Anti-Mullerian Hormone Changes After Laparoscopic Ovarian Cystectomy for Endometrioma Compared With the Non-ovarian Conditions

This aim of the study is to evaluate the impact of endometrioma and laparoscopic cystectomy on ovarian reserve as measured by serum antimullerian hormone and to study the different effects of levels of serum antimullerian hormone between laparoscopic cystectomy and the non-ovarian pelvic surgery.

Study Overview

• Status: Unknown
• Conditions: Ovarian Reserve

• Study Type: Observational
• Enrollment (Anticipated): 56

Contacts and Locations

Study Locations

• Thailand
  • Pathumthanee
    • Rangsit, Pathumthanee, Thailand, 12120
      • Recruiting
      • Faculty of medicine , Thammasat university
      • Contact: Chamnan Tanprasertkul; Phone Number: 66896999240; Email: chamnandoctor@gmail.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 45 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: Female

• Sampling Method: Non-Probability Sample

Study Population

Reproductive women , age 18- 45 years who undergo laparoscopic ovarian cystectomy or laparoscopic non- ovarian pelvic surgery

Description

Inclusion Criteria:

• • Participants must be between the ages of 18 - 45 during enter the study .

  • Every participants have to completely understand the process of this study and have written informed consent .
  • Having regular menstrual cycles (21-35 days) at the time of operation
  • no evidence of any other endocrine disorders such as diabetes mellitus, thyroid dysfunction, hyperprolactinemia, congenital adrenal hyperplasia, Cushing's syndrome, or adrenal insufficiency.
  • undergo laparoscopic ovarian cystectomy or laparoscopic non- ovarian pelvic surgery for benign pelvic disease
  • No previous history of adnexal surgery
  • No any suspicious findings of malignant ovarian diseases
  • Never taking any medication such as oral pill and hormonal drugs within 3 months before the enrollment.
  • pathological diagnosis of excised ovarian tissue confirm as endometriotic cyst in study group and other benign pelvic disease in control group

Exclusion Criteria:

• polycystic ovarian syndrome according to the Rotterdam criteria

  • pathological report as the malignant diseases
  • have operation conversion to open-laparotomy

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
laparoscopic ovarian cystectomy; the group who laparoscopic ovarian cystectomy are performed for endometrioma
laparoscopic non- ovarian pelvic surgery; the group whom laparoscopic non- ovarian pelvic surgery are performed

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Serum AMH levels	6 months

Collaborators and Investigators

• Sponsor: Thammasat University

Study record dates

Study Major Dates

• Study Start: December 1, 2012
• Primary Completion (Anticipated): December 1, 2013

Study Registration Dates

• First Submitted: August 6, 2013
• First Submitted That Met QC Criteria: August 6, 2013
• First Posted (Estimate): August 9, 2013

Study Record Updates

• Last Update Posted (Estimate): August 9, 2013
• Last Update Submitted That Met QC Criteria: August 6, 2013
• Last Verified: August 1, 2013

More Information

Terms related to this study

• Other Study ID Numbers: MTU-OB-3-096/56