- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02189564
Rewarding Feedback in Motor Learning and Rehabilitation (KFSP-REWARD)
Die Auswirkung Von Dopaminergen Belohnungsreizen Auf Das Lernen Einer Motorischen Fertikgeit Bei Gesunden Probanden "Effects of Dopaminergic Reward on Motor Skill Learning in Healthy Subjects"
The effect of rewarding vs. non-rewarding feedback on acquisition of a motor skill is investigated in a single blinded parallel group design. Reward consists of performance dependent monetary reward, or of knowledge of performance in selected (above average) trials.
The investigators hypothesize improved motor skill learning and higher involvement of the dopaminsrgic system under rewarding vs. non-rewarding conditions.
Study Overview
Status
Conditions
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Contacts and Locations
Study Locations
-
-
Lucerne
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Vitznau, Lucerne, Switzerland, 6354
- Cereneo, Center For Rehabilitation and Neurology
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- neurologically healthy
- right handed
Exclusion Criteria:
- Contraindications against magnetic resonance imaging
- pregnancy
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Basic Science
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Active Comparator: Intrinsic reward
Feedback about good performance
|
|
|
Experimental: Intrinsic and extrinsic reward
Feedback about good performance + money
|
|
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Experimental: Intrinsic reward (average performance)
Feedback about random selection of trials
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Motor skill learning using an arc pointing task
Time Frame: about 10 minutes pre-training, about 10 min post training, about 24h post training
|
temporal and spacial precision in an arc pointing task will be assessed using 5 different movement speeds during the above mentioned time periods before and after a specific motor learning programm.
Learning will be assessed as change from pre-training to post training
|
about 10 minutes pre-training, about 10 min post training, about 24h post training
|
Collaborators and Investigators
Sponsor
Collaborators
Publications and helpful links
Study record dates
Study Major Dates
Study Start
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Other Study ID Numbers
- KFSP-SUB1-LU13054
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