Continuous Local Anesthesia Versus Continuous Femoral Nerve Bloc After Total Knee Arthroplasty: Impact on Mean Discharge Aptitude Delay (GLASGOW)

August 24, 2018 updated by: University Hospital, Strasbourg, France
This study aims at comparing continuous local anesthesia and femoral nerve bloc for total knee arthroplasty in terms of post-operative recovery.

Study Overview

Status

Terminated

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

36

Phase

  • Phase 4

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • France
      • Illkirch-Graffenstaden, France, 67400
        • CCOM-Hôpitaux Universitaires de Strasbourg

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Total knee arthroplasty
  • Age > 18 years with social security covering.
  • Written informed consent

Exclusion Criteria:

  • Age < 18 years
  • ASA Physical Status > III
  • Body weight < 50 kg
  • Latex or silver allergy.
  • Loco-regional anesthesia contraindication
  • Chronic anticoagulant, corticoid or pain treatment.
  • Rivaroxaban or enoxaparin contraindication
  • Communication issues
  • Patient under guardianship
  • Pregnant or breast-feeding patient

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Continuous femoral nerve bloc
Drug: Ropivacaine
Experimental: Continuous local anesthesia
Continuous local infiltration of local anesthetic in the operated knee.
Drug: Ropivacaine

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Discharge ability time period
Time Frame: Participants will be followed for the duration of hospital stay, an expected average of 10 days
Participants will be followed for the duration of hospital stay, an expected average of 10 days

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University Hospital, Strasbourg, France

Investigators

  • Principal Investigator: Jean-Yves JENNY, MD, Hôpitaux Universitaires de Strasbourg

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 1, 2014

Primary Completion (Actual)

April 1, 2016

Study Completion (Actual)

August 12, 2017

Study Registration Dates

First Submitted

November 27, 2013

First Submitted That Met QC Criteria

December 4, 2013

First Posted (Estimate)

December 10, 2013

Study Record Updates

Last Update Posted (Actual)

August 28, 2018

Last Update Submitted That Met QC Criteria

August 24, 2018

Last Verified

August 1, 2018

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 5560

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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