria multiflora Boiss

Detailed Description

Human body needs to energy in order to preserve life.There are three forms of energy consumption at body, consumption at baseline or resting, consumption at energy expenditure for Thermic effect of food and energy is spent in physical activity.Also from the perspective of traditional medicine, cold and warm natured people are determined based on certain mental and physical protests.

There are different temperament not only in Traditional Iranian Medicine, but in traditional Chinese medicine, Indian, Greek, Arabic, Romanian, and there are European.As various factors on the basal metabolism and thermic effect of food , also are several factors such as age, sex, physical condition of the environment that have an impact on individual temperament.

Since the protests seem warm and cool temperament and factors affecting on their basal metabolic rate and thermogenesis so that food may explain the relationship between warm and cold temperament to mind is the basal metabolism; It seems those are hot temperament, their basal metabolic rate is higher BMR than normal and those who are cold temperament, have a lower BMR.

On the other hand seems that thermic effect of food in people who have hot temperament is higher than thermic effect of food in people who have cold temperament.

So that we need to use of two nutrient foods, in this way we consided the multiple criteria and then were selected sumac and thyme.

On the other hand, in order to study possible mechanisms affecting basal metabolism, thermogenesis of food, according to previous studies and also matches that there are between sympathetic - parasympathetic and thyroid function, with symptoms of cold and warm temperament there, checking of activity of these organs seems necessary.

Because to maintain basal metabolic rate is essential for human life, so that each factor in order to better understand these is helpful to human life.And the need for such study makes clear;Through this step help toward improving public health

• Study Type: Interventional
• Enrollment (Anticipated): 40
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Iran, Islamic Republic of
  • Tehran, Iran, Islamic Republic of
    • Tehran University of Medical Sciences

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 40 years (ADULT)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion criteria:

• Age 18 to 40 years
• Having to suffer any ill health and lack of attention to history and physical examination
• Willing to cooperate with the project

Exclusion Criteria:

• Catching any disease.
• Use of specific dietary patterns such as vegetarianism
• Having a BMI outside the normal range
• Use of any drugs or supplements in past month
• Allergic reaction to food allergy and non-prescription
• An unwillingness to cooperate in any of the stages of implementation

Study Plan

How is the study designed?

Design Details

• Allocation: RANDOMIZED
• Interventional Model: CROSSOVER
• Masking: DOUBLE

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
OTHER: sumac; Thermic effect of food of Sumac and comparison between hot and cold temperament people	Other: Sumac; Thermic effect of food of Sumac and comparison between hot and cold temperament people; Other Names: sumach
OTHER: Zataria multiflora Boiss; Thermic effect of food of Zataria multiflora Boiss and comparison between hot and cold temperament people	Other: Zataria multiflora Boiss; Thermic effect of food of Zataria multiflora Boiss and comparison between hot and cold temperament people; Other Names: Thyme

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Thermic Effect of Food (TEF)	kilocalorie(kcal) and by indirect calorimetery	Change from baseline to 4 hours And repeated 1 week later

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
activity of sympathetic - parasympathetic system(Epinephrine, Norepinephrine, Cortisol)	ng/ml	Change from baseline to 4 hours And repeated 1 week later

Collaborators and Investigators

• Sponsor: Tehran University of Medical Sciences
• Investigators: Principal Investigator: Ahmadreza Dorosty Motlagh, PhD, Tehran University of Medical Sciences, Tehran, Iran

Study record dates

Study Major Dates

• Study Start: August 1, 2012
• Primary Completion (ANTICIPATED): August 1, 2013
• Study Completion (ANTICIPATED): August 1, 2014

Study Registration Dates

• First Submitted: July 15, 2012
• First Submitted That Met QC Criteria: July 16, 2012
• First Posted (ESTIMATE): July 17, 2012

Study Record Updates

• Last Update Posted (ESTIMATE): July 17, 2012
• Last Update Submitted That Met QC Criteria: July 16, 2012
• Last Verified: July 1, 2012

More Information

Terms related to this study

• Keywords: Zataria multiflora Boiss Sumac TEF temperament
• Other Study ID Numbers: 90-04-27-15366