Documentation of Heart Failure in a Gulf Registry (DYSPNEA)

Gulf Documentation of Ambulatory Sick Patients With Heart Failure Registry

In the Middle East and the Gulf, the general population have high cardiovascular risks like diabetes, hypertension, smoking and obesity. The average age of a patient with an acute coronary syndrome (ACS) event is relatively young compared to Western populations. Women are multiparous and the rates of consanguinity marriages are high in this region of the world. These risk factors and conditions result in heart failure. Great deal of knowledge is missing regarding the influence of these risk factors on heart failure presentation, the causes and management of heart failure in ambulatory patients in this region of the world.

Study Overview

• Status: Completed
• Conditions: Heart Failure

• Study Type: Observational
• Enrollment (Actual): 3680

Contacts and Locations

Study Locations

• Kuwait
  • Kuwait City, Kuwait
    • Adan hospital
  • Kuwait City, Kuwait
    • Amiri Hospital
  • Kuwait City, Kuwait
    • Chest Hospital
  • Kuwait City, Kuwait
    • Farwanya Hospital
  • Kuwait City, Kuwait
    • Mubarak Al Kabeer

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 21 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

4,000 patients already diagnosed with heart failure. Expected number of patients from each country: Kuwait 1200, Oman 1200, UAE 600, Bahrain 600 and Qatar 400.

Description

Inclusion Criteria:

1. Is over the age of 21.
2. Has been diagnosed with heart failure, regardless of cause.
3. Is presenting to the outpatient clinic of an internist or cardiologist for follow up.
4. Provides a written consent.

Exclusion Criteria:

1. Prior enrolment in this study.
2. Refusal or inability to provide consent.

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Quantifying the causes of heart failure in the ambulatory patients in the outpatient setting	Number of participants with main reason due to heart failure from Coronary Artery Disease (CAD), Hypertension, Valvular, Idiopathic Dilated Cardiomyopathy, Congenital, Pregnancy / delivery related, or other reason to be specified	Single time point at baseline upon inclusion (cross-sectional)

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Measure investigations that heart failure patients undergo	Number of participants who have had echocardiography done less than 1 month, 1-6 months, greater than 6 months from enrollment	Up to 6 months before inclusion
Measuring patient functional status in heart failure patients	Number of participants who can walk independently, walk with assistance, or are unable to walk.; Number of participants who are limited in dressing, somewhat limited, or not limited.; Number of participants who are can shower in a limited manner, somewhat limited, or not limited	Single time point at baseline upon inclusion (cross-sectional)
Relationship between cardiovascular risk factors and heart failure		Single time point at baseline upon inclusion (cross-sectional)
Measuring Management Gaps in heart failure patients	Number of participants with 0, 1, 2, or greater than 2 emergency room visits related to heart failure; Number of participants with 0,1, 2, or greater than 2 hospital admissions related to heart failure	Past 12 months upon inclusion

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Quantifying the distribution of heart failure types	Number of participants that will either have preserved or reduced left ventricular systolic function	Single time point at baseline upon inclusion (cross-sectional)

Collaborators and Investigators

• Sponsor: Gulf Heart Association
• Investigators: Principal Investigator: Mohammad Zubaid, Gulf Heart Association

Publications and helpful links

General Publications

• Zubaid M, Rashed W, Ridha M, Al-Jarallah M, Hamad A, Al Banna R, Sulaiman K, Bazargani N, Almahmeed W, Al Mulla A, Baslaib F, Asaad N, Attur S. Design and Rationale of Gulf Documentation of Ambulatory Sick Patients with Heart Failure (Gulf DYSPNEA) Registry. Heart Views. 2018 Jul-Sep;19(3):81-84. doi: 10.4103/HEARTVIEWS.HEARTVIEWS_9_18.

Study record dates

Study Major Dates

• Study Start (Actual): November 7, 2016
• Primary Completion (Actual): February 19, 2018
• Study Completion (Actual): February 19, 2018

Study Registration Dates

• First Submitted: May 15, 2016
• First Submitted That Met QC Criteria: June 2, 2016
• First Posted (Estimate): June 8, 2016

Study Record Updates

• Last Update Posted (Actual): May 9, 2018
• Last Update Submitted That Met QC Criteria: May 8, 2018
• Last Verified: May 1, 2018

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Heart Diseases; Cardiovascular Diseases; Heart Failure
• Other Study ID Numbers: CLCZ696BKW01T