Comparison of the Evaluation of CAD by CT AngioScan and Coronary Angiogram (CTAS-MCAS)

January 29, 2013 updated by: Université de Sherbrooke

Comparison of the Evaluation of CAD by CT AngioScan and Coronary Angiogram in Patient as Part of Preoperative Evaluation in Ascending Aorta Replacement Surgery Patients.

The use of CT Coronary Angioscan (CT-AS) is gaining popularity, but its exact value as evaluation of CAD requires confirmation. We intend to compare the results of CT-AS and convention coronary angiogram results in patients who are scheduled for an ascending aorta aneurysm reparation surgery. These examens are standard of care before this surgery, so there is no additional danger or disadvantage for the patient. We hope to confirm that CT-AS is a reliable screening test for CAD in patient undergoing heart surgery for other reason than CAD.

Study Overview

Status

Unknown

Conditions

Coronary Artery Disease

Study Type

Observational

Enrollment (Anticipated)

100

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Canada
- Quebec
  - Sherbrooke, Quebec, Canada, J1H 5N4
    - Recruiting
    - CHUS Fleurimont
    - Contact:
      
      Paul Farand, M.Sc
      
      Phone Number: 819-346-1110
      
      Email: paul.farand@sherbrooke.ca
    - Principal Investigator:
      
      Gérald Gahide, MD
    - Sub-Investigator:
      
      Paul Farand, MD, MSc
    - Sub-Investigator:
      
      Tamas Z Fulop, MD
    - Sub-Investigator:
      
      Francis Rivest, MD

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 89 years (Adult, Older Adult)

Accepts Healthy Volunteers

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Patients with ascending aorta aneurysm undergoing preoperative evaluation of CAD by CT-Angioscan and Coronary angiogramm before surgical reparation.

Description

Inclusion Criteria:

Ascending aorta aneurysm waiting for surgical correction
Willing to participate
Needing a Coronary angiogram and a CT-AS for medical reasons

Exclusion Criteria:

Refuse to participate
Allergy to contrast material
Incomplete results or having one of the test done in another hospital
Arrythmia
More than 6 months between the two exams

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Presence of CAD Time Frame: less than 6 monthes between two tests	The CAD seen on CT-AS as compared to the results of the gold-standard test of coronary angiogram.	less than 6 monthes between two tests

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Université de Sherbrooke

Investigators

Principal Investigator: Gerald Gahide, MD PHD, Université de Sherbrooke

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2013

Primary Completion (Anticipated)

February 1, 2015

Study Completion (Anticipated)