- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02155127
Effects of a Walking Intervention in Older Patients With Chronic Kidney Disease: Feasibility Study
November 16, 2016 updated by: Patricia Painter, University of Utah
Chronic kidney disease (CKD) affects more than 26 million individuals (13 percent) of the U.S. population, with a projected 70 percent increase by the year 2015 to over 40 million individuals.
Impairments in physical function and mobility limitations have been reported in older Chronic Kidney Disease patients, however the consequences of impaired functioning on participation in daily life and quality of life have not been studied.
Early identification and interventions to mitigate deterioration in physical function and mobility should lead to improved health and quality of life outcomes in older patients with Chronic Kidney Disease.
Although older individuals with Chronic Kidney Disease have reduced survival expectancy, maintaining physical function and mobility may contribute to longer active life expectancy, and higher quality of life despite their diagnosis.
Study Overview
Study Type
Interventional
Enrollment (Actual)
80
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Utah
-
Salt Lake City, Utah, United States, 84112
- University of Utah
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-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
60 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Male and female patients over the age of 60 years
- Diagnosed with moderate to severe CKD (stage 2-4)
- Ambulatory (with or without use of an assistive device such as a cane or walker)
- Living in the community, cognitively able to provide consent and understand directions for the tests
- Cognitive ability to understand and carry out an independent home walking program
- Access and ability to communicate with study staff on a weekly basis and available for follow-up testing.
Exclusion Criteria:
- Inability to carry out a program of walking independently at home
- Unavailable for follow-up testing, estimated GFR >60 ml/minx1.73m2 and < 15 ml/minx1.73 m2
- Recent cardiac event (within the past 6 months)
- Uncontrolled hypertension
- Uncontrolled diabetes
- Pulmonary disease that may limit the ability to progress with walking
- Progressive neuromuscular disease
- Any orthopedic or neuromuscular condition that may be exacerbated by increased walking activity
- diabetic foot ulcer.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: walking intervention
Subjects are randomized to walking/functional strength program with weekly coaching or usual care.
The program is for 12 weeks.
The intervention includes 3 lower extremity strengthening exercises, and progressive walking.
|
|
No Intervention: usual care
these subjects receive information on walking program, however do not receive any coaching over 12 weeks
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
walking speed
Time Frame: baseline to 3 months
|
baseline to 3 months
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Patricia L Painter, Ph.D., University of Utah
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
October 1, 2014
Primary Completion (Actual)
October 1, 2016
Study Completion (Actual)
October 1, 2016
Study Registration Dates
First Submitted
June 2, 2014
First Submitted That Met QC Criteria
June 2, 2014
First Posted (Estimate)
June 4, 2014
Study Record Updates
Last Update Posted (Estimate)
November 18, 2016
Last Update Submitted That Met QC Criteria
November 16, 2016
Last Verified
November 1, 2016
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- IRB_00064407
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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