Vitamin D Status and Immune Function

April 4, 2017 updated by: Bangor University

Vitamin D Status and in Vivo Immune Function

The purpose of this study is to examine the relationship between Vitamin D status and immunity.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Vitamin D is mainly obtained from the sun and follows a seasonal pattern, with Vitamin D levels peaking in summer and reaching a trough during winter. Vitamin D deficiency is associated with impaired immunity. However, knowledge of Vitamin D deficiency with in vivo immunity is limited. This observational study aims to investigate the relationship between Vitamin D status and the in vivo immunity.

Study Type

Observational

Enrollment (Actual)

264

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United Kingdom
    • North Yorkshire
      • Catterick, North Yorkshire, United Kingdom, DL9 3PS
        • Infantry Training Centre

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 35 years (Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Young adults who are starting basic training in the army.

Description

Inclusion Criteria:

  • Passed medical assessment by medical doctor
  • Passed audio test (this is part of medical assessment)
  • Met physical fitness requirements

Exclusion Criteria:

• Medically deferred by medical doctor

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Army recruits
Army recruits at the start of basic training will complete an in vivo immunity model
Other: In vivo immunity model
A measure of in vivo immune function.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Vitamin D measured by liquid chromatography tandem mass spectroscopy
Time Frame: Up to 20 months
Circulating 25-hydroxy-vitamin D
Up to 20 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Immune function measured by analytic biochemistry assay
Time Frame: Up to 20 months
In vivo immune measure
Up to 20 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Bangor University

Collaborators

University of East Anglia

Investigators

  • Principal Investigator: Julie Greeves, PhD, HQ Army Research and Training Division

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

April 1, 2014

Primary Completion (Actual)

December 1, 2015

Study Completion (Actual)

December 1, 2015

Study Registration Dates

First Submitted

March 25, 2015

First Submitted That Met QC Criteria

April 9, 2015

First Posted (Estimate)

April 15, 2015

Study Record Updates

Last Update Posted (Actual)

April 5, 2017

Last Update Submitted That Met QC Criteria

April 4, 2017

Last Verified

March 1, 2017

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 165/Gen/10

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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