Brain Bases of Natural Scenes's Visual Perception of Natural Scenes (SCENES)

January 17, 2017 updated by: University Hospital, Grenoble

Brain Bases of Visual Perceptionnatural Scenes of Natural Scenes.

Using the available data from psychophysics, cellular electrophysiology and functionnal neuroanatomy of visual pathway, current models of visual recognition suppose that the perception of scenes start with a parallel extraction of differents elementary visual characteristics to different spatial frequencies according to a default processing principle named : 'coarse-to-fine'.

According to this principle, the visual scene's analysis would be decomposed in two steps. Fisrt, the fast analysis of the global information borne by low frequency of the scene will provide an overview of the scene's structure and would enable a first perceptive categorisation which would be then refined, approved or denied by the latest analysis of the most local, detailed and precise information, carried by the very high spatial frequency of the scene.

The research carried out since several years is preparing a biologically plausible model and to find brain bases by different imaging techniques among healthy subjects but also patients with a brain lesion and patients with a peripheral lesion.

The main goal of this Magnetic Resonance Imaging study is to find brain bases of natural scenes's visual perception of the natural scenes.

Three studies in Magnetic Resonance Imaging will be conducted, during which subjects will have to categorize pictures of natural scenes filtered in spatial frequencies. The outcome of this study will allow to refine models of visual recognition, most of them based on analysis of spatial frequencies.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

141

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • France
      • La Tronche, France, 38700
        • UniversityHospitalGrenoble

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

4 years and older (Child, Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria for young adults :

  • Subjet over 18 years and less than 30 years
  • Affiliation to a social security
  • Free signed consent
  • Medical exam done before participation to the study
  • Normal or corrected visual acuity

Exclusion Criteria four young adults :

  • Counter-argument to MRI
  • Pregnant, breast-feeding or parturient women
  • Adults non protected or unable to express their consent
  • Adults protected
  • Important earing or visual disorder
  • Neuropsychiatric disorder current or past passée ou présente (exept benign epilepsy)
  • Severe affection on a general level (cardiac, respiratory, hematologic, renal, hépatic, cancerous)
  • Drug treatment in progress (exept anti-epileptic drug) likely to de modulate brain activity

Inclusion Criteria for old adults :

  • Subjet over 50 years
  • Affiliation to a social security
  • Free signed consent
  • Medical exam done before participation to the study
  • Normal or corrected visual acuity

Exclusion Criteria four old adults :

  • Counter-argument to MRI
  • Pregnant, breast-feeding or parturient women
  • Adults non protected or unable to express their consent
  • Adults protected
  • Important earing or visual disorder
  • Neuropsychiatric disorder current or past passée ou présente (exept benign epilepsy)
  • Severe affection on a general level (cardiac, respiratory, hematologic, renal, hépatic, cancerous)
  • Drug treatment in progress (exept anti-epileptic drug) likely to de modulate brain activity

Inclusion Criteria for children :

  • Children between 4 and 12 years
  • Affiliation to a social security
  • Free signed consent
  • Medical exam done before participation to the study
  • Normal or corrected visual acuity

Exclusion Criteria four children :

  • Counter-argument to MRI
  • Important earing or visual disorder
  • Important development disorder and/or acquisitions identified by parents and/or school teachers
  • Neuropsychiatric disorder current or past passée ou présente (exept benign epilepsy)
  • Severe affection on a general level (cardiac, respiratory, hematologic, renal, hépatic, cancerous)
  • Drug treatment in progress (exept anti-epileptic drug) likely to de modulate brain activity

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Other: Expérience 1
Brain bases of spatial frequencies treatment 30 young adults, 20 old adults 20 children between 4 and 6 years, 20 children between 6 and 12 years and 20 young adults
Other: Evaluation of visual function
Other: Magnetic Resonance Imaging
Other Names:
  • MRI
Other: Expérience 2
Brain bases of Computer to Film (CtF) analysis 30 young adults, 20 old adults
Other: Evaluation of visual function
Other: Magnetic Resonance Imaging
Other Names:
  • MRI
Other: Expérience 3
Part of parahippocampal gyrus in Computer to Film (CtF) analysis 30 young adults, 20 old adults.
Other: Evaluation of visual function
Other: Magnetic Resonance Imaging
Other Names:
  • MRI

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Identify brain bases of natural scenes's visual perception of the natural scenes
Time Frame: About 80 minutes

Evaluation 1 = Visual tasks Experience 1 : Brain bases of spatial frequencies treatment Experience 2 : Brain bases of Computer to Film (CtF) natural scenes analysis MRI exam Experience 3 : Part of parahippocampal gyrus in Computer to Film (CtF) natural scenes analysis MRI exam About 30 minutes

Evaluation 2 = Retinotopy : only adults that have shown activations inside occipital cortex during evaluation 1 MRI exam about 50 minutes
About 80 minutes

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University Hospital, Grenoble

Investigators

  • Principal Investigator: Alexandre Krainik, Professor, Grenoble Hospital University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

April 1, 2012

Primary Completion (Actual)

March 1, 2016

Study Completion (Actual)

August 1, 2016

Study Registration Dates

First Submitted

July 18, 2016

First Submitted That Met QC Criteria

July 18, 2016

First Posted (Estimate)

July 21, 2016

Study Record Updates

Last Update Posted (Estimate)

January 18, 2017

Last Update Submitted That Met QC Criteria

January 17, 2017

Last Verified

January 1, 2017

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 38RC11.221

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Healthy Volunteer

Clinical Trials on Evaluation of visual function

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bahrain

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe